Editorials:

Survival of Patients with Clinical Stage I Lung Cancer Diagnosed by Computed Tomography Screening for Lung Cancer

Claudia I. Henschke for the International Early Lung Cancer Action Program Investigators
Clin Cancer Res 2007 13: 4949-4950 doi: 10.1158/1078-0432.CCR-07-0317 [Full Text] [PDF]  

CT Screening for Lung Cancer: Are We Ready for Wide-Scale Application?

Joseph Aisner
Clin Cancer Res 2007 13: 4951-4953 doi: 10.1158/1078-0432.CCR-07-0315 [Full Text] [PDF]  

Epidermal Growth Factor Receptor Mutation Testing in Lung Cancer: Searching for the Ideal Method

William Pao and Marc Ladanyi
Clin Cancer Res 2007 13: 4954-4955 doi: 10.1158/1078-0432.CCR-07-1387 [Full Text] [PDF]  

The Biology Behind:

Inhibitor-B Kinase in Tumor Promotion and Suppression During Progression of Squamous Cell Carcinoma

Carter Van Waes, Ming Yu, Liesl Nottingham, and Michael Karin
Clin Cancer Res 2007 13: 4956 -4959 doi: 10.1158/1078-0432.CCR-07-1287 [Full Text] [PDF]  

Molecular Pathways:

Targeting the Limitless Replicative Potential of Cancer: The Telomerase/Telomere Pathway

Lloyd Kelland
Clin Cancer Res 2007 13: 4960-4963 doi: 10.1158/1078-0432.CCR-07-0422 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Dissecting the Akt/Mammalian Target of Rapamycin Signaling Network: Emerging Results from the Head and Neck Cancer Tissue Array Initiative

Alfredo A. Molinolo, Stephen M. Hewitt, Panomwat Amornphimoltham, Somboon Keelawat, Samraeung Rangdaeng, Abelardo Meneses García, Ana R. Raimondi, Rafael Jufe, María Itoiz, Yan Gao, Dhananjaya Saranath, George S. Kaleebi, George H. Yoo, Lee Leak, Ernest M. Myers, Satoru Shintani, David Wong, H. Davis Massey, W. Andrew Yeudall, Fulvio Lonardo, John Ensley, and J. Silvio Gutkind
Clin Cancer Res 2007 13: 4964-4973 doi: 10.1158/1078-0432.CCR-07-1041 [Abstract] [Full Text] [PDF]  

Rapid Detection of Epidermal Growth Factor Receptor Mutations in Lung Cancer by the SMart-Amplification Process

Kanako Hoshi, Hideki Takakura, Yasumasa Mitani, Kenji Tatsumi, Nobuyoshi Momiyama, Yasushi Ichikawa, Shinji Togo, Toru Miyagi, Yuki Kawai, Yasushi Kogo, Takeshi Kikuchi, Chiaki Kato, Takahiro Arakawa, Syuji Uno, Paul E. Cizdziel, Alexander Lezhava, Noburou Ogawa, Yoshihide Hayashizaki, and Hiroshi Shimada
Clin Cancer Res 2007 13: 4974-4983 doi: 10.1158/1078-0432.CCR-07-0509 [Abstract] [Full Text] [PDF] Supplementary Data  

Is There a Human Homologue to the Murine Proteolysis-Inducing Factor?

Barbara M. Wieland, Grant D. Stewart, Richard J.E. Skipworth, Kathryn Sangster, Kenneth C.H. Fearon, James A. Ross, Tony J. Reiman, Jay Easaw, Marina Mourtzakis, Vishesh Kumar, Brian J. Pak, Kathryn Calder, Gerasimos Filippatos, Dimitris T. Kremastinos, Monica Palcic, and Vickie E. Baracos
Clin Cancer Res 2007 13: 4984-4992 doi: 10.1158/1078-0432.CCR-07-0946 [Abstract] [Full Text] [PDF]  

A New Diagnostic Marker for Secreted Epstein-Barr Virus–Encoded LMP1 and BARF1 Oncoproteins in the Serum and Saliva of Patients with Nasopharyngeal Carcinoma

