Editorials:

Challenges of Evaluating the Cardiac Effects of Anticancer Agents

Susan E. Bates, Douglas R. Rosing, Tito Fojo, and Richard L. Piekarz
Clin Cancer Res 2006 12: 3871-3874. [Full Text] [PDF]  

A Blood-Based Test for Epidermal Growth Factor Receptor Mutations in Lung Cancer

Daphne W. Bell and Daniel A. Haber
Clin Cancer Res 2006 12: 3875-3877. [Full Text] [PDF]  

The Biology Behind:

Emerging Biology of Malignant Salivary Gland Tumors Offers New Insights into the Classification and Treatment of Mucoepidermoid Cancer

Frederic J. Kaye
Clin Cancer Res 2006 12: 3878-3881. [Full Text] [PDF]  

Molecular Pathways:

Metastasis Suppressor Proteins: Discovery, Molecular Mechanisms, and Clinical Application

Carrie W. Rinker-Schaeffer, James P. O'Keefe, Danny R. Welch, and Dan Theodorescu
Clin Cancer Res 2006 12: 3882-3889. [Full Text] [PDF]  

Review:

Immune Escape Associated with Functional Defects in Antigen-Processing Machinery in Head and Neck Cancer

Robert L. Ferris, Theresa L. Whiteside, and Soldano Ferrone
Clin Cancer Res 2006 12: 3890-3895. [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Accurate Prediction of BRCA1 and BRCA2 Heterozygous Genotype Using Expression Profiling after Induced DNA Damage

Zsofia Kote-Jarai, Lucy Matthews, Ana Osorio, Susan Shanley, Ian Giddings, Francois Moreews, Imogen Locke, D. Gareth Evans, Diana Eccles, The Carrier Clinic Collaborators, Richard D. Williams, Mark Girolami, Colin Campbell, and Ros Eeles
Clin Cancer Res 2006 12: 3896-3901. [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

MECT1-MAML2 Fusion Transcript Defines a Favorable Subset of Mucoepidermoid Carcinoma

Mitsukuni Okabe, Satoru Miyabe, Hitoshi Nagatsuka, Akihiro Terada, Nobuhiro Hanai, Motoo Yokoi, Kazuo Shimozato, Tadaaki Eimoto, Shigeo Nakamura, Noriyuki Nagai, Yasuhisa Hasegawa, and Hiroshi Inagaki
Clin Cancer Res 2006 12: 3902-3907. [Abstract] [Full Text] [PDF]  

Exon 19 Deletion Mutations of Epidermal Growth Factor Receptor Are Associated with Prolonged Survival in Non–Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib

David M. Jackman, Beow Y. Yeap, Lecia V. Sequist, Neal Lindeman, Alison J. Holmes, Victoria A. Joshi, Daphne W. Bell, Mark S. Huberman, Balazs Halmos, Michael S. Rabin, Daniel A. Haber, Thomas J. Lynch, Matthew Meyerson, Bruce E. Johnson, and Pasi A. Jänne
Clin Cancer Res 2006 12: 3908-3914. [Abstract] [Full Text] [PDF]  

Detection of Epidermal Growth Factor Receptor Mutations in Serum as a Predictor of the Response to Gefitinib in Patients with Non–Small-Cell Lung Cancer

Hideharu Kimura, Kazuo Kasahara, Makoto Kawaishi, Hideo Kunitoh, Tomohide Tamura, Brian Holloway, and Kazuto Nishio
Clin Cancer Res 2006 12: 3915-3921. [Abstract] [Full Text] [PDF]  

Expression of Np73 and TAp73 Independently Associated with Radiosensitivities and Prognoses in Cervical Squamous Cell Carcinoma

Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Annie Nga-Yin Cheung, Xiao-Yun Liao, Tsin-Wah Leung, and Hextan Yuen-Sheung Ngan
Clin Cancer Res 2006 12: 3922-3927. [Abstract] [Full Text] [PDF]  

Orotate Phosphoribosyltransferase Gene Polymorphism Predicts Toxicity in Patients Treated with Bolus 5-Fluorouracil Regimen

