Angiogenesis, Metastasis, and the Cellular Microenvironment:

17-Allylamino-17-Demethoxygeldanamycin Down-Regulates Hyaluronic Acid–Induced Glioma Invasion by Blocking Matrix Metalloproteinase-9 Secretion

Mi-Suk Kim, Hee-Jin Kwak, Ji-Woo Lee, Hea-Jin Kim, Myung-Jin Park, Jong-Bae Park, Kyung-Ho Choi, Heon Yoo, Sang-Hoon Shin, Woon-Seob Shin, Eun-Sook Song, and Seung-Hoon Lee
Mol Cancer Res 2008 6: 1657-1665Published Online First October 30, 2008. doi: 10.1158/1541-7786.MCR-08-0034 [Abstract] [Full Text] [PDF]  

Enforced Expression of MCAM/MUC18 Increases In vitro Motility and Invasiveness and In vivo Metastasis of Two Mouse Melanoma K1735 Sublines in a Syngeneic Mouse Model

Guang-Jer Wu, Pingping Fu, Shur-Wen Wang, and Mei-Whey H. Wu
Mol Cancer Res 2008 6: 1666-1677 doi: 10.1158/1541-7786.MCR-07-2200 [Abstract] [Full Text] [PDF]  

Cancer Genes and Genomics:

Mutation of ERBB2 Provides a Novel Alternative Mechanism for the Ubiquitous Activation of RAS-MAPK in Ovarian Serous Low Malignant Potential Tumors

Michael S. Anglesio, Jeremy M. Arnold, Joshy George, Anna V. Tinker, Richard Tothill, Nic Waddell, Lisa Simms, Bianca Locandro, Sian Fereday, Nadia Traficante, Peter Russell, Raghwa Sharma, Michael J. Birrer, AOCS Study Group, Anna deFazio, Georgia Chenevix-Trench, and David D.L. Bowtell
Mol Cancer Res 2008 6: 1678-1690 doi: 10.1158/1541-7786.MCR-08-0193 [Abstract] [Full Text] [PDF] Supplementary Data  

Profiling Human Androgen Receptor Mutations Reveals Treatment Effects in a Mouse Model of Prostate Cancer

Orla A. O'Mahony, Mara P. Steinkamp, Megan A. Albertelli, Michele Brogley, Haniya Rehman, and Diane M. Robins
Mol Cancer Res 2008 6: 1691-1701 doi: 10.1158/1541-7786.MCR-08-0273 [Abstract] [Full Text] [PDF] Supplementary Data  

High-Throughput Hacking of the Methylation Patterns in Breast Cancer by In vitro Transcription and Thymidine-Specific Cleavage Mass Array on MALDI-TOF Silico-Chip

Ramin Radpour, Mahdi Montazer Haghighi, Alex Xiu-Cheng Fan, Peyman Mohammadi Torbati, Sinuhe Hahn, Wolfgang Holzgreve, and Xiao Yan Zhong
Mol Cancer Res 2008 6: 1702-1709 doi: 10.1158/1541-7786.MCR-08-0262 [Abstract] [Full Text] [PDF] Supplementary Data  

Overexpression and Hypomethylation of Flap Endonuclease 1 Gene in Breast and Other Cancers

Purnima Singh, Ming Yang, Huifang Dai, Dianke Yu, Qin Huang, Wen Tan, Kemp H. Kernstine, Dongxin Lin, and Binghui Shen
Mol Cancer Res 2008 6: 1710-1717 doi: 10.1158/1541-7786.MCR-08-0269 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell Cycle, Cell Death, and Senescence:

Opposing Roles of c-Jun NH₂-Terminal Kinase and p38 Mitogen-Activated Protein Kinase in the Cellular Response to Ionizing Radiation in Human Cervical Cancer Cells

Min-Jung Kim, Soon-Young Choi, In-Chul Park, Sang-Gu Hwang, Changil Kim, Young-Hyun Choi, Haekwon Kim, Kee-Ho Lee, and Su-Jae Lee
Mol Cancer Res 2008 6: 1718-1731 doi: 10.1158/1541-7786.MCR-08-0032 [Abstract] [Full Text] [PDF] Supplementary Data  

Expression of an IFN-Inducible Cellular Senescence Gene, IFI16, Is Up-Regulated by p53

Lynda Li Song, Fatouma Alimirah, Ravichandran Panchanathan, Hong Xin, and Divaker Choubey
Mol Cancer Res 2008 6: 1732-1741Published Online First October 30, 2008. doi: 10.1158/1541-7786.MCR-08-0208 [Abstract] [Full Text] [PDF]  

Antisense MDM2 Enhances E2F1-Induced Apoptosis and the Combination Sensitizes Androgen-Dependent and Androgen-Independent Prostate Cancer Cells to Radiation

Thirupandiyur S. Udayakumar, Paul Hachem, Mansoor M. Ahmed, Sudhir Agrawal, and Alan Pollack
Mol Cancer Res 2008 6: 1742-1754 doi: 10.1158/1541-7786.MCR-08-0102 [Abstract] [Full Text] [PDF]  

Signaling and Regulation:

Mesothelin-Induced Pancreatic Cancer Cell Proliferation Involves Alteration of Cyclin E via Activation of Signal Transducer and Activator of Transcription Protein 3

Uddalak Bharadwaj, Min Li, Changyi Chen, and Qizhi Yao
Mol Cancer Res 2008 6: 1755-1765 doi: 10.1158/1541-7786.MCR-08-0095 [Abstract] [Full Text] [PDF]  

Inhibition of Src Family Kinases with Dasatinib Blocks Migration and Invasion of Human Melanoma Cells

Ralf Buettner, Tania Mesa, Adina Vultur, Frank Lee, and Richard Jove
Mol Cancer Res 2008 6: 1766-1774 doi: 10.1158/1541-7786.MCR-08-0169 [Abstract] [Full Text] [PDF]  

Luteinizing Hormone–Induced Up-Regulation of ErbB-2 Is Insufficient Stimulant of Growth and Invasion in Ovarian Cancer Cells

Susanne W. Warrenfeltz, Stephen A. Lott, Travis M. Palmer, Judy C. Gray, and David Puett
Mol Cancer Res 2008 6: 1775-1785 doi: 10.1158/1541-7786.MCR-08-0214 [Abstract] [Full Text] [PDF] Supplementary Data  

Period 2 Mutation Accelerates Apc^Min/+ Tumorigenesis

Patricia A. Wood, Xiaoming Yang, Andrew Taber, Eun-Young Oh, Christine Ansell, Stacy E. Ayers, Ziad Al-Assaad, Kevin Carnevale, Franklin G. Berger, Maria Marjorette O. Peña, and William J.M. Hrushesky
Mol Cancer Res 2008 6: 1786-1793 doi: 10.1158/1541-7786.MCR-08-0196 [Abstract] [Full Text] [PDF] Supplementary Data  

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