The Biology Behind:

Multiple Etiologies of Tumor Hypoxia Require Multifaceted Solutions

Mark W. Dewhirst, Isabel Cardenas Navia, David M. Brizel, Christopher Willett, and Timothy W. Secomb
Clin Cancer Res 2007 13: 375 -377 doi: 10.1158/1078-0432.CCR-06-2629 [Full Text] [PDF]  

Molecular Pathways:

PTEN-Mediated Resistance to Epidermal Growth Factor Receptor Kinase Inhibitors

Ingo K. Mellinghoff, Tim F. Cloughesy, and Paul S. Mischel
Clin Cancer Res 2007 13: 378-381 doi: 10.1158/1078-0432.CCR-06-1992 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Decreased NKG2D Expression on CD8⁺ T Cell Is Involved in Immune Evasion in Patients with Gastric Cancer

Tomohiro Osaki, Hiroaki Saito, Toshiaki Yoshikawa, Sachiko Matsumoto, Shigeru Tatebe, Shunichi Tsujitani, and Masahide Ikeguchi
Clin Cancer Res 2007 13: 382-387 doi: 10.1158/1078-0432.CCR-06-1454 [Abstract] [Full Text] [PDF]  

CD8+ T-Cell Content in Diagnostic Lymph Nodes Measured by Flow Cytometry Is a Predictor of Survival in Follicular Lymphoma

Björn Engelbrekt Wahlin, Birgitta Sander, Birger Christensson, and Eva Kimby
Clin Cancer Res 2007 13: 388-397 doi: 10.1158/1078-0432.CCR-06-1734 [Abstract] [Full Text] [PDF]  

Microarray-Based Identification of Tenascin C and Tenascin XB, Genes Possibly Involved in Tumorigenesis Associated with Neurofibromatosis Type 1

Pascale Lévy, Hugues Ripoche, Ingrid Laurendeau, Vladimir Lazar, Nicolas Ortonne, Béatrice Parfait, Karen Leroy, Janine Wechsler, Isabelle Salmon, Pierre Wolkenstein, Philippe Dessen, Michel Vidaud, Dominique Vidaud, and Ivan Bièche
Clin Cancer Res 2007 13: 398-407 Published Online First January 3, 2007. doi: 10.1158/1078-0432.CCR-06-0182 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinicopathologic Analysis of Breast Cancers with PIK3CA Mutations in Japanese Women

Naomi Maruyama, Yasuo Miyoshi, Tetsuya Taguchi, Yasuhiro Tamaki, Morito Monden, and Shinzaburo Noguchi
Clin Cancer Res 2007 13: 408-414 Published Online First January 3, 2007. doi: 10.1158/1078-0432.CCR-06-0267 [Abstract] [Full Text] [PDF]  

Gene Expression Signature and the Prediction of Ulcerative Colitis–Associated Colorectal Cancer by DNA Microarray

Toshiaki Watanabe, Takashi Kobunai, Etsuko Toda, Takamitsu Kanazawa, Yoshihiro Kazama, Junichiro Tanaka, Toshiaki Tanaka, Yoko Yamamoto, Keisuke Hata, Tetsu Kojima, Tadashi Yokoyama, Tsuyoshi Konishi, Yoshihiro Okayama, Yoshikazu Sugimoto, Toshinori Oka, Shin Sasaki, Yohichi Ajioka, Tetsuichiro Muto, and Hirokazu Nagawa
Clin Cancer Res 2007 13: 415-420 doi: 10.1158/1078-0432.CCR-06-0753 [Abstract] [Full Text] [PDF] Supplementary Data  

Imaging, Diagnosis, Prognosis:

Circulating Mitochondrial Nucleic Acids Have Prognostic Value for Survival in Patients with Advanced Prostate Cancer

Niven Mehra, Maarten Penning, Jolanda Maas, Nancy van Daal, Rachel H. Giles, and Emile E. Voest
Clin Cancer Res 2007 13: 421-426 doi: 10.1158/1078-0432.CCR-06-1087 [Abstract] [Full Text] [PDF]  

Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography Predicts Tumor Differentiation, P-glycoprotein Expression, and Outcome after Resection in Hepatocellular Carcinoma

Satoru Seo, Etsuro Hatano, Tatsuya Higashi, Tadashi Hara, Masaharu Tada, Nobuyuki Tamaki, Keiko Iwaisako, Iwao Ikai, and Shinji Uemoto
Clin Cancer Res 2007 13: 427-433 doi: 10.1158/1078-0432.CCR-06-1357 [Abstract] [Full Text] [PDF]  

Increased Expression of Insulin-like Growth Factor-II Messenger RNA–Binding Protein 1 Is Associated with Tumor Progression in Patients with Lung Cancer

Tatsuya Kato, Satoshi Hayama, Takumi Yamabuki, Nobuhisa Ishikawa, Masaki Miyamoto, Tomoo Ito, Eiju Tsuchiya, Satoshi Kondo, Yusuke Nakamura, and Yataro Daigo
Clin Cancer Res 2007 13: 434-442 doi: 10.1158/1078-0432.CCR-06-1297 [Abstract] [Full Text] [PDF]  

Prospective Early Response Imaging Biomarker for Neoadjuvant Breast Cancer Chemotherapy

Kuei C. Lee, Bradford A. Moffat, Anne F. Schott, Rachel Layman, Steven Ellingworth, Rebecca Juliar, Amjad P. Khan, Mark Helvie, Charles R. Meyer, Thomas L. Chenevert, Alnawaz Rehemtulla, and Brian D. Ross
Clin Cancer Res 2007 13: 443-450 doi: 10.1158/1078-0432.CCR-06-1888 [Abstract] [Full Text] [PDF]  

Prognostic Role of the Reduced Folate Carrier, the Major Membrane Transporter for Methotrexate, in Childhood Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group

Yubin Ge, Christina L. Haska, Katherine LaFiura, Meenakshi Devidas, Stephen B. Linda, Mingjun Liu, Ronald Thomas, Jeffrey W. Taub, and Larry H. Matherly
Clin Cancer Res 2007 13: 451-457 doi: 10.1158/1078-0432.CCR-06-2145 [Abstract] [Full Text] [PDF]  

An Integrated Clinical-Genomics Approach Identifies a Candidate Multi-Analyte Blood Test for Serous Ovarian Carcinoma

Ivo Meinhold-Heerlein, Dirk Bauerschlag, Yingyao Zhou, Lisa M. Sapinoso, Keith Ching, Henry Frierson, Jr., Karen Bräutigam, Jalid Sehouli, Elmar Stickeler, Dominique Könsgen, Felix Hilpert, Constantin S. von Kaisenberg, Jacobus Pfisterer, Thomas Bauknecht, Walter Jonat, Norbert Arnold, and Garret M. Hampton
Clin Cancer Res 2007 13: 458-466 doi: 10.1158/1078-0432.CCR-06-0691 [Abstract] [Full Text] [PDF] Supplementary Data  

BNIP3 as a Progression Marker in Primary Human Breast Cancer; Opposing Functions in In situ Versus Invasive Cancer

Ern Yu Tan, Leticia Campo, Cheng Han, Helen Turley, Francesco Pezzella, Kevin C. Gatter, Adrian L. Harris, and Stephen B. Fox
Clin Cancer Res 2007 13: 467-474 doi: 10.1158/1078-0432.CCR-06-1466 [Abstract] [Full Text] [PDF]  

Lumbar Bone Marrow Microcirculation Measurements from Dynamic Contrast-Enhanced Magnetic Resonance Imaging Is a Predictor of Event-Free Survival in Progressive Multiple Myeloma

Jens Hillengass, Klaus Wasser, Stefan Delorme, Fabian Kiessling, Christian Zechmann, Axel Benner, Hans-Ulrich Kauczor, Anthony D. Ho, Hartmut Goldschmidt, and Thomas M. Moehler
Clin Cancer Res 2007 13: 475-481 doi: 10.1158/1078-0432.CCR-06-0061 [Abstract] [Full Text] [PDF]  