Karim Houali, Xiaohui Wang, Yuko Shimizu, Djamel Djennaoui, John Nicholls, Sylvie Fiorini, Abdelmadjid Bouguermouh, and Tadamasa Ooka
Clin Cancer Res 2007 13: 4993-5000 doi: 10.1158/1078-0432.CCR-06-2945 [Abstract] [Full Text] [PDF]  

Isolation and Molecular Profiling of Bone Marrow Micrometastases Identifies TWIST1 as a Marker of Early Tumor Relapse in Breast Cancer Patients

Mark A. Watson, Lourdes R. Ylagan, Kathryn M. Trinkaus, William E. Gillanders, Michael J. Naughton, Katherine N. Weilbaecher, Timothy P. Fleming, and Rebecca L. Aft
Clin Cancer Res 2007 13: 5001-5009 doi: 10.1158/1078-0432.CCR-07-0024 [Abstract] [Full Text] [PDF] Supplementary Data  

Melanoma Cells Exhibit Variable Signal Transducer and Activator of Transcription 1 Phosphorylation and a Reduced Response to IFN- Compared with Immune Effector Cells

Gregory B. Lesinski, John Trefry, Melanie Brasdovich, Sri Vidya Kondadasula, Korkor Sackey, Jason M. Zimmerer, Abhik Ray Chaudhury, Lianbo Yu, Xiaoli Zhang, Tim R. Crespin, Michael J. Walker, and William E. Carson, III
Clin Cancer Res 2007 13: 5010-5019 doi: 10.1158/1078-0432.CCR-06-3092 [Abstract] [Full Text] [PDF] Supplementary Data  

Monocyte Chemotactic Protein-1 Secreted by Primary Breast Tumors Stimulates Migration of Mesenchymal Stem Cells

R.M. Dwyer, S.M. Potter-Beirne, K.A. Harrington, A.J. Lowery, E. Hennessy, J.M. Murphy, F.P. Barry, T. O'Brien, and M.J. Kerin
Clin Cancer Res 2007 13: 5020-5027 doi: 10.1158/1078-0432.CCR-07-0731 [Abstract] [Full Text] [PDF]  

Deletion of a Small Consensus Region at 6q15, Including the MAP3K7 Gene, Is Significantly Associated with High-Grade Prostate Cancers

Wennuan Liu, Bao-Li Chang, Scott Cramer, Patrick P. Koty, Tao Li, Jishan Sun, Aubrey R. Turner, Chris Von Kap-Herr, Peggy Bobby, Jianyu Rao, S. Lilly Zheng, William B. Isaacs, and Jianfeng Xu
Clin Cancer Res 2007 13: 5028-5033 doi: 10.1158/1078-0432.CCR-07-0300 [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 and Platelet-Derived Growth Factor Receptors as Potential Targets in Treating Aggressive Fibromatosis

Stefano Signoroni, Milo Frattini, Tiziana Negri, Elisa Pastore, Elena Tamborini, Paola Casieri, Marta Orsenigo, Luca Da Riva, Paolo Radice, Paola Sala, Alessandro Gronchi, Lucio Bertario, Marco A. Pierotti, and Silvana Pilotti
Clin Cancer Res 2007 13: 5034-5040 doi: 10.1158/1078-0432.CCR-07-0336 [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Epigenetic Inactivation of IB Kinase- in Oral Carcinomas and Tumor Progression

Genta Maeda, Tadashige Chiba, Shuichi Kawashiri, Tazuko Satoh, and Kazushi Imai
Clin Cancer Res 2007 13: 5041-5047 doi: 10.1158/1078-0432.CCR-07-0463 [Abstract] [Full Text] [PDF]  

Inactivation of HOXA Genes by Hypermethylation in Myeloid and Lymphoid Malignancy is Frequent and Associated with Poor Prognosis

Gordon Strathdee, Tessa L. Holyoake, Alyson Sim, Anton Parker, David G. Oscier, Junia V. Melo, Stefan Meyer, Tim Eden, Anne M. Dickinson, Joanne C. Mountford, Heather G. Jorgensen, Richard Soutar, and Robert Brown
Clin Cancer Res 2007 13: 5048-5055 doi: 10.1158/1078-0432.CCR-07-0919 [Abstract] [Full Text] [PDF] Supplementary Data  

