Molecular Pathways:

Neuregulins and Cancer

Juan Carlos Montero, Ruth Rodríguez-Barrueco, Alberto Ocaña, Elena Díaz-Rodríguez, Azucena Esparís-Ogando, and Atanasio Pandiella
Clin Cancer Res 2008 14: 3237-3241 doi: 10.1158/1078-0432.CCR-07-5133 [Abstract] [Full Text] [PDF]  

Report from the FDA:

Continuing Reassessment of the Risks of Erythropoiesis-Stimulating Agents in Patients with Cancer

Vinni Juneja, Patricia Keegan, Joseph E. Gootenberg, Mark D. Rothmann, Yuan Li Shen, Kyung Y. Lee, Karen D. Weiss, and Richard Pazdur
Clin Cancer Res 2008 14: 3242-3247 doi: 10.1158/1078-0432.CCR-07-1872 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Impact of a Single Nucleotide Polymorphism in the MDM2 Gene on Neuroblastoma Development and Aggressiveness: Results of a Pilot Study on 239 Patients

Sara Cattelani, Raffaella Defferrari, Sonia Marsilio, Rita Bussolari, Olivia Candini, Francesca Corradini, Giovanna Ferrari-Amorotti, Clara Guerzoni, Luisa Pecorari, Chiara Menin, Roberta Bertorelle, Pierluigi Altavista, Heather P. McDowell, Renata Boldrini, Carlo Dominici, Gian Paolo Tonini, Giuseppe Raschellà, and Bruno Calabretta
Clin Cancer Res 2008 14: 3248-3253 doi: 10.1158/1078-0432.CCR-07-4725 [Abstract] [Full Text] [PDF]  

Phenotypic Analysis of Prostate-Infiltrating Lymphocytes Reveals T_H17 and T_reg Skewing

Karen Sandell Sfanos, Tullia C. Bruno, Charles H. Maris, Lauren Xu, Christopher J. Thoburn, Angelo M. DeMarzo, Alan K. Meeker, William B. Isaacs, and Charles G. Drake
Clin Cancer Res 2008 14: 3254-3261 doi: 10.1158/1078-0432.CCR-07-5164 [Abstract] [Full Text] [PDF]  

Involvement of Hepcidin in the Anemia of Multiple Myeloma

Sanjai Sharma, Elizabeta Nemeth, Yi-Hsiang Chen, Julia Goodnough, Alissa Huston, G.D. Roodman, Tomas Ganz, and Alan Lichtenstein
Clin Cancer Res 2008 14: 3262-3267 doi: 10.1158/1078-0432.CCR-07-4153 [Abstract] [Full Text] [PDF]  

Activity of the Bcl-2 Family Inhibitor ABT-263 in a Panel of Small Cell Lung Cancer Xenograft Models

Alex R. Shoemaker, Michael J. Mitten, Jessica Adickes, Scott Ackler, Marion Refici, Debra Ferguson, Anatol Oleksijew, Jacqueline M. O'Connor, Baole Wang, David J. Frost, Joy Bauch, Kennan Marsh, Steven K. Tahir, Xiufen Yang, Christin Tse, Stephen W. Fesik, Saul H. Rosenberg, and Steven W. Elmore
Clin Cancer Res 2008 14: 3268-3277 doi: 10.1158/1078-0432.CCR-07-4622 [Abstract] [Full Text] [PDF]  

Mutant Epidermal Growth Factor Receptor in Benign, Borderline, and Malignant Ovarian Tumors

Karina Dahl Steffensen, Marianne Waldstrøm, Dorte Aalund Olsen, Thomas Corydon, Karen Axelgaard Lorentzen, Hans Jørgen Knudsen, Ulla Jeppesen, Ivan Brandslund, and Anders Jakobsen
Clin Cancer Res 2008 14: 3278-3282 doi: 10.1158/1078-0432.CCR-07-4171 [Abstract] [Full Text] [PDF]  

Intertumor and Intratumor NY-ESO-1 Expression Heterogeneity Is Associated with Promoter-Specific and Global DNA Methylation Status in Ovarian Cancer