Genetic Deletions in Sputum as Diagnostic Markers for Early Detection of Stage I Non–Small Cell Lung Cancer

Ruiyun Li, Nevins W. Todd, Qi Qiu, Tao Fan, Richard Y. Zhao, William H. Rodgers, Hong-Bin Fang, Ruth L. Katz, Sanford A. Stass, and Feng Jiang
Clin Cancer Res 2007 13: 482-487 doi: 10.1158/1078-0432.CCR-06-1593 [Abstract] [Full Text] [PDF]  

Protein Expression Profiling in High-Risk Breast Cancer Patients Treated with High-Dose or Conventional Dose–Dense Chemotherapy

Raihanatou Diallo-Danebrock, Evelyn Ting, Oleg Gluz, Alexander Herr, Svjetlana Mohrmann, Helene Geddert, Achim Rody, Karl-Ludwig Schaefer, Stephan E. Baldus, Arndt Hartmann, Peter J. Wild, Michael Burson, Helmut E. Gabbert, Ulrike Nitz, and Christopher Poremba
Clin Cancer Res 2007 13: 488-497 doi: 10.1158/1078-0432.CCR-06-1842 [Abstract] [Full Text] [PDF] Supplementary Data  

Multiple Gene Expression Classifiers from Different Array Platforms Predict Poor Prognosis of Colorectal Cancer

Yu-Hsin Lin, Jan Friederichs, Michael A. Black, Jörg Mages, Robert Rosenberg, Parry J. Guilford, Vicky Phillips, Mark Thompson-Fawcett, Nikola Kasabov, Tumi Toro, Arend E. Merrie, Andre van Rij, Han-Seung Yoon, John L. McCall, Jörg Rüdiger Siewert, Bernhard Holzmann, and Anthony E. Reeve
Clin Cancer Res 2007 13: 498-507 doi: 10.1158/1078-0432.CCR-05-2734 [Abstract] [Full Text] [PDF] Supplementary Data  

Centromere Protein H Is a Novel Prognostic Marker for Nasopharyngeal Carcinoma Progression and Overall Patient Survival

Wen-Ting Liao, Li-Bing Song, Hui-Zhong Zhang, Xing Zhang, Ling Zhang, Wan-Li Liu, Yan Feng, Bao-Hong Guo, Hai-Qiang Mai, Su-Mei Cao, Man-Zhi Li, Hai-De Qin, Yi-Xin Zeng, and Mu-Sheng Zeng
Clin Cancer Res 2007 13: 508-514 doi: 10.1158/1078-0432.CCR-06-1512 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

A Phase I Study of Pemetrexed, Carboplatin, and Concurrent Radiotherapy in Patients with Locally Advanced or Metastatic Non–Small Cell Lung or Esophageal Cancer

Tanguy Y. Seiwert, Philip P. Connell, Ann M. Mauer, Philip C. Hoffman, Christopher M. George, Livia Szeto, Ravi Salgia, Katherine E. Posther, Binh Nguyen, Daniel J. Haraf, and Everett E. Vokes
Clin Cancer Res 2007 13: 515-522 doi: 10.1158/1078-0432.CCR-06-1058 [Abstract] [Full Text] [PDF]  

Phase 1b Dose Escalation Study of Erlotinib in Combination with Infusional 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Advanced Solid Tumors

Axel-R. Hanauske, Jim Cassidy, Javier Sastre, Claus Bolling, Robert J. Jones, Ashok Rakhit, Scott Fettner, Ulrich Brennscheidt, Andrea Feyereislova, and Eduardo Díaz-Rubio
Clin Cancer Res 2007 13: 523-531 doi: 10.1158/1078-0432.CCR-06-1627 [Abstract] [Full Text] [PDF]  