CXCL12 G801A Polymorphism Is a Risk Factor for Sporadic Prostate Cancer Susceptibility

Hiroshi Hirata, Yuji Hinoda, Nobuyuki Kikuno, Ken Kawamoto, Angela V. Dahiya, Yutaka Suehiro, Yuichiro Tanaka, and Rajvir Dahiya
Clin Cancer Res 2007 13: 5056-5062 doi: 10.1158/1078-0432.CCR-07-0859 [Abstract] [Full Text] [PDF]  

Long-term Evaluation of Three Multiple-Case Waldenström Macroglobulinemia Families

Mary L. McMaster, Gyorgy Csako, Therese R. Giambarresi, Linda Vasquez, Melissa Berg, Stephanie Saddlemire, Benjamin Hulley, and Margaret A. Tucker
Clin Cancer Res 2007 13: 5063-5069 doi: 10.1158/1078-0432.CCR-07-0299 [Abstract] [Full Text] [PDF]  

Overexpression of FLIP_L Is an Independent Marker of Poor Prognosis in Colorectal Cancer Patients

Gustave J. Ullenhag, Abhik Mukherjee, Nicholas F.S. Watson, Ahmad H. Al-Attar, John H. Scholefield, and Lindy G. Durrant
Clin Cancer Res 2007 13: 5070-5075 doi: 10.1158/1078-0432.CCR-06-2547 [Abstract] [Full Text] [PDF]  

Clinical Significance of Serum Mesothelin in Patients with Mesothelioma and Lung Cancer

Alfonso Cristaudo, Rudy Foddis, Agnese Vivaldi, Giovanni Guglielmi, Nicola Dipalma, Rosangela Filiberti, Monica Neri, Marcello Ceppi, Michela Paganuzzi, Gian Paolo Ivaldi, Manlio Mencoboni, Pier Aldo Canessa, Nicolino Ambrosino, Antonio Chella, Luciano Mutti, and Riccardo Puntoni
Clin Cancer Res 2007 13: 5076-5081 doi: 10.1158/1078-0432.CCR-07-0629 [Abstract] [Full Text] [PDF]  

Classification Based on the Combination of Molecular and Pathologic Predictors is Superior to Molecular Classification on Prognosis in Colorectal Carcinoma

Fangying Xu, Fenjuan Wang, Meijuan Di, Qiong Huang, Min Wang, Hu Hu, Yisen Jin, Jiankang Dong, and Maode Lai
Clin Cancer Res 2007 13: 5082-5088 doi: 10.1158/1078-0432.CCR-07-0597 [Abstract] [Full Text] [PDF]  

Association Between Hypermethylated Tumor and Paired Surgical Margins in Head and Neck Squamous Cell Carcinomas

Tiziana Martone, Anna Gillio-Tos, Laura De Marco, Valentina Fiano, Milena Maule, Andrea Cavalot, Massimiliano Garzaro, Franco Merletti, and Giorgio Cortesina
Clin Cancer Res 2007 13: 5089-5094 doi: 10.1158/1078-0432.CCR-07-0119 [Abstract] [Full Text] [PDF]  

Methylation of Tumor-Related Genes in Neoadjuvant-Treated Gastric Cancer: Relation to Therapy Response and Clinicopathologic and Molecular Features

Rudolf Napieralski, Katja Ott, Markus Kremer, Karen Becker, Anne-Laure Boulesteix, Florian Lordick, Jörg Rüdiger Siewert, Heinz Höfler, and Gisela Keller
Clin Cancer Res 2007 13: 5095-5102 doi: 10.1158/1078-0432.CCR-07-0241 [Abstract] [Full Text] [PDF]  

Detection of TMPRSS2-ERG Fusion Transcripts and Prostate Cancer Antigen 3 in Urinary Sediments May Improve Diagnosis of Prostate Cancer

Daphne Hessels, Frank P. Smit, Gerald W. Verhaegh, J. Alfred Witjes, Erik B. Cornel, and Jack A. Schalken
Clin Cancer Res 2007 13: 5103-5108 doi: 10.1158/1078-0432.CCR-07-0700 [Abstract] [Full Text] [PDF]  