Wataru Ichikawa, Takehiro Takahashi, Kenichi Suto, Yasutsuna Sasaki, and Renzo Hirayama
Clin Cancer Res 2006 12: 3928-3934. [Abstract] [Full Text] [PDF]  

Prognostic Associations of Activated Mitogen-Activated Protein Kinase and Akt Pathways in Glioblastoma

Christopher E. Pelloski, E Lin, Li Zhang, W.K. Alfred Yung, Howard Colman, Juinn-Lin Liu, Shaio Y. Woo, Amy B. Heimberger, Dima Suki, Michael Prados, Susan Chang, Fredrick G. Barker, III, Gregory N. Fuller, and Kenneth D. Aldape
Clin Cancer Res 2006 12: 3935-3941. [Abstract] [Full Text] [PDF]  

Positron Emission Tomography Using [¹⁸F]Galacto-RGD Identifies the Level of Integrin _vß₃ Expression in Man

Ambros J. Beer, Roland Haubner, Mario Sarbia, Michael Goebel, Stephan Luderschmidt, Anca Ligia Grosu, Oliver Schnell, Markus Niemeyer, Horst Kessler, Hans-Jürgen Wester, Wolfgang A. Weber, and Markus Schwaiger
Clin Cancer Res 2006 12: 3942-3949. [Abstract] [Full Text] [PDF]  

Molecular Profiling of Laser-Microdissected Matched Tumor and Normal Breast Tissue Identifies Karyopherin 2 as a Potential Novel Prognostic Marker in Breast Cancer

Edgar Dahl, Glen Kristiansen, Kathrin Gottlob, Irina Klaman, Elke Ebner, Bernd Hinzmann, Klaus Hermann, Christian Pilarsky, Matthias Dürst, Monika Klinkhammer-Schalke, Hagen Blaszyk, Ruth Knuechel, Arndt Hartmann, André Rosenthal, and Peter J. Wild
Clin Cancer Res 2006 12: 3950-3960. [Abstract] [Full Text] [PDF]  

8q Gain Is an Independent Predictor of Poor Survival in Diagnostic Needle Biopsies from Prostate Cancer Suspects

Franclim R. Ribeiro, Carmen Jerónimo, Rui Henrique, Daniel Fonseca, Jorge Oliveira, Ragnhild A. Lothe, and Manuel R. Teixeira
Clin Cancer Res 2006 12: 3961-3970. [Abstract] [Full Text] [PDF]  

Clinical Significance of Aminopeptidase N in Non–Small Cell Lung Cancer

Takahiro Tokuhara, Noboru Hattori, Hisao Ishida, Tatsuya Hirai, Masahiko Higashiyama, Ken Kodama, and Masayuki Miyake
Clin Cancer Res 2006 12: 3971-3978. [Abstract] [Full Text] [PDF]  

Concomitant Analysis of Salivary Tumor Markers—A New Diagnostic Tool for Oral Cancer

Rafael Nagler, Gideon Bahar, Thomas Shpitzer, and Raphael Feinmesser
Clin Cancer Res 2006 12: 3979-3984. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

A Distinct p53 Protein Isoform Signature Reflects the Onset of Induction Chemotherapy for Acute Myeloid Leukemia

Nina Anensen, Anne Margrete Oyan, Jean-Christophe Bourdon, Karl Henning Kalland, Oystein Bruserud, and Bjorn Tore Gjertsen
Clin Cancer Res 2006 12: 3985-3992. [Abstract] [Full Text] [PDF]  

A Phase I Study of Ultra Low Dose Interleukin-2 and Stem Cell Factor in Patients with HIV Infection or HIV and Cancer

Manisha H. Shah, Aharon G. Freud, Don M. Benson, Jr., Amy K. Ferkitich, Bruce J. Dezube, Zale P. Bernstein, and Michael A. Caligiuri
Clin Cancer Res 2006 12: 3993-3996. [Abstract] [Full Text] [PDF]  

Cardiotoxicity of Histone Deacetylase Inhibitor Depsipeptide in Patients with Metastatic Neuroendocrine Tumors

Manisha H. Shah, Philip Binkley, Kenneth Chan, Jim Xiao, Daria Arbogast, Minden Collamore, Yasser Farra, Donn Young, and Michael Grever
Clin Cancer Res 2006 12: 3997-4003. [Abstract] [Full Text] [PDF]  