A Phase I and Pharmacokinetic Study of Pemetrexed Plus Irinotecan in Patients with Advanced Solid Malignancies

Eric K. Rowinsky, Muralidhar Beeram, Lisa A. Hammond, Garry Schwartz, Johann De Bono, Baharam Forouzesh, Quincy Chu, Jane E. Latz, Shengyan Hong, William John, and Binh Nguyen
Clin Cancer Res 2007 13: 532-539 doi: 10.1158/1078-0432.CCR-06-1606 [Abstract] [Full Text] [PDF]  

A Phase I Study of Immunization Using Particle-Mediated Epidermal Delivery of Genes for gp100 and GM-CSF into Uninvolved Skin of Melanoma Patients

Ryan D. Cassaday, Paul M. Sondel, David M. King, Michael D. Macklin, Jacek Gan, Tom F. Warner, Cindy L. Zuleger, Alan J. Bridges, Heidi G. Schalch, Kyung Mann Kim, Jacquelyn A. Hank, David M. Mahvi, and Mark R. Albertini
Clin Cancer Res 2007 13: 540-549 doi: 10.1158/1078-0432.CCR-06-2039 [Abstract] [Full Text] [PDF]  

Regulation of Hepatocyte Growth Factor Activator Inhibitor 2 by Hypoxia in Breast Cancer

Daniele Generali, Stephen B. Fox, Alfredo Berruti, John W. Moore, Maria Pia Brizzi, Nilay Patel, Giovanni Allevi, Simone Bonardi, Sergio Aguggini, Alessandra Bersiga, Leticia Campo, Luigi Dogliotti, Alberto Bottini, and Adrian L. Harris
Clin Cancer Res 2007 13: 550-558 doi: 10.1158/1078-0432.CCR-06-1266 [Abstract] [Full Text] [PDF]  

Cumulative Incidence in Competing Risks Data and Competing Risks Regression Analysis

Haesook T. Kim
Clin Cancer Res 2007 13: 559-565 doi: 10.1158/1078-0432.CCR-06-1210 [Abstract] [Full Text] [PDF]  

Antigenic Profiling of Glioma Cells to Generate Allogeneic Vaccines or Dendritic Cell–Based Therapeutics

Jian Gang Zhang, Junichi Eguchi, Carol A. Kruse, German G. Gomez, Habib Fakhrai, Stephanie Schroter, Wenxue Ma, Neil Hoa, Boris Minev, Christina Delgado, H. Terry Wepsic, Hideho Okada, and Martin R. Jadus
Clin Cancer Res 2007 13: 566-575 doi: 10.1158/1078-0432.CCR-06-1576 [Abstract] [Full Text] [PDF]  

Phase I Study of the Farnesyltransferase Inhibitor Lonafarnib with Weekly Paclitaxel in Patients with Solid Tumors

Neal E. Ready, Alan Lipton, Yali Zhu, Paul Statkevich, Emily Frank, Dolores Curtis, and Ronald M. Bukowski
Clin Cancer Res 2007 13: 576-583 doi: 10.1158/1078-0432.CCR-06-1262 [Abstract] [Full Text] [PDF]  

Phase I Clinical Trial of STA-4783 in Combination with Paclitaxel in Patients with Refractory Solid Tumors

Anna Berkenblit, Joseph P. Eder, Jr., David P. Ryan, Michael V. Seiden, Noriaki Tatsuta, Matthew L. Sherman, Thomas A. Dahl, Bruce J. Dezube, and Jeffrey G. Supko
Clin Cancer Res 2007 13: 584-590 doi: 10.1158/1078-0432.CCR-06-0964 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

CHIR-124, a Novel Potent Inhibitor of Chk1, Potentiates the Cytotoxicity of Topoisomerase I Poisons In vitro and In vivo

