Molecular Pathways:

Pathways Targeting Tumor Lymphangiogenesis

Christoph Wissmann and Michael Detmar
Clin Cancer Res 2006 12: 6865-6868. [Abstract] [Full Text] [PDF]  

Reviews:

Aurora Kinases: New Targets for Cancer Therapy

Richard D. Carvajal, Archie Tse, and Gary K. Schwartz
Clin Cancer Res 2006 12: 6869-6875. [Abstract] [Full Text] [PDF]  

Chelators at the Cancer Coalface: Desferrioxamine to Triapine and Beyond

Yu Yu, Jacky Wong, David B. Lovejoy, Danuta S. Kalinowski, and Des R. Richardson
Clin Cancer Res 2006 12: 6876-6883. [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Lymphokine-Activated Killer T-Cell-Originated Protein Kinase Phosphorylation of Histone H2AX Prevents Arsenite-Induced Apoptosis in RPMI7951 Melanoma Cells

Tatyana A. Zykova, Feng Zhu, Chengrong Lu, LeeAnn Higgins, Yasuaki Tatsumi, Yasuhito Abe, Ann M. Bode, and Zigang Dong
Clin Cancer Res 2006 12: 6884-6893. [Abstract] [Full Text] [PDF]  

Expression of Erythropoietin and Erythropoietin Receptor in Cervical Cancer and Relationship to Survival, Hypoxia, and Apoptosis

Cornelia Leo, Lars-Christian Horn, Cora Rauscher, Bettina Hentschel, Andre Liebmann, Guido Hildebrandt, and Michael Höckel
Clin Cancer Res 2006 12: 6894-6900. [Abstract] [Full Text] [PDF]  

Increased Frequency of CD4⁺ Cells Expressing CD161 in Cancer Patients

Eleni G. Iliopoulou, Michalis V. Karamouzis, Ioannis Missitzis, Alexandros Ardavanis, Nectaria N. Sotiriadou, Constantin N. Baxevanis, Gerasimos Rigatos, Michael Papamichail, and Sonia A. Perez
Clin Cancer Res 2006 12: 6901-6909. [Abstract] [Full Text] [PDF]  

Regulation of Angiogenesis by Id-1 through Hypoxia-Inducible Factor-1–Mediated Vascular Endothelial Growth Factor Up-regulation in Hepatocellular Carcinoma

Terence K. Lee, Ronnie T.P. Poon, Anthony P. Yuen, Ming Tat Ling, Xiang Hong Wang, Yong Chuan Wong, Xin Yuan Guan, Kwan Man, Zao You Tang, and Sheung Tat Fan
Clin Cancer Res 2006 12: 6910-6919. [Abstract] [Full Text] [PDF]  

Molecular and Biochemical Analyses of Platelet-Derived Growth Factor Receptor (PDGFR) B, PDGFRA, and KIT Receptors in Chordomas

Elena Tamborini, Francesca Miselli, Tiziana Negri, M. Stefania Lagonigro, Samantha Staurengo, Gian Paolo Dagrada, Silvia Stacchiotti, Elisa Pastore, Alessandro Gronchi, Federica Perrone, Antonino Carbone, Marco A. Pierotti, Paolo G. Casali, and Silvana Pilotti
Clin Cancer Res 2006 12: 6920-6928. [Abstract] [Full Text] [PDF]  

Implication of Polycomb Members Bmi-1, Mel-18, and Hpc-2 in the Regulation of p16INK4a, p14ARF, h-TERT, and c-Myc Expression in Primary Breast Carcinomas

Javier Silva, José M. García, Cristina Peña, Vanesa García, Gemma Domínguez, Dolores Suárez, Francisca I. Camacho, Ruth Espinosa, Mariano Provencio, Pilar España, and Félix Bonilla
Clin Cancer Res 2006 12: 6929-6936. [Abstract] [Full Text] [PDF]  

Gene Expression Profiling Separates Chromophobe Renal Cell Carcinoma from Oncocytoma and Identifies Vesicular Transport and Cell Junction Proteins as Differentially Expressed Genes

Stephen Rohan, Jiangling J. Tu, Jean Kao, Piali Mukherjee, Fabien Campagne, Xi K. Zhou, Elizabeth Hyjek, Miguel A. Alonso, and Yao-Tseng Chen
Clin Cancer Res 2006 12: 6937-6945. [Abstract] [Full Text] [PDF]  

Detection of Human Papillomavirus and Relevant Tumor Suppressors and Oncoproteins in Laryngeal Tumors

