2007 G.H.A. Clowes Memorial Lecture:

DNA Damage Responses: Mechanisms and Roles in Human Disease: 2007 G.H.A. Clowes Memorial Award Lecture

Michael B. Kastan
Mol Cancer Res 2008 6: 517-524 doi: 10.1158/1541-7786.MCR-08-0020 [Abstract] [Full Text] [PDF]  

Angiogenesis, Metastasis, and the Cellular Microenvironment:

Vascular Endothelial Growth Factor Stimulates Organ-Specific Host Matrix Metalloproteinase-9 Expression and Ovarian Cancer Invasion

Dorina Belotti, Catia Calcagno, Angela Garofalo, Daniela Caronia, Elena Riccardi, Raffaella Giavazzi, and Giulia Taraboletti
Mol Cancer Res 2008 6: 525-534 doi: 10.1158/1541-7786.MCR-07-0366 [Abstract] [Full Text] [PDF]  

Arachidonic Acid–Induced Ca²⁺ Entry Is Involved in Early Steps of Tumor Angiogenesis

Alessandra Fiorio Pla, Cristina Grange, Susanna Antoniotti, Cristiana Tomatis, Annalisa Merlino, Benedetta Bussolati, and Luca Munaron
Mol Cancer Res 2008 6: 535-545 doi: 10.1158/1541-7786.MCR-07-0271 [Abstract] [Full Text] [PDF]  

CXCL16 Functions as a Novel Chemotactic Factor for Prostate Cancer Cells In vitro

Yi Lu, Jianhua Wang, Yang Xu, Alisa E. Koch, Zhong Cai, Xue Chen, Deborah L. Galson, Russell S. Taichman, and Jian Zhang
Mol Cancer Res 2008 6: 546-554Published Online First March 14, 2008. doi: 10.1158/1541-7786.MCR-07-0277 [Abstract] [Full Text] [PDF]  

MUC1 Initiates Src-CrkL-Rac1/Cdc42–Mediated Actin Cytoskeletal Protrusive Motility after Ligating Intercellular Adhesion Molecule-1

Qiang Shen, Jennifer J. Rahn, Jing Zhang, Nirosha Gunasekera, Xuejun Sun, Andrew R.E. Shaw, Michael J. Hendzel, Pat Hoffman, Ashlyn Bernier, and Judith C. Hugh
Mol Cancer Res 2008 6: 555-567 doi: 10.1158/1541-7786.MCR-07-2033 [Abstract] [Full Text] [PDF]  

Gene-Viral Cancer Therapy Using Dual-Regulated Oncolytic Adenovirus with Antiangiogenesis Gene for Increased Efficacy

Changqing Su, Manli Na, Jie Chen, Xinghua Wang, Yongjing Liu, Weiguo Wang, Qi Zhang, Linfang Li, Ju Long, Xinyuan Liu, Mengchao Wu, Xiaolong Fan, and Qijun Qian
Mol Cancer Res 2008 6: 568-575Published Online First March 14, 2008. doi: 10.1158/1541-7786.MCR-07-0073 [Abstract] [Full Text] [PDF]  

Cancer Genes and Genomics:

A Different View on DNA Amplifications Indicates Frequent, Highly Complex, and Stable Amplicons on 12q13-21 in Glioma

Ulrike Fischer, Andreas Keller, Petra Leidinger, Stephanie Deutscher, Sabrina Heisel, Steffi Urbschat, Hans-Peter Lenhof, and Eckart Meese
Mol Cancer Res 2008 6: 576-584 doi: 10.1158/1541-7786.MCR-07-0283 [Abstract] [Full Text] [PDF]  

The CpG Island Methylator Phenotype Correlates with Long-Range Epigenetic Silencing in Colorectal Cancer

Pawel Karpinski, David Ramsey, Zygmunt Grzebieniak, Maria M. Sasiadek, and Nikolaus Blin
Mol Cancer Res 2008 6: 585-591 doi: 10.1158/1541-7786.MCR-07-2158 [Abstract] [Full Text] [PDF]  

