The Biology Behind:

CpG Island Methylator Phenotype and Childhood Leukemia

Norman J. Lacayo, Jorge F. DiMartino, Michael C. Wei, and Gary V. Dahl
Clin Cancer Res 2006 12: 4787 -4789 doi: 10.1158/1078-0432.CCR-06-0651 [Full Text] [PDF]  

Molecular Pathways:

Estrogen Receptor Pathway: Resistance to Endocrine Therapy and New Therapeutic Approaches

Beverly Moy and Paul E. Goss
Clin Cancer Res 2006 12: 4790-4793 doi: 10.1158/1078-0432.CCR-06-1535 [Abstract] [Full Text] [PDF]  

Review:

Improving Antitumor Immune Responses by Circumventing Immunoregulatory Cells and Mechanisms

Gregory Lizée, Laszlo G. Radvanyi, Willem W. Overwijk, and Patrick Hwu
Clin Cancer Res 2006 12: 4794-4803 doi: 10.1158/1078-0432.CCR-06-0944 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Characterization and Expression of CT45 in Hodgkin's Lymphoma

Hans-Jürgen Heidebrecht, Alexander Claviez, Marie Luise Kruse, Marc Pollmann, Friedrich Buck, Sönke Harder, Markus Tiemann, Wolfgang Dörffel, and Reza Parwaresch
Clin Cancer Res 2006 12: 4804-4811 doi: 10.1158/1078-0432.CCR-06-0186 [Abstract] [Full Text] [PDF]  

Th1 Response and Cytotoxicity Genes Are Down-Regulated in Cutaneous T-Cell Lymphoma

Sonja Hahtola, Soile Tuomela, Laura Elo, Tiina Häkkinen, Leena Karenko, Boguslaw Nedoszytko, Hannele Heikkilä, Ulpu Saarialho-Kere, Jadwiga Roszkiewicz, Tero Aittokallio, Riitta Lahesmaa, and Annamari Ranki
Clin Cancer Res 2006 12: 4812-4821 doi: 10.1158/1078-0432.CCR-06-0532 [Abstract] [Full Text] [PDF]  

Natural Killer Receptors on CD8 T Cells and Natural Killer Cells from Different HLA-C Phenotypes in Melanoma Patients

José A. Campillo, Jorge A. Martínez-Escribano, M. Rosa Moya-Quiles, Luis A. Marín, Manuel Muro, Natalia Guerra, Antonio Parrado, Matilde Campos, José F. Frías, Alfredo Minguela, Ana M. García-Alonso, and María Rocío Álvarez-López
Clin Cancer Res 2006 12: 4822-4831 doi: 10.1158/1078-0432.CCR-06-0019 [Abstract] [Full Text] [PDF]  

CHEK2-Positive Breast Cancers in Young Polish Women

Cezary Cybulski, Bohdan Górski, Tomasz Huzarski, Tomasz Byrski, Jacek Gronwald, Tadeusz Debniak, Dominika Wokolorczyk, Anna Jakubowska, Elzbieta Kowalska, Oleg Oszurek, Steven A. Narod, and Jan Lubinski
Clin Cancer Res 2006 12: 4832-4835 doi: 10.1158/1078-0432.CCR-06-0158 [Abstract] [Full Text] [PDF]  

Up-Regulation of Endothelial Delta-like 4 Expression Correlates with Vessel Maturation in Bladder Cancer

Nilay S. Patel, Michael S. Dobbie, Mark Rochester, Graham Steers, Richard Poulsom, Karena Le Monnier, David W. Cranston, Ji-Liang Li, and Adrian L. Harris
Clin Cancer Res 2006 12: 4836-4844 doi: 10.1158/1078-0432.CCR-06-0285 [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

CpG Island Methylator Phenotype Redefines the Prognostic Effect of t(12;21) in Childhood Acute Lymphoblastic Leukemia

