Angiogenesis, Metastasis, and the Cellular Microenvironment:

A Role for Fibroblasts in Mediating the Effects of Tobacco-Induced Epithelial Cell Growth and Invasion

Jean-Philippe Coppe, Megan Boysen, Chung Ho Sun, Brian J.F. Wong, Mo K. Kang, No-Hee Park, Pierre-Yves Desprez, Judith Campisi, and Ana Krtolica
Mol Cancer Res 2008 6: 1085-1098 doi: 10.1158/1541-7786.MCR-08-0062 [Abstract] [Full Text] [PDF]  

Signal Transducer and Activator of Transcription 3 Is Required for Hypoxia-Inducible Factor-1 RNA Expression in Both Tumor Cells and Tumor-Associated Myeloid Cells

Guilian Niu, Jon Briggs, Jiehui Deng, Yihong Ma, Heehyoung Lee, Marcin Kortylewski, Maciej Kujawski, Heidi Kay, W. Douglas Cress, Richard Jove, and Hua Yu
Mol Cancer Res 2008 6: 1099-1105 doi: 10.1158/1541-7786.MCR-07-2177 [Abstract] [Full Text] [PDF]  

Tumor-Derived Extracellular Mutations of PTPRT/PTP Are Defective in Cell Adhesion

Jianshi Yu, Scott Becka, Peng Zhang, Xiaodong Zhang, Susann M. Brady-Kalnay, and Zhenghe Wang
Mol Cancer Res 2008 6: 1106-1113 doi: 10.1158/1541-7786.MCR-07-2123 [Abstract] [Full Text] [PDF]  

Cancer Genes and Genomics:

Frequency and Timing of Loss of Imprinting at 11p13 and 11p15 in Wilms' Tumor Development

Keith W. Brown, Frances Power, Beth Moore, Adrian K. Charles, and Karim T.A. Malik
Mol Cancer Res 2008 6: 1114-1123 doi: 10.1158/1541-7786.MCR-08-0002 [Abstract] [Full Text] [PDF] Supplementary Data  

Oncogenic Ras and Transforming Growth Factor-β Synergistically Regulate AU-Rich Element–Containing mRNAs during Epithelial to Mesenchymal Transition

Cindy L. Kanies, J. Joshua Smith, Christian Kis, Carl Schmidt, Shawn Levy, Khalid S.A. Khabar, Jason Morrow, Natasha Deane, Dan A. Dixon, and R. Daniel Beauchamp
Mol Cancer Res 2008 6: 1124-1136 doi: 10.1158/1541-7786.MCR-07-2095 [Abstract] [Full Text] [PDF] Supplementary Data  

Gain-of-Function Mutations in the Extracellular Domain of KIT Are Common in Canine Mast Cell Tumors

Sébastien Letard, Ying Yang, Katia Hanssens, Fabienne Palmérini, Phillip S. Leventhal, Stéphanie Guéry, Alain Moussy, Jean-Pierre Kinet, Olivier Hermine, and Patrice Dubreuil
Mol Cancer Res 2008 6: 1137-1145 doi: 10.1158/1541-7786.MCR-08-0067 [Abstract] [Full Text] [PDF] Supplementary Data  

Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations

Stephanie Ma, Kwok Wah Chan, Terence Kin-Wah Lee, Kwan Ho Tang, Jana Yim-Hung Wo, Bo-Jian Zheng, and Xin-Yuan Guan
Mol Cancer Res 2008 6: 1146-1153 doi: 10.1158/1541-7786.MCR-08-0035 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell Cycle, Cell Death, and Senescence:

Genes Involved in Differentiation, Stem Cell Renewal, and Tumorigenesis Are Modulated in Telomerase-Immortalized Human Urothelial Cells

Emma J. Chapman, Gavin Kelly, and Margaret A. Knowles
Mol Cancer Res 2008 6: 1154-1168 doi: 10.1158/1541-7786.MCR-07-2168 [Abstract] [Full Text] [PDF] Supplementary Data  

Transforming Growth Factor-β–Mediated Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Expression and Apoptosis in Hepatoma Cells Requires Functional Cooperation between Smad Proteins and Activator Protein-1