María E. Manjarrez, Rodolfo Ocadiz, Leticia Valle, Cesar Pacheco, Alberto Marroquin, Carlos De la Torre, Moisés Selman, and Patricio Gariglio
Clin Cancer Res 2006 12: 6946-6951. [Abstract] [Full Text] [PDF]  

Sorting Nexin 1 Down-Regulation Promotes Colon Tumorigenesis

Lananh N. Nguyen, Matthew S. Holdren, Anthony P. Nguyen, Momoko H. Furuya, Michele Bianchini, Estrella Levy, José Mordoh, Annie Liu, Gabriela D. Guncay, Jean S. Campbell, and W. Tony Parks
Clin Cancer Res 2006 12: 6952-6959. [Abstract] [Full Text] [PDF] Supplementary Data  

Dysregulated Expression of Stem Cell Factor Bmi1 in Precancerous Lesions of the Gastrointestinal Tract

Keisuke Tateishi, Miki Ohta, Fumihiko Kanai, Bayasi Guleng, Yasuo Tanaka, Yoshinari Asaoka, Motohisa Tada, Motoko Seto, Amarsanaa Jazag, Lin Lianjie, Makoto Okamoto, Hiroyuki Isayama, Minoru Tada, Haruhiko Yoshida, Takao Kawabe, and Masao Omata
Clin Cancer Res 2006 12: 6960-6966. [Abstract] [Full Text] [PDF]  

Genetic and Epigenetic Analysis of CHEK2 in Sporadic Breast, Colon, and Ovarian Cancers

Louise H. Williams, David Choong, Sandra A. Johnson, and Ian G. Campbell
Clin Cancer Res 2006 12: 6967-6972. [Abstract] [Full Text] [PDF]  

Tumor Angiogenesis Is Associated with Plasma Levels of Stromal-Derived Factor-1 in Patients with Multiple Myeloma

Sally K. Martin, Andrea L. Dewar, Amanda N. Farrugia, Noemi Horvath, Stan Gronthos, L. Bik To, and Andrew C.W. Zannettino
Clin Cancer Res 2006 12: 6973-6977. [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Correlation between High Vascular Endothelial Growth Factor-A Serum Levels and Treatment Outcome in Patients with Standard-Risk Acute Lymphoblastic Leukemia: A Report from Children's Oncology Group Study CCG-1962

Ioannis A. Avramis, Eduard H. Panosyan, Fred Dorey, John S. Holcenberg, and Vassilios I. Avramis
Clin Cancer Res 2006 12: 6978-6984. [Abstract] [Full Text] [PDF]  

Free DNA and Carcinoembryonic Antigen Serum Levels: An Important Combination for Diagnosis of Colorectal Cancer

Emanuela Flamini, Laura Mercatali, Oriana Nanni, Daniele Calistri, Roberta Nunziatini, Wainer Zoli, Paola Rosetti, Nice Gardini, Arturo Lattuneddu, Giorgio Maria Verdecchia, and Dino Amadori
Clin Cancer Res 2006 12: 6985-6988. [Abstract] [Full Text] [PDF]  

Wnt Antagonist Family Genes as Biomarkers for Diagnosis, Staging, and Prognosis of Renal Cell Carcinoma Using Tumor and Serum DNA

Shinji Urakami, Hiroaki Shiina, Hideki Enokida, Hiroshi Hirata, Ken Kawamoto, Toshifumi Kawakami, Nobuyuki Kikuno, Yuichiro Tanaka, Shahana Majid, Masayuki Nakagawa, Mikio Igawa, and Rajvir Dahiya
Clin Cancer Res 2006 12: 6989-6997. [Abstract] [Full Text] [PDF]  

Expression of Matrix Metalloproteinase-7 on Cancer Cells and Tissue Endothelial Cells in Renal Cell Carcinoma: Prognostic Implications and Clinical Significance for Invasion and Metastasis

Yasuyoshi Miyata, Takahisa Iwata, Kojiro Ohba, Shigeru Kanda, Masaharu Nishikido, and Hiroshi Kanetake
Clin Cancer Res 2006 12: 6998-7003. [Abstract] [Full Text] [PDF]  

Chromosome 20q13.2 Gain May Predict Intravesical Recurrence after Nephroureterectomy in Upper Urinary Tract Urothelial Tumors

Jumpei Akao, Hideyasu Matsuyama, Yoshiaki Yamamoto, Kohsuke Sasaki, and Katsusuke Naito
Clin Cancer Res 2006 12: 7004-7008. [Abstract] [Full Text] [PDF]  