Jose Roman-Gomez, Antonio Jimenez-Velasco, Xabier Agirre, Juan A. Castillejo, German Navarro, Maria J. Calasanz, Leire Garate, Edurne San Jose-Eneriz, Lucia Cordeu, Felipe Prosper, Anabel Heiniger, and Antonio Torres
Clin Cancer Res 2006 12: 4845-4850 doi: 10.1158/1078-0432.CCR-05-2592 [Abstract] [Full Text] [PDF]  

Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma

Xiao-Song Wang, Zheng Zhang, Hong-Cheng Wang, Jian-Liang Cai, Qing-Wen Xu, Meng-Qiang Li, Yi-Cheng Chen, Xiao-Ping Qian, Tian-Jing Lu, Li-Zhang Yu, Yu Zhang, Dian-Qi Xin, Yan-Qun Na, and Wei-Feng Chen
Clin Cancer Res 2006 12: 4851-4858 doi: 10.1158/1078-0432.CCR-06-0134 [Abstract] [Full Text] [PDF] Supplementary Data  

Progenitor Marker CD133 mRNA Is Elevated in Peripheral Blood of Cancer Patients with Bone Metastases

Niven Mehra, Maarten Penning, Jolanda Maas, Laurens V. Beerepoot, Nancy van Daal, Carla H. van Gils, Rachel H. Giles, and Emile E. Voest
Clin Cancer Res 2006 12: 4859-4866 doi: 10.1158/1078-0432.CCR-06-0422 [Abstract] [Full Text] [PDF]  

MDM2 Promoter SNP309 Is Associated with the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C

Narayan Dharel, Naoya Kato, Ryosuke Muroyama, Masaru Moriyama, Run-Xuan Shao, Takao Kawabe, and Masao Omata
Clin Cancer Res 2006 12: 4867-4871 doi: 10.1158/1078-0432.CCR-06-0111 [Abstract] [Full Text] [PDF]  

Preoperative Serum Caveolin-1 as a Prognostic Marker for Recurrence in a Radical Prostatectomy Cohort

Salahaldin A. Tahir, Anna Frolov, Teresa G. Hayes, Martha P. Mims, Brian J. Miles, Seth P. Lerner, Thomas M. Wheeler, Gustavo Ayala, Timothy C. Thompson, and Dov Kadmon
Clin Cancer Res 2006 12: 4872-4875 doi: 10.1158/1078-0432.CCR-06-0417 [Abstract] [Full Text] [PDF]  

Presence of Phosphorylated Hepatocyte Growth Factor Receptor/c-Met Is Associated with Tumor Progression and Survival in Patients with Conventional Renal Cell Carcinoma

Yasuyoshi Miyata, Hiroshi Kanetake, and Shigeru Kanda
Clin Cancer Res 2006 12: 4876-4881 doi: 10.1158/1078-0432.CCR-06-0362 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

A Phase 1 Study of ABT-751, an Orally Bioavailable Tubulin Inhibitor, Administered Daily for 7 Days Every 21 Days in Pediatric Patients with Solid Tumors

Elizabeth Fox, John M. Maris, Brigitte C. Widemann, Kysa Meek, Anne Goodwin, Wendy Goodspeed, Marie Kromplewski, Molly E. Fouts, Diane Medina, Steve Y. Cho, Susan L. Cohn, Andrew Krivoshik, Anne E. Hagey, Peter C. Adamson, and Frank M. Balis
Clin Cancer Res 2006 12: 4882-4887 doi: 10.1158/1078-0432.CCR-06-0534 [Abstract] [Full Text] [PDF]  

Real-time Dose Adjustment of Cyclophosphamide in a Preparative Regimen for Hematopoietic Cell Transplant: A Bayesian Pharmacokinetic Approach

David H. Salinger, Jeannine S. McCune, Aaron G. Ren, Danny D. Shen, John T. Slattery, Brian Phillips, George B. McDonald, and Paolo Vicini
Clin Cancer Res 2006 12: 4888-4898 doi: 10.1158/1078-0432.CCR-05-2079 [Abstract] [Full Text] [PDF]  

Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08

Patrick Y. Wen, W.K. Alfred Yung, Kathleen R. Lamborn, Patricia L. Dahia, Yanfeng Wang, Bin Peng, Lauren E. Abrey, Jeffrey Raizer, Timothy F. Cloughesy, Karen Fink, Mark Gilbert, Susan Chang, Larry Junck, David Schiff, Frank Lieberman, Howard A. Fine, Minesh Mehta, H. Ian Robins, Lisa M. DeAngelis, Morris D. Groves, Vinay K. Puduvalli, Victor Levin, Charles Conrad, Elizabeth A. Maher, Kenneth Aldape, Michael Hayes, Laurie Letvak, Merrill J. Egorin, Renaud Capdeville, Richard Kaplan, Anthony J. Murgo, Charles Stiles, and Michael D. Prados
Clin Cancer Res 2006 12: 4899-4907 doi: 10.1158/1078-0432.CCR-06-0773 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice

Xiaohua Xin, Tinya J. Abrams, Paul W. Hollenbach, Katherine G. Rendahl, Yan Tang, Yoko A. Oei, Millicent G. Embry, Debbie E. Swinarski, Evelyn N. Garrett, Nancy K. Pryer, Suzanne Trudel, Bahija Jallal, Dirk B. Mendel, and Carla C. Heise
Clin Cancer Res 2006 12: 4908-4915 doi: 10.1158/1078-0432.CCR-06-0957 [Abstract] [Full Text] [PDF]  

Focal Adhesion Kinase Targeting Using In vivo Short Interfering RNA Delivery in Neutral Liposomes for Ovarian Carcinoma Therapy

Jyotsnabaran Halder, Aparna A. Kamat, Charles N. Landen, Jr., Liz Y. Han, Susan K. Lutgendorf, Yvonne G. Lin, William M. Merritt, Nicholas B. Jennings, Arturo Chavez-Reyes, Robert L. Coleman, David M. Gershenson, Rosemarie Schmandt, Steven W. Cole, Gabriel Lopez-Berestein, and Anil K. Sood
Clin Cancer Res 2006 12: 4916-4924 doi: 10.1158/1078-0432.CCR-06-0021 [Abstract] [Full Text] [PDF]  

Antitumor Effect of Trastuzumab for Pancreatic Cancer with High HER-2 Expression and Enhancement of Effect by Combined Therapy with Gemcitabine

Kenjiro Kimura, Tetsuji Sawada, Midori Komatsu, Masafumi Inoue, Kazuya Muguruma, Tamahiro Nishihara, Yoshito Yamashita, Nobuya Yamada, Masaichi Ohira, and Kosei Hirakawa
Clin Cancer Res 2006 12: 4925-4932 doi: 10.1158/1078-0432.CCR-06-0544 [Abstract] [Full Text] [PDF]  

Delivery of Telomerase Reverse Transcriptase Small Interfering RNA in Complex with Positively Charged Single-Walled Carbon Nanotubes Suppresses Tumor Growth

Zhuohan Zhang, Xiaoying Yang, Yuan Zhang, Bin Zeng, Shujing Wang, Tianhui Zhu, Richard B.S. Roden, Yongsheng Chen, and Rongcun Yang
Clin Cancer Res 2006 12: 4933-4939 doi: 10.1158/1078-0432.CCR-05-2831 [Abstract] [Full Text] [PDF] Supplementary Data  

Bcl-2 Protein in 518A2 Melanoma Cells In vivo and In vitro

Luba Benimetskaya, Kanyalakshmi Ayyanar, Noah Kornblum, Daniela Castanotto, John Rossi, Sijian Wu, Johnathan Lai, Bob D. Brown, Natalia Popova, Paul Miller, Harilyn McMicken, Yin Chen, and C.A. Stein
Clin Cancer Res 2006 12: 4940-4948 doi: 10.1158/1078-0432.CCR-06-1002 [Abstract] [Full Text] [PDF]  