Archie N. Tse, Katherine G. Rendahl, Tahir Sheikh, Haider Cheema, Kim Aardalen, Millicent Embry, Sylvia Ma, Edward J. Moler, Zhi Jie Ni, Daniel E. Lopes de Menezes, Barbara Hibner, Thomas G. Gesner, and Gary K. Schwartz
Clin Cancer Res 2007 13: 591-602 doi: 10.1158/1078-0432.CCR-06-1424 [Abstract] [Full Text] [PDF] Supplementary Data  

Copper-67 Radioimmunotherapy and Growth Inhibition by Anti–L1-Cell Adhesion Molecule Monoclonal Antibodies in a Therapy Model of Ovarian Cancer Metastasis

Karin Knogler, Jürgen Grünberg, Kurt Zimmermann, Susan Cohrs, Michael Honer, Simon Ametamey, Peter Altevogt, Mina Fogel, P. August Schubiger, and Ilse Novak-Hofer
Clin Cancer Res 2007 13: 603-611 doi: 10.1158/1078-0432.CCR-06-1486 [Abstract] [Full Text] [PDF]  

Human Glioma Cell Sensitivity to the Sequence-Specific Alkylating Agent Methyl-Lexitropsin

Michael S. Bobola, Sridhar Varadarajan, Nolan W. Smith, Ryan D. Goff, Douglas D. Kolstoe, A. Blank, Barry Gold, and John R. Silber
Clin Cancer Res 2007 13: 612-620 doi: 10.1158/1078-0432.CCR-06-1127 [Abstract] [Full Text] [PDF]  

The Bcl-2 Family Protein Inhibitor, ABT-737, Has Substantial Antimyeloma Activity and Shows Synergistic Effect with Dexamethasone and Melphalan

Suzanne Trudel, A. Keith Stewart, Zhihua Li, Yanjun Shu, Sheng-Ben Liang, Young Trieu, Donna Reece, Josh Paterson, Dingyan Wang, and Xiao-Yan Wen
Clin Cancer Res 2007 13: 621-629 doi: 10.1158/1078-0432.CCR-06-1526 [Abstract] [Full Text] [PDF]  

Glucocorticoids Modulate Tumor Radiation Response through a Decrease in Tumor Oxygen Consumption

Nathalie Crokart, Bénédicte F. Jordan, Christine Baudelet, Gregory O. Cron, Julie Hotton, Kim Radermacher, Vincent Grégoire, Nelson Beghein, Philippe Martinive, Caroline Bouzin, Olivier Feron, and Bernard Gallez
Clin Cancer Res 2007 13: 630-635 doi: 10.1158/1078-0432.CCR-06-0802 [Abstract] [Full Text] [PDF]  

Early Detection and Rapid Isolation of Leukemia-Reactive Donor T Cells for Adoptive Transfer Using the IFN- Secretion Assay

Inge Jedema, Pauline Meij, Esther Steeneveld, Mels Hoogendoorn, Bart A. Nijmeijer, Marian van de Meent, Simone A.P. van Luxemburg-Heijs, Roel Willemze, and J.H. Frederik Falkenburg
Clin Cancer Res 2007 13: 636-643 doi: 10.1158/1078-0432.CCR-06-2093 [Abstract] [Full Text] [PDF]  

Cyclophosphamide Enhances the Antitumor Efficacy of Adoptively Transferred Immune Cells through the Induction of Cytokine Expression, B-Cell and T-Cell Homeostatic Proliferation, and Specific Tumor Infiltration

Laura Bracci, Federica Moschella, Paola Sestili, Valentina La Sorsa, Mara Valentini, Irene Canini, Sara Baccarini, Sonia Maccari, Carlo Ramoni, Filippo Belardelli, and Enrico Proietti
Clin Cancer Res 2007 13: 644-653 doi: 10.1158/1078-0432.CCR-06-1209 [Abstract] [Full Text] [PDF]  

Cancer Prevention:

Reduced Mammographic Density with Use of a Gonadotropin-Releasing Hormone Agonist–Based Chemoprevention Regimen in BRCA1 Carriers