Haplotypes in Matrix Metalloproteinase Gene Cluster on Chromosome 11q22 Contribute to the Risk of Lung Cancer Development and Progression

Tong Sun, Yang Gao, Wen Tan, Sufang Ma, Xuemei Zhang, Yonggang Wang, Qingrun Zhang, Yongli Guo, Dan Zhao, Changqing Zeng, and Dongxin Lin
Clin Cancer Res 2006 12: 7009-7017. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Flt3 Internal Tandem Duplication and P-Glycoprotein Functionality in 171 Patients with Acute Myeloid Leukemia

Christophe Marzac, I. Teyssandier, Ors'Anton Calendini, Jean-Yves Perrot, Anne-Marie Faussat, Ruoping Tang, Nicole Casadevall, Jean-Pierre Marie, and Ollivier Legrand
Clin Cancer Res 2006 12: 7018-7024. [Abstract] [Full Text] [PDF]  

Late Toxicity Is Not Increased in BRCA1/BRCA2 Mutation Carriers Undergoing Breast Radiotherapy in the United Kingdom

Susan Shanley, Kate McReynolds, Audrey Ardern-Jones, Roger Ahern, Indrajit Fernando, John Yarnold, Gareth Evans, Diana Eccles, Shirley Hodgson, Sue Ashley, Linda Ashcroft, Andrew Tutt, Elizabeth Bancroft, Susan Short, Gerald Gui, The Breast Unit of the Royal Marsden NHS Foundation Trust, Lester Barr, Andrew Baildam, Anthony Howell, Gavin Royle, Lori Pierce, Douglas Easton, and Rosalind Eeles
Clin Cancer Res 2006 12: 7025-7032. [Abstract] [Full Text] [PDF]  

Acute Chemotherapy–Related Toxicity Is Not Increased in BRCA1 and BRCA2 Mutation Carriers Treated for Breast Cancer in the United Kingdom

Susan Shanley, Kate McReynolds, Audrey Ardern-Jones, Roger Ahern, Indrajit Fernando, John Yarnold, Gareth Evans, Diana Eccles, Shirley Hodgson, Sue Ashley, Linda Ashcroft, Andrew Tutt, Elizabeth Bancroft, Susan Short, Ian Smith, Gerald Gui, The Breast Unit of the Royal Marsden NHS Foundation Trust, Lester Barr, Andrew Baildam, Anthony Howell, Gavin Royle, Lori Pierce, Douglas Easton, and Rosalind Eeles
Clin Cancer Res 2006 12: 7033-7038. [Abstract] [Full Text] [PDF]  

A Study to Determine the Effects of Food and Multiple Dosing on the Pharmacokinetics of Vorinostat Given Orally to Patients with Advanced Cancer

Eric H. Rubin, Nancy G.B. Agrawal, Evan J. Friedman, Pamela Scott, Kathryn E. Mazina, Linda Sun, Lihong Du, Justin L. Ricker, Stanley R. Frankel, Keith M. Gottesdiener, John A. Wagner, and Marian Iwamoto
Clin Cancer Res 2006 12: 7039-7045. [Abstract] [Full Text] [PDF]  

A Phase 2 Study of Rituximab in Combination with Recombinant Interleukin-2 for Rituximab-Refractory Indolent Non-Hodgkin's Lymphoma

Khuda D. Khan, Christos Emmanouilides, Don M. Benson, Jr., Deborah Hurst, Pablo Garcia, Glenn Michelson, Sandra Milan, Amy K. Ferketich, Lawrence Piro, John P. Leonard, Pierluigi Porcu, Charles F. Eisenbeis, Amy L. Banks, Lei Chen, John C. Byrd, and Michael A. Caligiuri
Clin Cancer Res 2006 12: 7046-7053. [Abstract] [Full Text] [PDF]  

Primary Tumor Levels of Tissue Inhibitor of Metalloproteinases-1 Are Predictive of Resistance to Chemotherapy in Patients with Metastatic Breast Cancer

Anne-Sofie Schrohl, Marion E. Meijer-van Gelder, Mads N. Holten-Andersen, Ib Jarle Christensen, Maxime P. Look, Henning T. Mouridsen, Nils Brünner, and John A. Foekens
Clin Cancer Res 2006 12: 7054-7058. [Abstract] [Full Text] [PDF]  

Phase I Study of Bryostatin 1 and Gemcitabine

Basil F. El-Rayes, Shirish Gadgeel, Anthony F. Shields, Stephanie Manza, Patricia Lorusso, and Philip A. Philip
Clin Cancer Res 2006 12: 7059-7062. [Abstract] [Full Text] [PDF]  