Anna Woloszynska-Read, Paulette Mhawech-Fauceglia, Jihnhee Yu, Kunle Odunsi, and Adam R. Karpf
Clin Cancer Res 2008 14: 3283-3290 doi: 10.1158/1078-0432.CCR-07-5279 [Abstract] [Full Text] [PDF]  

ECSA/DPPA2 is an Embryo-Cancer Antigen that Is Coexpressed with Cancer-Testis Antigens in Non–Small Cell Lung Cancer

Thomas John, Otavia L. Caballero, Suzanne J. Svobodová, Alan Kong, Ramon Chua, Judy Browning, Sheila Fortunato, Siddhartha Deb, Melinda Hsu, Craig A. Gedye, Ian D. Davis, Nasser Altorki, Andrew J. Simpson, Yao-Tseng Chen, Marilyn Monk, and Jonathan S. Cebon
Clin Cancer Res 2008 14: 3291-3298 doi: 10.1158/1078-0432.CCR-07-1322 [Abstract] [Full Text] [PDF]  

Focal Adhesion Kinase Expression in Human Neuroblastoma: Immunohistochemical and Real-time PCR Analyses

Elizabeth A. Beierle, Nicole A. Massoll, Joseph Hartwich, Elena V. Kurenova, Vita M. Golubovskaya, William G. Cance, Patrick McGrady, and Wendy B. London
Clin Cancer Res 2008 14: 3299-3305 doi: 10.1158/1078-0432.CCR-07-1511 [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Disseminated Tumor Cells of Breast Cancer Patients: A Strong Prognostic Factor for Distant and Local Relapse

Francois-Clément Bidard, Anne Vincent-Salomon, Stéphanie Gomme, Claude Nos, Yann de Rycke, Jean Paul Thiery, Brigitte Sigal-Zafrani, Laurent Mignot, Xavier Sastre-Garau, Jean-Yves Pierga for the Institut Curie Breast Cancer Study Group
Clin Cancer Res 2008 14: 3306-3311 doi: 10.1158/1078-0432.CCR-07-4749 [Abstract] [Full Text] [PDF]  

Effect of SLCO1B3 Haplotype on Testosterone Transport and Clinical Outcome in Caucasian Patients with Androgen-Independent Prostatic Cancer

Akinobu Hamada, Tristan Sissung, Douglas K. Price, Romano Danesi, Cindy H. Chau, Nima Sharifi, David Venzon, Kenji Maeda, Keisuke Nagao, Alex Sparreboom, Hiroaki Mitsuya, William L. Dahut, and William D. Figg
Clin Cancer Res 2008 14: 3312-3318 doi: 10.1158/1078-0432.CCR-07-4118 [Abstract] [Full Text] [PDF]  

Astrocyte Elevated Gene-1 is a Novel Prognostic Marker for Breast Cancer Progression and Overall Patient Survival

Jun Li, Nu Zhang, Li-Bing Song, Wen-Ting Liao, Li-Li Jiang, Li-Yun Gong, Jueheng Wu, Jie Yuan, Hui-Zhong Zhang, Mu-Sheng Zeng, and Mengfeng Li
Clin Cancer Res 2008 14: 3319-3326 doi: 10.1158/1078-0432.CCR-07-4054 [Abstract] [Full Text] [PDF]  

Identification of Genes Differentially Expressed in Benign versus Malignant Thyroid Tumors

Nijaguna B. Prasad, Helina Somervell, Ralph P. Tufano, Alan P.B. Dackiw, Michael R. Marohn, Joseph A. Califano, Yongchun Wang, William H. Westra, Douglas P. Clark, Christopher B. Umbricht, Steven K. Libutti, and Martha A. Zeiger
Clin Cancer Res 2008 14: 3327-3337 doi: 10.1158/1078-0432.CCR-07-4495 [Abstract] [Full Text] [PDF] Supplementary Data  

AP1-Dependent Galectin-1 Expression Delineates Classical Hodgkin and Anaplastic Large Cell Lymphomas from Other Lymphoid Malignancies with Shared Molecular Features