Overexpression of Apollon, an Antiapoptotic Protein, Is Associated with Poor Prognosis in Childhood De novo Acute Myeloid Leukemia

Ki Woong Sung, Jaewon Choi, Yu Kyeong Hwang, Sang Jin Lee, Hee-Jin Kim, Soo Hyun Lee, Keon Hee Yoo, Hye Lim Jung, and Hong Hoe Koo
Clin Cancer Res 2007 13: 5109-5114 doi: 10.1158/1078-0432.CCR-07-0693 [Abstract] [Full Text] [PDF]  

Significance of HER2 Low-Level Copy Gain in Barrett's Cancer: Implications for Fluorescence In situ Hybridization Testing in Tissues

Sandra Rauser, Roland Weis, Herbert Braselmann, Marcus Feith, Hubert J. Stein, Rupert Langer, Peter Hutzler, Michael Hausmann, Silke Lassmann, Jörg Rüdiger Siewert, Heinz Höfler, Martin Werner, and Axel Walch
Clin Cancer Res 2007 13: 5115-5123 doi: 10.1158/1078-0432.CCR-07-0465 [Abstract] [Full Text] [PDF]  

Age-Related EBV-Associated B-Cell Lymphoproliferative Disorders Constitute a Distinct Clinicopathologic Group: A Study of 96 Patients

Takashi Oyama, Kazuhito Yamamoto, Naoko Asano, Aya Oshiro, Ritsuro Suzuki, Yoshitoyo Kagami, Yasuo Morishima, Kengo Takeuchi, Toshiyuki Izumo, Shigeo Mori, Koichi Ohshima, Junji Suzumiya, Naoya Nakamura, Masafumi Abe, Koichi Ichimura, Yumiko Sato, Tadashi Yoshino, Tomoki Naoe, Yoshie Shimoyama, Yoshikazu Kamiya, Tomohiro Kinoshita, and Shigeo Nakamura
Clin Cancer Res 2007 13: 5124-5132 doi: 10.1158/1078-0432.CCR-06-2823 [Abstract] [Full Text] [PDF] Supplementary Data  

Cancer Therapy: Clinical:

Augmented HER-2–Specific Immunity during Treatment with Trastuzumab and Chemotherapy

Clare Taylor, Dawn Hershman, Nina Shah, Nicole Suciu-Foca, Dan P. Petrylak, Robert Taub, Linda Vahdat, Bin Cheng, Mark Pegram, Keith L. Knutson, and Raphael Clynes
Clin Cancer Res 2007 13: 5133-5143 doi: 10.1158/1078-0432.CCR-07-0507 [Abstract] [Full Text] [PDF]  

Phase I Study of SS1P, a Recombinant Anti-Mesothelin Immunotoxin Given as a Bolus I.V. Infusion to Patients with Mesothelin-Expressing Mesothelioma, Ovarian, and Pancreatic Cancers

Raffit Hassan, Susie Bullock, Ahalya Premkumar, Robert J. Kreitman, Hedy Kindler, Mark C. Willingham, and Ira Pastan
Clin Cancer Res 2007 13: 5144-5149 doi: 10.1158/1078-0432.CCR-07-0869 [Abstract] [Full Text] [PDF]  

Prospective Assessment of Discontinuation and Reinitiation of Erlotinib or Gefitinib in Patients with Acquired Resistance to Erlotinib or Gefitinib Followed by the Addition of Everolimus

Gregory J. Riely, Mark G. Kris, Binsheng Zhao, Tim Akhurst, Daniel T. Milton, Erin Moore, Leslie Tyson, William Pao, Naiyer A. Rizvi, Lawrence H. Schwartz, and Vincent A. Miller
Clin Cancer Res 2007 13: 5150-5155 doi: 10.1158/1078-0432.CCR-07-0560 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Inherited Variation in Hormone-Regulating Genes and Prostate Cancer Survival

Sara Lindström, Hans-Olov Adami, Katarina Augustsson Bälter, Jianfeng Xu, S. Lilly Zheng, Pär Stattin, Henrik Grönberg, and Fredrik Wiklund
Clin Cancer Res 2007 13: 5156-5161 doi: 10.1158/1078-0432.CCR-07-0669 [Abstract] [Full Text] [PDF]  