Polymorphisms in Genes Related to Oxidative Stress (CAT, MnSOD, MPO, and eNOS) and Acute Toxicities from Radiation Therapy following Lumpectomy for Breast Cancer

Jiyoung Ahn, Christine B. Ambrosone, Peter A. Kanetsky, Chunqiao Tian, Teresa A. Lehman, Silke Kropp, Irmgard Helmbold, Dietrich von Fournier, Wulf Haase, Marie Luise Sautter-Bihl, Frederik Wenz, and Jenny Chang-Claude
Clin Cancer Res 2006 12: 7063-7070. [Abstract] [Full Text] [PDF] Supplementary Data  

A Phase I Study of Pemetrexed (ALIMTA) and Cyclophosphamide in Patients with Locally Advanced or Metastatic Breast Cancer

Christian Dittrich, Lubos Petruzelka, Pavel Vodvarka, Margit Gneist, Filip Janku, Tamara Kysela, Allen Melemed, Jane Latz, Lorinda Simms, and Kurt Krejcy
Clin Cancer Res 2006 12: 7071-7078. [Abstract] [Full Text] [PDF]  

Modulation of Cell Cycle Progression in Human Tumors: A Pharmacokinetic and Tumor Molecular Pharmacodynamic Study of Cisplatin Plus the Chk1 Inhibitor UCN-01 (NSC 638850)

Raymond P. Perez, Lionel D. Lewis, Andrew P. Beelen, Anthony J. Olszanski, Nicholas Johnston, C. Harker Rhodes, Bernard Beaulieu, Marc S. Ernstoff, and Alan Eastman
Clin Cancer Res 2006 12: 7079-7085. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

In vivo Radioprotection by the Fullerene Nanoparticle DF-1 as Assessed in a Zebrafish Model

Borbala Daroczi, Gabor Kari, Mary Frances McAleer, Jeffrey C. Wolf, Ulrich Rodeck, and Adam P. Dicker
Clin Cancer Res 2006 12: 7086-7091. [Abstract] [Full Text] [PDF]  

Complete Antitumor Protection by Perioperative Immunization with GM3/VSSP Vaccine in a Preclinical Mouse Melanoma Model

Mariano R. Gabri, Zaima Mazorra, Giselle V. Ripoll, Circe Mesa, Luis E. Fernandez, Daniel E. Gomez, and Daniel F. Alonso
Clin Cancer Res 2006 12: 7092-7098. [Abstract] [Full Text] [PDF]  

Synergistic Antitumor Activity of ZD6474, An Inhibitor of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor Signaling, with Gemcitabine and Ionizing Radiation against Pancreatic Cancer

Cataldo Bianco, Elisa Giovannetti, Fortunato Ciardiello, Valentina Mey, Sara Nannizzi, Giampaolo Tortora, Teresa Troiani, Francesco Pasqualetti, Gail Eckhardt, Mario de Liguoro, Simona Ricciardi, Mario Del Tacca, David Raben, Luca Cionini, and Romano Danesi
Clin Cancer Res 2006 12: 7099-7107. [Abstract] [Full Text] [PDF]  

Tumor-Selective Gene Expression in a Hepatic Metastasis Model after Locoregional Delivery of a Replication-Competent Retrovirus Vector

Kei Hiraoka, Takahiro Kimura, Christopher R. Logg, and Noriyuki Kasahara
Clin Cancer Res 2006 12: 7108-7116. [Abstract] [Full Text] [PDF]  

Antitumor Activity of the Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Gefitinib (ZD1839, Iressa) in Non–Small Cell Lung Cancer Cell Lines Correlates with Gene Copy Number and EGFR Mutations but not EGFR Protein Levels

Barbara A. Helfrich, David Raben, Marileila Varella-Garcia, Dan Gustafson, Daniel C. Chan, Lynne Bemis, Chris Coldren, Anna Barón, Chan Zeng, Wilbur A. Franklin, Fred R. Hirsch, Adi Gazdar, John Minna, and Paul A. Bunn, Jr.
Clin Cancer Res 2006 12: 7117-7125. [Abstract] [Full Text] [PDF]  

In vivo Loss of Expression of Argininosuccinate Synthetase in Malignant Pleural Mesothelioma Is a Biomarker for Susceptibility to Arginine Depletion

Peter W. Szlosarek, Astero Klabatsa, Arben Pallaska, Michael Sheaff, Paul Smith, Tim Crook, Matthew J. Grimshaw, Jeremy P. Steele, Robin M. Rudd, Frances R. Balkwill, and Dean A. Fennell
Clin Cancer Res 2006 12: 7126-7131. [Abstract] [Full Text] [PDF]  