Scott J. Rodig, Jing Ouyang, Przemyslaw Juszczynski, Treeve Currie, Kenneth Law, Donna S. Neuberg, Gabriel A. Rabinovich, Margaret A. Shipp, and Jeffery L. Kutok
Clin Cancer Res 2008 14: 3338-3344 doi: 10.1158/1078-0432.CCR-07-4709 [Abstract] [Full Text] [PDF]  

Prediction of Nodal Involvement in Breast Cancer Based on Multiparametric Protein Analyses from Preoperative Core Needle Biopsies of the Primary Lesion

Georg Sauer, Nicole Schneiderhan-Marra, Cornelia Kazmaier, Kathrin Hutzel, Karin Koretz, Rainer Muche, Rolf Kreienberg, Thomas Joos, and Helmut Deissler
Clin Cancer Res 2008 14: 3345-3353 doi: 10.1158/1078-0432.CCR-07-4802 [Abstract] [Full Text] [PDF]  

Aneuploidy Predicts Outcome in Patients with Endometrial Carcinoma and Is Related to Lack of CDH13 Hypermethylation

Yutaka Suehiro, Toshiyuki Okada, Takae Okada, Keiko Anno, Naoko Okayama, Koji Ueno, Mikako Hiura, Mikiko Nakamura, Tomoko Kondo, Atsunori Oga, Shigeto Kawauchi, Kei Hirabayashi, Fumitaka Numa, Takehisa Ito, Toshiaki Saito, Kohsuke Sasaki, and Yuji Hinoda
Clin Cancer Res 2008 14: 3354-3361 doi: 10.1158/1078-0432.CCR-07-4609 [Abstract] [Full Text] [PDF]  

Preoperative Plasma Endoglin Levels Predict Biochemical Progression After Radical Prostatectomy

Robert S. Svatek, Jose A. Karam, Claus G. Roehrborn, Pierre I. Karakiewicz, Kevin M. Slawin, and Shahrokh F. Shariat
Clin Cancer Res 2008 14: 3362-3366 doi: 10.1158/1078-0432.CCR-07-4707 [Abstract] [Full Text] [PDF]  

Genetic Polymorphism in EGF Is Associated with Prostate Cancer Aggressiveness and Progression-Free Interval in Androgen Blockade–Treated Patients

Ana L. Teixeira, Ricardo Ribeiro, Diana Cardoso, Daniela Pinto, Francisco Lobo, Avelino Fraga, Francisco Pina, Fernando Calais-da-Silva, and Rui Medeiros
Clin Cancer Res 2008 14: 3367-3371 doi: 10.1158/1078-0432.CCR-07-5119 [Abstract] [Full Text] [PDF]  

HLA Class I Antigen Processing Machinery Component Expression and Intratumoral T-Cell Infiltrate as Independent Prognostic Markers in Ovarian Carcinoma

Liz Y. Han, Mavis S. Fletcher, Diana L. Urbauer, Peter Mueller, Charles N. Landen, Aparna A. Kamat, Yvonne G. Lin, William M. Merritt, Whitney A. Spannuth, Michael T. Deavers, Koen De Geest, David M. Gershenson, Susan K. Lutgendorf, Soldano Ferrone, and Anil K. Sood
Clin Cancer Res 2008 14: 3372-3379 doi: 10.1158/1078-0432.CCR-07-4433 [Abstract] [Full Text] [PDF]  

Characterization of TMPRSS2-ERG Fusion High-Grade Prostatic Intraepithelial Neoplasia and Potential Clinical Implications

Juan-Miguel Mosquera, Sven Perner, Elizabeth M. Genega, Martin Sanda, Matthias D. Hofer, Kirsten D. Mertz, Pamela L. Paris, Jeff Simko, Tarek A. Bismar, Gustavo Ayala, Rajal B. Shah, Massimo Loda, and Mark A. Rubin
Clin Cancer Res 2008 14: 3380-3385 doi: 10.1158/1078-0432.CCR-07-5194 [Abstract] [Full Text] [PDF]  

Protein Expression of Platelet-Derived Growth Factor Receptor Correlates with Malignant Histology and PTEN with Survival in Childhood Gliomas