Resveratrol Inhibits Tumor Growth of Human Neuroblastoma and Mediates Apoptosis by Directly Targeting Mitochondria

Paul R. van Ginkel, Dhruv Sareen, Lalita Subramanian, Quintisha Walker, Soesiawati R. Darjatmoko, Mary J. Lindstrom, Amol Kulkarni, Daniel M. Albert, and Arthur S. Polans
Clin Cancer Res 2007 13: 5162-5169 doi: 10.1158/1078-0432.CCR-07-0347 [Abstract] [Full Text] [PDF]  

The Intestinotrophic Peptide, GLP-2, Counteracts Intestinal Atrophy in Mice Induced by the Epidermal Growth Factor Receptor Inhibitor, Gefitinib

Kristine Juul Hare, Bolette Hartmann, Hannelouise Kissow, Jens Juul Holst, and Steen Seier Poulsen
Clin Cancer Res 2007 13: 5170-5175 doi: 10.1158/1078-0432.CCR-07-0574 [Abstract] [Full Text] [PDF]  

Chemoprevention of Carcinogenic Progression to Esophageal Adenocarcinoma by the Manganese Superoxide Dismutase Supplementation

Robert C.G. Martin, Qiaohong Liu, John M. Wo, Mukunda B. Ray, and Yan Li
Clin Cancer Res 2007 13: 5176-5182 doi: 10.1158/1078-0432.CCR-07-1152 [Abstract] [Full Text] [PDF]  

Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo

Joell J. Gills, Jaclyn LoPiccolo, Junji Tsurutani, Robert H. Shoemaker, Carolyn J.M. Best, Mones S. Abu-Asab, Jennifer Borojerdi, Noel A. Warfel, Erin R. Gardner, Matthew Danish, M. Christine Hollander, Shigeru Kawabata, Maria Tsokos, William D. Figg, Patricia S. Steeg, and Phillip A. Dennis
Clin Cancer Res 2007 13: 5183-5194 doi: 10.1158/1078-0432.CCR-07-0161 [Abstract] [Full Text] [PDF] Supplementary Data  

Enhanced Survival and Cure of F98 Glioma–Bearing Rats following Intracerebral Delivery of Carboplatin in Combination with Photon Irradiation

Julia Rousseau, Caroline Boudou, Rolf F. Barth, Jacques Balosso, François Estève, and Hélène Elleaume
Clin Cancer Res 2007 13: 5195-5201 Published Online First August 28, 2007. doi: 10.1158/1078-0432.CCR-07-1002 [Abstract] [Full Text] [PDF]  

Targeting Lymphotoxin ß Receptor with Tumor-Specific T Lymphocytes for Tumor Regression

Dafeng Yang, Najam ud Din, Darren D. Browning, Scott I. Abrams, and Kebin Liu
Clin Cancer Res 2007 13: 5202-5210 doi: 10.1158/1078-0432.CCR-07-1161 [Abstract] [Full Text] [PDF]  

Radiation-Enhanced Vascular Targeting of Human Lung Cancers in Mice with a Monoclonal Antibody That Binds Anionic Phospholipids

Jin He, Troy A. Luster, and Philip E. Thorpe
Clin Cancer Res 2007 13: 5211-5218 doi: 10.1158/1078-0432.CCR-07-0793 [Abstract] [Full Text] [PDF]  

Decitabine Up-regulates S100A2 Expression and Synergizes with IFN- to Kill Uveal Melanoma Cells

Jared A. Gollob and Catherine J. Sciambi
Clin Cancer Res 2007 13: 5219-5225 doi: 10.1158/1078-0432.CCR-07-0816 [Abstract] [Full Text] [PDF]  

Corrections:

Article on Use of Single-Dose Intrapleural IFN-ß gene Transfer for Malignant Pleural Mesothelioma and Metastatic Pleural Effusions

Clin Cancer Res 2007 13: 5226 doi: 10.1158/1078-0432.CCR-13-17-COR1 [Full Text] [PDF]  

Article on Peptide Epitopes from the Wilms' Tumor 1 Oncoprotein

Clin Cancer Res 2007 13: 5226 doi: 10.1158/1078-0432.CCR-13-17-COR2 [Full Text] [PDF]  

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