Monitoring of Singlet Oxygen Is Useful for Predicting the Photodynamic Effects in the Treatment for Experimental Glioma

Junkoh Yamamoto, Seiji Yamamoto, Toru Hirano, Shaoyi Li, Masayo Koide, Eiji Kohno, Mitsuo Okada, Chikanori Inenaga, Tsutomu Tokuyama, Naoki Yokota, Susumu Terakawa, and Hiroki Namba
Clin Cancer Res 2006 12: 7132-7139. [Abstract] [Full Text] [PDF]  

Inhibition of Growth and Metastasis of Human Hepatocellular Carcinoma by Antisense Oligonucleotide Targeting Signal Transducer and Activator of Transcription 3

Wen-Chang Li, Sheng-Long Ye, Rui-Xia Sun, Yin-Kun Liu, Zhao-You Tang, Youngsoo Kim, James G. Karras, and Hong Zhang
Clin Cancer Res 2006 12: 7140-7148. [Abstract] [Full Text] [PDF] Supplementary Data  

ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome

Pawel Surowiak, Verena Materna, Irina Kaplenko, Marek Spaczynski, Barbara Dolinska-Krajewska, Elzbieta Gebarowska, Manfred Dietel, Maciej Zabel, and Hermann Lage
Clin Cancer Res 2006 12: 7149-7158. [Abstract] [Full Text] [PDF] Supplementary Data  

Antiestrogenic Glyceollins Suppress Human Breast and Ovarian Carcinoma Tumorigenesis

Virgilo A. Salvo, Stephen M. Boué, Juan P. Fonseca, Steven Elliott, Cynthia Corbitt, Bridgette M. Collins-Burow, Tyler J. Curiel, Sudesh K. Srivastav, Betty Y. Shih, Carol Carter-Wientjes, Charles E. Wood, Paul W. Erhardt, Barbara S. Beckman, John A. McLachlan, Thomas E. Cleveland, and Matthew E. Burow
Clin Cancer Res 2006 12: 7159-7164. [Abstract] [Full Text] [PDF]  

A Novel Anticancer Effect of Thalidomide: Inhibition of Intercellular Adhesion Molecule-1–Mediated Cell Invasion and Metastasis through Suppression of Nuclear Factor-B

Yi-Chu Lin, Chia-Tung Shun, Ming-Shiang Wu, and Ching-Chow Chen
Clin Cancer Res 2006 12: 7165-7173. [Abstract] [Full Text] [PDF]  

Heterogeneous CD52 Expression among Hematologic Neoplasms: Implications for the Use of Alemtuzumab (CAMPATH-1H)

Scott J. Rodig, Jeremy S. Abramson, Geraldine S. Pinkus, Steven P. Treon, David M. Dorfman, Henry Y. Dong, Margaret A. Shipp, and Jeffery L. Kutok
Clin Cancer Res 2006 12: 7174-7179. [Abstract] [Full Text] [PDF]  

Dasatinib (BMS-354825) Pharmacokinetics and Pharmacodynamic Biomarkers in Animal Models Predict Optimal Clinical Exposure

Feng R. Luo, Zheng Yang, Amy Camuso, Richard Smykla, Kelly McGlinchey, Krista Fager, Christine Flefleh, Stephen Castaneda, Ivan Inigo, David Kan, Mei-Li Wen, Robert Kramer, Anne Blackwood-Chirchir, and Francis Y. Lee
Clin Cancer Res 2006 12: 7180-7186. [Abstract] [Full Text] [PDF]  

Cancer Susceptibility and Prevention:

Second Hand Smoke Exposure and Survival in Early-Stage Non–Small-Cell Lung Cancer Patients

Wei Zhou, Rebecca S. Heist, Geoffrey Liu, Kofi Asomaning, David P. Miller, Donna S. Neuberg, John C. Wain, Thomas J. Lynch, and David C. Christiani
Clin Cancer Res 2006 12: 7187-7193. [Abstract] [Full Text] [PDF]  

Joint Effect of Mutagen Sensitivity and Insulin-Like Growth Factors in Predicting the Risk of Developing Secondary Primary Tumors and Tumor Recurrence in Patients with Head and Neck Cancer

Xifeng Wu, Jian Gu, Qiong Dong, Maosheng Huang, Kim-Anh Do, Waun Ki Hong, and Margaret R. Spitz
Clin Cancer Res 2006 12: 7194-7201. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.