Halldora K. Thorarinsdottir, Mariarita Santi, Robert McCarter, Elisabeth J. Rushing, Robert Cornelison, Alessandra Jales, and Tobey J. MacDonald
Clin Cancer Res 2008 14: 3386-3394 doi: 10.1158/1078-0432.CCR-07-1616 [Abstract] [Full Text] [PDF]  

TMPRSS2:ERG Fusion Identifies a Subgroup of Prostate Cancers with a Favorable Prognosis

Outi R. Saramäki, Anna E. Harjula, Paula M. Martikainen, Robert L. Vessella, Teuvo L.J. Tammela, and Tapio Visakorpi
Clin Cancer Res 2008 14: 3395-3400 doi: 10.1158/1078-0432.CCR-07-2051 [Abstract] [Full Text] [PDF]  

Human High Molecular Weight–Melanoma-Associated Antigen: Utility for Detection of Metastatic Melanoma in Sentinel Lymph Nodes

Yasufumi Goto, Soldano Ferrone, Takaaki Arigami, Minoru Kitago, Atsushi Tanemura, Eiji Sunami, Sandy L. Nguyen, Roderick R. Turner, Donald L. Morton, and Dave S.B. Hoon
Clin Cancer Res 2008 14: 3401-3407 doi: 10.1158/1078-0432.CCR-07-1842 [Abstract] [Full Text] [PDF]  

Prognostic Significance of Defective Mismatch Repair and BRAF V600E in Patients with Colon Cancer

Amy J. French, Daniel J. Sargent, Lawrence J. Burgart, Nathan R. Foster, Brian F. Kabat, Richard Goldberg, Lois Shepherd, Harold E. Windschitl, and Stephen N. Thibodeau
Clin Cancer Res 2008 14: 3408-3415 doi: 10.1158/1078-0432.CCR-07-1489 [Abstract] [Full Text] [PDF]  

Changes in Tumor Metabolism as Readout for Mammalian Target of Rapamycin Kinase Inhibition by Rapamycin in Glioblastoma

Liu Hua Wei, Helen Su, Isabel J. Hildebrandt, Michael E. Phelps, Johannes Czernin, and Wolfgang A. Weber
Clin Cancer Res 2008 14: 3416-3426 doi: 10.1158/1078-0432.CCR-07-1824 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Development of Clinical Trials in a Cooperative Group Setting: The Eastern Cooperative Oncology Group

David M. Dilts, Alan Sandler, Steven Cheng, Joshua Crites, Lori Ferranti, Amy Wu, Robert Gray, Jean MacDonald, Donna Marinucci, and Robert Comis
Clin Cancer Res 2008 14: 3427-3433 doi: 10.1158/1078-0432.CCR-07-5060 [Abstract] [Full Text] [PDF]  

A Phase I and Pharmacokinetic Study of Weekly Oxaliplatin Followed by Paclitaxel in Patients with Solid Tumors

Tanios S. Bekaii-Saab, Jing Liu, Kenneth K. Chan, Stanley P. Balcerzak, Percy S. Ivy, Michael R. Grever, and Eric H. Kraut
Clin Cancer Res 2008 14: 3434-3440 doi: 10.1158/1078-0432.CCR-07-4903 [Abstract] [Full Text] [PDF]  

Evaluation of the Pharmacodynamic Effects of MGCD0103 from Preclinical Models to Human Using a Novel HDAC Enzyme Assay

Claire Bonfils, Ann Kalita, Marja Dubay, Lillian L. Siu, Michael A. Carducci, Gregory Reid, Robert E. Martell, Jeffrey M. Besterman, and Zuomei Li
Clin Cancer Res 2008 14: 3441-3449 doi: 10.1158/1078-0432.CCR-07-4427 [Abstract] [Full Text] [PDF]  

A Phase 1 Study of Mapatumumab (Fully Human Monoclonal Antibody to TRAIL-R1) in Patients with Advanced Solid Malignancies

Sébastien J. Hotte, Hal W. Hirte, Eric X. Chen, Lillian L. Siu, Lyly H. Le, Alfred Corey, Anne Iacobucci, Martha MacLean, Larry Lo, Norma Lynn Fox, and Amit M. Oza
Clin Cancer Res 2008 14: 3450-3455 doi: 10.1158/1078-0432.CCR-07-1416 [Abstract] [Full Text] [PDF]  