Monochromosome Transfer and Microarray Analysis Identify a Critical Tumor-Suppressive Region Mapping to Chromosome 13q14 and THSD1 in Esophageal Carcinoma

Josephine M.Y. Ko, Pui Ling Chan, Wing Lung Yau, Ho Kin Chan, King Chi Chan, Zhuo You Yu, Fung Mei Kwong, Lance D. Miller, Edison T. Liu, Li Chun Yang, Paulisally H.Y. Lo, Eric J. Stanbridge, Johnny C.O. Tang, Gopesh Srivastava, Sai Wah Tsao, Simon Law, and Maria L. Lung
Mol Cancer Res 2008 6: 592-603 doi: 10.1158/1541-7786.MCR-07-0154 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell Cycle, Cell Death, and Senescence:

Localization of Fas/CD95 into the Lipid Rafts on Down-Modulation of the Phosphatidylinositol 3-Kinase Signaling Pathway

Marie Bénéteau, Mathieu Pizon, Benjamin Chaigne-Delalande, Sophie Daburon, Patrick Moreau, Francesca De Giorgi, François Ichas, Amélie Rebillard, Marie-Thérèse Dimanche-Boitrel, Jean-Luc Taupin, Jean-François Moreau, and Patrick Legembre
Mol Cancer Res 2008 6: 604-613 doi: 10.1158/1541-7786.MCR-07-0331 [Abstract] [Full Text] [PDF] Supplementary Data  

Down-Regulation of Class II Phosphoinositide 3-Kinase Expression below a Critical Threshold Induces Apoptotic Cell Death

Winfried Elis, Ellen Triantafellow, Natalie M. Wolters, Katie R. Sian, Giordano Caponigro, Jason Borawski, L. Alex Gaither, Leon O. Murphy, Peter M. Finan, and Jeffrey P. MacKeigan
Mol Cancer Res 2008 6: 614-623 doi: 10.1158/1541-7786.MCR-07-0262 [Abstract] [Full Text] [PDF]  

DNA Damage and Cellular Stress Responses:

DUSP1 Is Controlled by p53 during the Cellular Response to Oxidative Stress

Yu-Xin Liu, Jianli Wang, Jianfen Guo, Jingjing Wu, Howard B. Lieberman, and Yuxin Yin
Mol Cancer Res 2008 6: 624-633 doi: 10.1158/1541-7786.MCR-07-2019 [Abstract] [Full Text] [PDF]  

Signaling and Regulation:

Prolactin Does Not Require Insulin-Like Growth Factor Intermediates but Synergizes with Insulin-Like Growth Factor I in Human Breast Cancer Cells

Kristopher C. Carver and Linda A. Schuler
Mol Cancer Res 2008 6: 634-643 doi: 10.1158/1541-7786.MCR-07-2069 [Abstract] [Full Text] [PDF]  

Proteolytic Processing of Cut Homeobox 1 by Neutrophil Elastase in the MV4;11 Myeloid Leukemia Cell Line

Brigitte Goulet, Yelena Markovic, Lam Leduy, and Alain Nepveu
Mol Cancer Res 2008 6: 644-653 doi: 10.1158/1541-7786.MCR-07-0268 [Abstract] [Full Text] [PDF]  

Hyperphosphorylated Cortactin in Cancer Cells Plays an Inhibitory Role in Cell Motility

Lin Jia, Takamasa Uekita, and Ryuichi Sakai
Mol Cancer Res 2008 6: 654-662 doi: 10.1158/1541-7786.MCR-07-0220 [Abstract] [Full Text] [PDF]  

Antiproliferative Effects by Let-7 Repression of High-Mobility Group A2 in Uterine Leiomyoma

Yi Peng, Jordan Laser, Guizhi Shi, Khush Mittal, Jonathan Melamed, Peng Lee, and Jian-Jun Wei
Mol Cancer Res 2008 6: 663-673 doi: 10.1158/1541-7786.MCR-07-0370 [Abstract] [Full Text] [PDF]  

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