Peptidome from Renal Cell Carcinoma Contains Antigens Recognized by CD4⁺ T Cells and Shared among Tumors of Different Histology

Elena Tassi, Valeria Facchinetti, Samantha Seresini, Anna Borri, Giacomo Dell'Antonio, Claudio Garavaglia, Giulia Casorati, and Maria Pia Protti
Clin Cancer Res 2006 12: 4949-4957 doi: 10.1158/1078-0432.CCR-06-0995 [Abstract] [Full Text] [PDF]  

Successful Radiotherapy of Tumor in Pretargeted Mice by ¹⁸⁸Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue

Guozheng Liu, Shuping Dou, George Mardirossian, Jiang He, Surong Zhang, Xinrong Liu, Mary Rusckowski, and Donald J. Hnatowich
Clin Cancer Res 2006 12: 4958-4964 doi: 10.1158/1078-0432.CCR-06-0844 [Abstract] [Full Text] [PDF]  

In vitro and In vivo Evidence of Metallopanstimulin-1 in Gastric Cancer Progression and Tumorigenicity

Yun-wei Wang, Ying Qu, Jian-fang Li, Xue-hua Chen, Bing-ya Liu, Qin-long Gu, and Zheng-gang Zhu
Clin Cancer Res 2006 12: 4965-4973 doi: 10.1158/1078-0432.CCR-05-2316 [Abstract] [Full Text] [PDF]  

Copper Binding by Tetrathiomolybdate Attenuates Angiogenesis and Tumor Cell Proliferation through the Inhibition of Superoxide Dismutase 1

Jose C. Juarez, Oscar Betancourt, Jr., Steven R. Pirie-Shepherd, Xiaojun Guan, Melissa L. Price, David E. Shaw, Andrew P. Mazar, and Fernando Doñate
Clin Cancer Res 2006 12: 4974-4982 doi: 10.1158/1078-0432.CCR-06-0171 [Abstract] [Full Text] [PDF]  

Tumor-Directed Radiation and the Immunotoxin SS1P in the Treatment of Mesothelin-Expressing Tumor Xenografts

Raffit Hassan, Juanita Williams-Gould, Seth M. Steinberg, David J. Liewehr, Junko Yokokawa, Kwong Y. Tsang, Robert J. Surawski, Tamalee Scott, and Kevin Camphausen
Clin Cancer Res 2006 12: 4983-4988 doi: 10.1158/1078-0432.CCR-06-0441 [Abstract] [Full Text] [PDF]  

Radiosensitivity Enhancement by Combined Treatment of Celecoxib and Gefitinib on Human Lung Cancer Cells

Ji Sun Park, Hyun Jung Jun, Moon Jun Cho, Kwan Ho Cho, Jin Soo Lee, Jae Ill Zo, and Hongryull Pyo
Clin Cancer Res 2006 12: 4989-4999 doi: 10.1158/1078-0432.CCR-05-2259 [Abstract] [Full Text] [PDF] Supplementary Data  

Letters to the Editor:

Cancer Chemotherapy and Cognitive Function in Rodent Models: Memory Impairment Induced by Cyclophosphamide in Mice

André B. Reiriz, Gustavo K. Reolon, Thales Preissler, Joemerson O. Rosado, João Antônio P. Henriques, Rafael Roesler, Gilberto Schwartsmann, Garrick D. Lee, Dan L. Longo, and Donald K. Ingram
Clin Cancer Res 2006 12: 5000-5001 doi: 10.1158/1078-0432.CCR-06-0138 [Full Text] [PDF]  

Corrections:

Article on Reduced Plasma RNA Integrity

Clin Cancer Res 2006 12: 5002 doi: 10.1158/1078-0432.CCR-12-16-COR1 [Full Text] [PDF]  

Article on BCL-2 as a Prognostic Marker

Clin Cancer Res 2006 12: 5002 doi: 10.1158/1078-0432.CCR-12-16-COR2 [Full Text] [PDF]  

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