A Phase I Study of 17-Allylamino-17-Demethoxygeldanamycin Combined with Paclitaxel in Patients with Advanced Solid Malignancies

Suresh S. Ramalingam, Merrill J. Egorin, Ramesh K. Ramanathan, Scot C. Remick, Rachel P. Sikorski, Theodore F. Lagattuta, Gurkamal S. Chatta, David M. Friedland, Ronald G. Stoller, Douglas M. Potter, S. Percy Ivy, and Chandra P. Belani
Clin Cancer Res 2008 14: 3456-3461 doi: 10.1158/1078-0432.CCR-07-5088 [Abstract] [Full Text] [PDF]  

A Dose-Escalation Study of Recombinant Human Interleukin-18 Using Two Different Schedules of Administration in Patients with Cancer

Michael J. Robertson, John M. Kirkwood, Theodore F. Logan, Kevin M. Koch, Steven Kathman, Lyndon C. Kirby, William N. Bell, Linda M. Thurmond, Jill Weisenbach, and Mohammed M. Dar
Clin Cancer Res 2008 14: 3462-3469 doi: 10.1158/1078-0432.CCR-07-4740 [Abstract] [Full Text] [PDF]  

Hypertension and Rarefaction during Treatment with Telatinib, a Small Molecule Angiogenesis Inhibitor

Neeltje Steeghs, Hans Gelderblom, Jos op 't Roodt, Olaf Christensen, Prabhu Rajagopalan, Marcel Hovens, Hein Putter, Ton J. Rabelink, and Eelco de Koning
Clin Cancer Res 2008 14: 3470-3476 doi: 10.1158/1078-0432.CCR-07-5050 [Abstract] [Full Text] [PDF]  

Oral Administration of Gemcitabine in Patients with Refractory Tumors: A Clinical and Pharmacologic Study

Stephan A. Veltkamp, Robert S. Jansen, Sophie Callies, Dick Pluim, Carla M. Visseren-Grul, Hilde Rosing, Susanne Kloeker-Rhoades, Valerie A.M. Andre, Jos H. Beijnen, Christopher A. Slapak, and Jan H.M. Schellens
Clin Cancer Res 2008 14: 3477-3486 doi: 10.1158/1078-0432.CCR-07-4521 [Abstract] [Full Text] [PDF]  

Adjuvant Radioimmunotherapy Trial with Iodine-131–Labeled Anti–Carcinoembryonic Antigen Monoclonal Antibody F6 F(ab')₂ after Resection of Liver Metastases from Colorectal Cancer

Marc Ychou, David Azria, Cathy Menkarios, Patrick Faurous, François Quenet, Bernard Saint-Aubert, Philippe Rouanet, Monique Pèlegrin, Caroline Bascoul-Mollevi, Dominique Guerreau, Jean-Claude Saccavini, Jean-Pierre Mach, Jean-Claude Artus, and André Pèlegrin
Clin Cancer Res 2008 14: 3487-3493 doi: 10.1158/1078-0432.CCR-07-4698 [Abstract] [Full Text] [PDF]  

Methylated NEUROD1 Promoter is a Marker for Chemosensitivity in Breast Cancer

Heidi Fiegl, Allison Jones, Cornelia Hauser-Kronberger, Georg Hutarew, Roland Reitsamer, Robin L. Jones, Mitch Dowsett, Elisabeth Mueller-Holzner, Gudrun Windbichler, Günter Daxenbichler, Georg Goebel, Christian Ensinger, Ian Jacobs, and Martin Widschwendter
Clin Cancer Res 2008 14: 3494-3502 doi: 10.1158/1078-0432.CCR-07-4557 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Proteasome β Subunit Pharmacogenomics: Gene Resequencing and Functional Genomics

