Subject Review:

Pharmacogenetics and Regulation of Human Cytochrome P450 1B1: Implications in Hormone-Mediated Tumor Metabolism and a Novel Target for Therapeutic Intervention

Tristan M. Sissung, Douglas K. Price, Alex Sparreboom, and William D. Figg
Mol Cancer Res 2006 4: 135-150 doi: 10.1158/1541-7786.MCR-05-0101 [Abstract] [Full Text] [PDF]  

Angiogenesis, Metastasis, and the Cellular Microenvironment:

SSeCKS/Gravin/AKAP12 Metastasis Suppressor Inhibits Podosome Formation via RhoA- and Cdc42-Dependent Pathways

Irwin H. Gelman and Lingqiu Gao
Mol Cancer Res 2006 4: 151-158 doi: 10.1158/1541-7786.MCR-05-0252 [Abstract] [Full Text] [PDF]  

Activation of Peroxisome Proliferator-Activated Receptor- Decreases Pancreatic Cancer Cell Invasion through Modulation of the Plasminogen Activator System

Hirozumi Sawai, Joey Liu, Howard A. Reber, Oscar J. Hines, and Guido Eibl
Mol Cancer Res 2006 4: 159-167 doi: 10.1158/1541-7786.MCR-05-0257 [Abstract] [Full Text] [PDF]  

Cancer Genes and Genomics:

Genomic and Expression Analysis of the 3q25-q26 Amplification Unit Reveals TLOC1/SEC62 as a Probable Target Gene in Prostate Cancer

Volker Jung, Roland Kindich, Jörn Kamradt, Martin Jung, Mirko Müller, Wolfgang A. Schulz, Rainer Engers, Gerhard Unteregger, Michael Stöckle, Richard Zimmermann, and Bernd Wullich
Mol Cancer Res 2006 4: 169-176Published Online First March 3, 2006. doi: 10.1158/1541-7786.MCR-05-0165 [Abstract] [Full Text] [PDF]  

Cell Cycle, Cell Death, and Senescence:

VRK1 Signaling Pathway in the Context of the Proliferation Phenotype in Head and Neck Squamous Cell Carcinoma

Claudio R. Santos, María Rodríguez-Pinilla, Francisco M. Vega, José L. Rodríguez-Peralto, Sandra Blanco, Ana Sevilla, Alberto Valbuena, Teresa Hernández, André J. van Wijnen, Fengzhi Li, Enrique de Alava, Montserrat Sánchez-Céspedes, and Pedro A. Lazo
Mol Cancer Res 2006 4: 177-185Published Online First March 3, 2006. doi: 10.1158/1541-7786.MCR-05-0212 [Abstract] [Full Text] [PDF]  

DNA Damage and Cellular Stress Responses:

DNase II and the Chk2 DNA Damage Pathway Form a Genetic Barrier Blocking Replication of Horizontally Transferred DNA

Anna Bergsmedh, Jacob Ehnfors, Kohki Kawane, Noboru Motoyama, Shigekazu Nagata, and Lars Holmgren
Mol Cancer Res 2006 4: 187-195Published Online First March 3, 2006. doi: 10.1158/1541-7786.MCR-05-0262 [Abstract] [Full Text] [PDF]  

ATM Requirement in Gene Expression Responses to Ionizing Radiation in Human Lymphoblasts and Fibroblasts

Cynthia L. Innes, Alexandra N. Heinloth, Kristina G. Flores, Stella O. Sieber, Paula B. Deming, Pierre R. Bushel, William K. Kaufmann, and Richard S. Paules
Mol Cancer Res 2006 4: 197-207 doi: 10.1158/1541-7786.MCR-05-0154 [Abstract] [Full Text] [PDF]  

Signalling and Regulation:

Transforming Growth Factor-ß1 Induces Tissue Inhibitor of Metalloproteinase-1 Expression via Activation of Extracellular Signal-Regulated Kinase and Sp1 in Human Fibrosarcoma Cells

Hee-Jin Kwak, Myung-Jin Park, Hyeyoung Cho, Chang-Min Park, Sang-Ik Moon, Hyung-Chan Lee, In-Chul Park, Mi-Suk Kim, Chang Hun Rhee, and Seok-Il Hong
Mol Cancer Res 2006 4: 209-220 doi: 10.1158/1541-7786.MCR-05-0140 [Abstract] [Full Text] [PDF] Supplementary Data  

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