Kerstin Herzer, Anne Grosse-Wilde, Peter H. Krammer, Peter R. Galle, and Stephan Kanzler
Mol Cancer Res 2008 6: 1169-1177 doi: 10.1158/1541-7786.MCR-08-0073 [Abstract] [Full Text] [PDF]  

Increased Rac1b Expression Sustains Colorectal Tumor Cell Survival

Paulo Matos and Peter Jordan
Mol Cancer Res 2008 6: 1178-1184 doi: 10.1158/1541-7786.MCR-08-0008 [Abstract] [Full Text] [PDF]  

DNA Damage and Cellular Stress Responses:

Tumor Suppression by p53 in the Absence of Atm

S. Lawrence Bailey, Kay E. Gurley, Kyung Hoon-Kim, Karen S. Kelly-Spratt, and Christopher J. Kemp
Mol Cancer Res 2008 6: 1185-1192Published Online First June 26, 2008. doi: 10.1158/1541-7786.MCR-07-2009 [Abstract] [Full Text] [PDF]  

The Nuclear Factor-B and p53 Pathways Function Independently in Primary Cells and Transformed Fibroblasts Responding to Genotoxic Damage

Dobrila Nesic, Raelene Grumont, and Steve Gerondakis
Mol Cancer Res 2008 6: 1193-1203Published Online First June 26, 2008. doi: 10.1158/1541-7786.MCR-07-2125 [Abstract] [Full Text] [PDF]  

Signaling and Regulation:

Modulation of the Cyclin-Dependent Kinase Inhibitor p21^WAF1/Cip1 Gene by Zac1 through the Antagonistic Regulators p53 and Histone Deacetylase 1 in HeLa Cells

Pei-Yao Liu, James Yi-Hsin Chan, Hsiu-Chen Lin, Sung-Ling Wang, Shu-Ting Liu, Ching-Liang Ho, Li-Chien Chang, and Shih-Ming Huang
Mol Cancer Res 2008 6: 1204-1214 doi: 10.1158/1541-7786.MCR-08-0123 [Abstract] [Full Text] [PDF]  

The Pak4 Protein Kinase Plays a Key Role in Cell Survival and Tumorigenesis in Athymic Mice

Yingying Liu, Hang Xiao, Yanmei Tian, Tanya Nekrasova, Xingpei Hao, Hong Jin Lee, Nanjoo Suh, Chung S. Yang, and Audrey Minden
Mol Cancer Res 2008 6: 1215-1224 doi: 10.1158/1541-7786.MCR-08-0087 [Abstract] [Full Text] [PDF] Supplementary Data  

WT1 Induction of Mitogen-Activated Protein Kinase Phosphatase 3 Represents a Novel Mechanism of Growth Suppression

Debra J. Morrison, Marianne K.H. Kim, Windy Berkofsky-Fessler, and Jonathan D. Licht
Mol Cancer Res 2008 6: 1225-1231 doi: 10.1158/1541-7786.MCR-08-0078 [Abstract] [Full Text] [PDF]  

Role of Activating Transcription Factor 3 on TAp73 Stability and Apoptosis in Paclitaxel-Treated Cervical Cancer Cells

Yeo Kyoung Oh, Hyun Jung Lee, Mi-Hee Jeong, Marie Rhee, Ji-Won Mo, Eun Hyeon Song, Joong-Yeon Lim, Kyung-Hee Choi, Inho Jo, Sang Ick Park, Bin Gao, Yongil Kwon, and Won-Ho Kim
Mol Cancer Res 2008 6: 1232-1249 doi: 10.1158/1541-7786.MCR-07-0297 [Abstract] [Full Text] [PDF]  

Destabilization of ERBB2 Transcripts by Targeting 3' Untranslated Region Messenger RNA Associated HuR and Histone Deacetylase-6

Gary K. Scott, Corina Marx, Crystal E. Berger, Laura R. Saunders, Eric Verdin, Stefan Schäfer, Manfred Jung, and Christopher C. Benz
Mol Cancer Res 2008 6: 1250-1258 doi: 10.1158/1541-7786.MCR-07-2110 [Abstract] [Full Text] [PDF]  

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