Liewei Wang, Shaji Kumar, Brooke L. Fridley, Krishna R. Kalari, Irene Moon, Linda L. Pelleymounter, Michelle A.T. Hildebrandt, Anthony Batzler, Bruce W. Eckloff, Eric D. Wieben, and Philip R. Greipp
Clin Cancer Res 2008 14: 3503-3513 doi: 10.1158/1078-0432.CCR-07-5150 [Abstract] [Full Text] [PDF]  

Retinoblastoma RB94 Enhances Radiation Treatment of Head and Neck Squamous Cell Carcinoma

Koji Araki, Sidrah M. Ahmad, Guoyan Li, David A. Bray, Jr, Koichiro Saito, Daiyou Wang, Uwe Wirtz, Sunil Sreedharan, Bert W. O'Malley, Jr, and Daqing Li
Clin Cancer Res 2008 14: 3514-3519 doi: 10.1158/1078-0432.CCR-07-4538 [Abstract] [Full Text] [PDF]  

Direct and Natural Killer Cell-Mediated Antitumor Effects of Low-Dose Bortezomib in Hepatocellular Carcinoma

Sorin Armeanu, Matthias Krusch, Katrin M. Baltz, Thomas S. Weiss, Irina Smirnow, Alexander Steinle, Ulrich M. Lauer, Michael Bitzer, and Helmut R. Salih
Clin Cancer Res 2008 14: 3520-3528 doi: 10.1158/1078-0432.CCR-07-4744 [Abstract] [Full Text] [PDF]  

Modulation of Gemcitabine (2',2'-Difluoro-2'-Deoxycytidine) Pharmacokinetics, Metabolism, and Bioavailability in Mice by 3,4,5,6-Tetrahydrouridine

Jan H. Beumer, Julie L. Eiseman, Robert A. Parise, Erin Joseph, Joseph M. Covey, and Merrill J. Egorin
Clin Cancer Res 2008 14: 3529-3535 doi: 10.1158/1078-0432.CCR-07-4885 [Abstract] [Full Text] [PDF]  

Combination of Docetaxel and Recombinant Vaccine Enhances T-Cell Responses and Antitumor Activity: Effects of Docetaxel on Immune Enhancement

Charlie T. Garnett, Jeffrey Schlom, and James W. Hodge
Clin Cancer Res 2008 14: 3536-3544 doi: 10.1158/1078-0432.CCR-07-4025 [Abstract] [Full Text] [PDF]  

Lymphocyte Activation Gene-3 Fusion Protein Increases the Potency of a Granulocyte Macrophage Colony-Stimulating Factor–Secreting Tumor Cell Immunotherapy

Betty Li, Melinda VanRoey, Frederic Triebel, and Karin Jooss
Clin Cancer Res 2008 14: 3545-3554 doi: 10.1158/1078-0432.CCR-07-5200 [Abstract] [Full Text] [PDF]  

Preclinical Evaluation of the -Particle Generator Nuclide ²²⁵Ac for Somatostatin Receptor Radiotherapy of Neuroendocrine Tumors

Matthias Miederer, Gjermund Henriksen, Andrea Alke, Ilona Mossbrugger, Leticia Quintanilla-Martinez, Reingard Senekowitsch-Schmidtke, and Markus Essler
Clin Cancer Res 2008 14: 3555-3561 doi: 10.1158/1078-0432.CCR-07-4647 [Abstract] [Full Text] [PDF]  

The Iroquois Homeobox Gene 5 Is Regulated by 1,25-Dihydroxyvitamin D₃ in Human Prostate Cancer and Regulates Apoptosis and the Cell Cycle in LNCaP Prostate Cancer Cells

Anne Myrthue, Brooks L.S. Rademacher, Janet Pittsenbarger, Bozena Kutyba-Brooks, Marin Gantner, David Z. Qian, and Tomasz M. Beer
Clin Cancer Res 2008 14: 3562-3570 doi: 10.1158/1078-0432.CCR-07-4649 [Abstract] [Full Text] [PDF]  

Combining Nanoliposomal Ceramide with Sorafenib Synergistically Inhibits Melanoma and Breast Cancer Cell Survival to Decrease Tumor Development

Melissa A. Tran, Charles D. Smith, Mark Kester, and Gavin P. Robertson
Clin Cancer Res 2008 14: 3571-3581 doi: 10.1158/1078-0432.CCR-07-4881 [Abstract] [Full Text] [PDF]  