Jeffrey N. Weitzel, Saundra S. Buys, William H. Sherman, Anna Marie Daniels, Giske Ursin, John R. Daniels, Deborah J. MacDonald, Kathleen R. Blazer, Malcolm C. Pike, and Darcy V. Spicer
Clin Cancer Res 2007 13: 654-658 doi: 10.1158/1078-0432.CCR-06-1902 [Abstract] [Full Text] [PDF]  

Cyclin A Immunocytology as a Risk Stratification Tool for Barrett's Esophagus Surveillance

Pierre Lao-Sirieix, Laurence Lovat, and Rebecca C. Fitzgerald
Clin Cancer Res 2007 13: 659-665 doi: 10.1158/1078-0432.CCR-06-1385 [Abstract] [Full Text] [PDF]  

Innovations and Challenges in Renal Cancer:

Innovations and Challenges in Renal Cell Carcinoma: Summary Statement from the Second Cambridge Conference

Michael B. Atkins, Marc S. Ernstoff, Robert A. Figlin, Keith T. Flaherty, Daniel J. George, William G. Kaelin, Jr., Eugene D. Kwon, Towia A. Libermann, W. Marston Linehan, David F. McDermott, Augusto C. Ochoa, Allan J. Pantuck, Brian I. Rini, Mark A. Rosen, Jeffrey A. Sosman, Vikas P. Sukhatme, Johannes W. Vieweg, Christopher G. Wood, and Laura King
Clin Cancer Res 2007 13: 667s-670s doi: 10.1158/1078-0432.CCR-06-2231 [Abstract] [Full Text] [PDF]  

Identification of the Genes for Kidney Cancer: Opportunity for Disease-Specific Targeted Therapeutics

W. Marston Linehan, Peter A. Pinto, Ramaprasad Srinivasan, Maria Merino, Peter Choyke, Lynda Choyke, Jonathan Coleman, Jorge Toro, Gladys Glenn, Cathy Vocke, Bert Zbar, Laura S. Schmidt, Donald Bottaro, and Len Neckers
Clin Cancer Res 2007 13: 671s-679s doi: 10.1158/1078-0432.CCR-06-1870 [Abstract] [Full Text] [PDF]  

The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma

William G. Kaelin, Jr.
Clin Cancer Res 2007 13: 680s-684s doi: 10.1158/1078-0432.CCR-06-1865 [Abstract] [Full Text] [PDF]  

Genomics of Renal Cell Cancer: The Biology Behind and the Therapy Ahead

Jon Jones and Towia A. Libermann
Clin Cancer Res 2007 13: 685s-692s doi: 10.1158/1078-0432.CCR-06-1867 [Abstract] [Full Text] [PDF]  

Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma: Is It Still Imperative in the Era of Targeted Therapy?

Allan J. Pantuck, Arie S. Belldegrun, and Robert A. Figlin
Clin Cancer Res 2007 13: 693s-696s doi: 10.1158/1078-0432.CCR-06-1916 [Abstract] [Full Text] [PDF]  

Multimodal Approaches in the Management of Locally Advanced and Metastatic Renal Cell Carcinoma: Combining Surgery and Systemic Therapies to Improve Patient Outcome

Christopher G. Wood
Clin Cancer Res 2007 13: 697s-702s doi: 10.1158/1078-0432.CCR-06-2109 [Abstract] [Full Text] [PDF]  

Protein Expression Profiles in Renal Cell Carcinoma: Staging, Prognosis, and Patient Selection for Clinical Trials

John S. Lam, Allan J. Pantuck, Arie S. Belldegrun, and Robert A. Figlin
Clin Cancer Res 2007 13: 703s-708s doi: 10.1158/1078-0432.CCR-06-1864 [Abstract] [Full Text] [PDF]  

Implications of B7-H1 Expression in Clear Cell Carcinoma of the Kidney for Prognostication and Therapy

R. Houston Thompson, Haidong Dong, and Eugene D. Kwon
Clin Cancer Res 2007 13: 709s-715s doi: 10.1158/1078-0432.CCR-06-1868 [Abstract] [Full Text] [PDF]  

Update on the Application of Interleukin-2 in the Treatment of Renal Cell Carcinoma

David F. McDermott
Clin Cancer Res 2007 13: 716s-720s doi: 10.1158/1078-0432.CCR-06-1872 [Abstract] [Full Text] [PDF]  

Arginase, Prostaglandins, and Myeloid-Derived Suppressor Cells in Renal Cell Carcinoma

Augusto C. Ochoa, Arnold H. Zea, Claudia Hernandez, and Paulo C. Rodriguez
Clin Cancer Res 2007 13: 721s-726s doi: 10.1158/1078-0432.CCR-06-2197 [Abstract] [Full Text] [PDF]  

Reversal of Tumor-Mediated Immunosuppression

Johannes Vieweg, Zhen Su, Philipp Dahm, and Sergei Kusmartsev
Clin Cancer Res 2007 13: 727s-732s doi: 10.1158/1078-0432.CCR-06-1924 [Abstract] [Full Text] [PDF]  

Developing a Rational Tumor Vaccine Therapy for Renal Cell Carcinoma: Immune Yin and Yang

Marc S. Ernstoff, Todd S. Crocenzi, John D. Seigne, Nancy A. Crosby, Bernard F. Cole, Jan L. Fisher, Jill C. Uhlenhake, Diane Mellinger, Cathy Foster, Conrad J. Farnham, Kathleen Mackay, Zbigniew M. Szczepiorkowski, Susan M. Webber, Alan R. Schned, Robert D. Harris, Richard J. Barth, Jr., John A. Heaney, and Randolph J. Noelle
Clin Cancer Res 2007 13: 733s-740s doi: 10.1158/1078-0432.CCR-06-2064 [Abstract] [Full Text] [PDF]  

Biological Aspects and Binding Strategies of Vascular Endothelial Growth Factor in Renal Cell Carcinoma

Brian I. Rini and W.Kimryn Rathmell
Clin Cancer Res 2007 13: 741s-746s doi: 10.1158/1078-0432.CCR-06-2110 [Abstract] [Full Text] [PDF]  

Sorafenib in Renal Cell Carcinoma

Keith T. Flaherty
Clin Cancer Res 2007 13: 747s-752s doi: 10.1158/1078-0432.CCR-06-2063 [Abstract] [Full Text] [PDF]  

Phase 2 Studies of Sunitinib and AG013736 in Patients with Cytokine-Refractory Renal Cell Carcinoma

Daniel J. George
Clin Cancer Res 2007 13: 753s-757s doi: 10.1158/1078-0432.CCR-06-2044 [Abstract] [Full Text] [PDF]  

The Role of Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cancer

Daniel Cho, Sabina Signoretti, Meredith Regan, James W. Mier, and Michael B. Atkins
Clin Cancer Res 2007 13: 758s-763s doi: 10.1158/1078-0432.CCR-06-1986 [Abstract] [Full Text] [PDF]  

Opportunities and Obstacles to Combination Targeted Therapy in Renal Cell Cancer

Jeffrey A. Sosman, Igor Puzanov, and Michael B. Atkins
Clin Cancer Res 2007 13: 764s-769s doi: 10.1158/1078-0432.CCR-06-1975 [Abstract] [Full Text] [PDF]  

Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Assessing Tumor Vascularity and Vascular Effects of Targeted Therapies in Renal Cell Carcinoma

Mark A. Rosen and Mitchell D. Schnall
Clin Cancer Res 2007 13: 770s-776s doi: 10.1158/1078-0432.CCR-06-1921 [Abstract] [Full Text] [PDF]  

Biomarkers for Monitoring Antiangiogenic Therapy

Rupal S. Bhatt, Pankaj Seth, and Vikas P. Sukhatme
Clin Cancer Res 2007 13: 777s-780s doi: 10.1158/1078-0432.CCR-06-1922 [Abstract] [Full Text] [PDF]  

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