A Fiber-Modified Mesothelin Promoter–Based Conditionally Replicating Adenovirus for Treatment of Ovarian Cancer

Yuko Tsuruta, Larisa Pereboeva, Martina Breidenbach, Daniel T. Rein, Minghui Wang, Ronald D. Alvarez, Gene P. Siegal, Paul Dent, Paul B. Fisher, and David T. Curiel
Clin Cancer Res 2008 14: 3582-3588 doi: 10.1158/1078-0432.CCR-07-5053 [Abstract] [Full Text] [PDF]  

Combination Strategy Targeting the Hypoxia Inducible Factor-1 with Mammalian Target of Rapamycin and Histone Deacetylase Inhibitors

Henk M.W. Verheul, Brenda Salumbides, Karen Van Erp, Hans Hammers, David Z. Qian, Tolib Sanni, Peter Atadja, and Roberto Pili
Clin Cancer Res 2008 14: 3589-3597 doi: 10.1158/1078-0432.CCR-07-4306 [Abstract] [Full Text] [PDF]  

A Paclitaxel-Hyaluronan Bioconjugate Targeting Ovarian Cancer Affords a Potent In vivo Therapeutic Activity

Alessandra Banzato, Sara Bobisse, Maria Rondina, Davide Renier, Fabio Bettella, Giovanni Esposito, Luigi Quintieri, Laura Meléndez-Alafort, Ulderico Mazzi, Paola Zanovello, and Antonio Rosato
Clin Cancer Res 2008 14: 3598-3606 doi: 10.1158/1078-0432.CCR-07-2019 [Abstract] [Full Text] [PDF]  

Nonviral Nanoscale-Based Delivery of Antisense Oligonucleotides Targeted to Hypoxia-Inducible Factor 1 Enhances the Efficacy of Chemotherapy in Drug-Resistant Tumor

Yang Wang, Maha Saad, Refika I. Pakunlu, Jayant J. Khandare, Olga B. Garbuzenko, Alexandre A. Vetcher, Viatcheslav A. Soldatenkov, Vitaly P. Pozharov, and Tamara Minko
Clin Cancer Res 2008 14: 3607-3616 doi: 10.1158/1078-0432.CCR-07-2020 [Abstract] [Full Text] [PDF]  

Matrix metalloproteinase-9 Inhibition Down-Regulates Radiation-Induced Nuclear Factor-B Activity Leading to Apoptosis in Breast Tumors

Sateesh Kunigal, Sajani S. Lakka, Pushpa Joseph, Norman Estes, and Jasti S. Rao
Clin Cancer Res 2008 14: 3617-3626 doi: 10.1158/1078-0432.CCR-07-2060 [Abstract] [Full Text] [PDF]  

Cancer Prevention and Susceptibility:

Gly⁸²Ser Polymorphism of the Receptor for Advanced Glycation End Products Is Associated with an Increased Risk of Gastric Cancer in a Chinese Population

Haijuan Gu, Li Yang, Qingmin Sun, Bo Zhou, Naping Tang, Rihong Cong, Ying Zeng, and Bin Wang
Clin Cancer Res 2008 14: 3627-3632 doi: 10.1158/1078-0432.CCR-07-4808 [Abstract] [Full Text] [PDF]  

A Novel Functional Polymorphism C1797G in the MDM2 Promoter Is Associated with Risk of Bladder Cancer in a Chinese Population

Meilin Wang, Zhizhong Zhang, Haixia Zhu, Guangbo Fu, Shouyu Wang, Dongmei Wu, Jianwei Zhou, Qingyi Wei, and Zhengdong Zhang
Clin Cancer Res 2008 14: 3633-3640 doi: 10.1158/1078-0432.CCR-07-5155 [Abstract] [Full Text] [PDF]  

Corrections:

Corrrection: Article on Cardiac Toxicity and Trastuzumab Combined with Pertuzumab

Clin Cancer Res 2008 14: 3641 doi: 10.1158/1078-0432.CCR-14-11-COR [Full Text] [PDF]  

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