Phase I Trial of Doxorubicin-Containing Low Temperature Sensitive Liposomes in Spontaneous Canine Tumors

Marlene L. Hauck, Susan M. LaRue, William P. Petros, Jean M. Poulson, Daohai Yu, Ivan Spasojevic, Amy F. Pruitt, Allison Klein, Beth Case, Donald E. Thrall, David Needham, and Mark W. Dewhirst
Clin Cancer Res 2006 12: 4004-4010. [Abstract] [Full Text] [PDF]  

Clinical and Pharmacokinetic Study of Clofarabine in Chronic Lymphocytic Leukemia: Strategy for Treatment

Varsha Gandhi, William Plunkett, Peter L. Bonate, Min Du, Billie Nowak, Susan Lerner, and Michael J. Keating
Clin Cancer Res 2006 12: 4011-4017. [Abstract] [Full Text] [PDF]  

Phase II Study of Pomegranate Juice for Men with Rising Prostate-Specific Antigen following Surgery or Radiation for Prostate Cancer

Allan J. Pantuck, John T. Leppert, Nazy Zomorodian, William Aronson, Jenny Hong, R. James Barnard, Navindra Seeram, Harley Liker, Hejing Wang, Robert Elashoff, David Heber, Michael Aviram, Louis Ignarro, and Arie Belldegrun
Clin Cancer Res 2006 12: 4018-4026. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Complement-Induced Cell Death by Rituximab Depends on CD20 Expression Level and Acts Complementary to Antibody-Dependent Cellular Cytotoxicity

Tom van Meerten, Rozemarijn S. van Rijn, Samantha Hol, Anton Hagenbeek, and Saskia B. Ebeling
Clin Cancer Res 2006 12: 4027-4035. [Abstract] [Full Text] [PDF]  

Humanization of the Bispecific Epidermal Growth Factor Receptor x CD3 Diabody and Its Efficacy as a Potential Clinical Reagent

Ryutaro Asano, Yukiko Sone, Koki Makabe, Kouhei Tsumoto, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Toshio Kudo, and Izumi Kumagai
Clin Cancer Res 2006 12: 4036-4042. [Abstract] [Full Text] [PDF]  

Establishment in Severe Combined Immunodeficiency Mice of Subrenal Capsule Xenografts and Transplantable Tumor Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumor Progression–Related Changes

Jean-Claude Cutz, Jun Guan, Jane Bayani, Maisa Yoshimoto, Hui Xue, Margaret Sutcliffe, John English, Julia Flint, Jean LeRiche, John Yee, Jeremy A. Squire, Peter W. Gout, Stephen Lam, and Yu-Zhuo Wang
Clin Cancer Res 2006 12: 4043-4054. [Abstract] [Full Text] [PDF]  

Ex vivo and In vivo Delivery of Anti-Tissue Factor Short Interfering RNA Inhibits Mouse Pulmonary Metastasis of B16 Melanoma Cells

Mohammed Amarzguioui, Qian Peng, Merete T. Wiiger, Vlada Vasovic, Eshrat Babaie, Torgeir Holen, Jahn M. Nesland, and Hans Prydz
Clin Cancer Res 2006 12: 4055-4061. [Abstract] [Full Text] [PDF]  

Natural and Synthetic Progestins Accelerate 7,12-Dimethylbenz[a]Anthracene-Initiated Mammary Tumors and Increase Angiogenesis in Sprague-Dawley Rats

Indira Benakanakere, Cynthia Besch-Williford, Jennifer Schnell, Sandra Brandt, Mark R. Ellersieck, Alfredo Molinolo, and Salman M. Hyder
Clin Cancer Res 2006 12: 4062-4071. [Abstract] [Full Text] [PDF]  

Pharmacologic Basis for the Enhanced Efficacy of Dutasteride against Prostatic Cancers

Yi Xu, Susan L. Dalrymple, Robyn E. Becker, Samuel R. Denmeade, and John T. Isaacs
Clin Cancer Res 2006 12: 4072-4079. [Abstract] [Full Text] [PDF]  

PHA-680632, a Novel Aurora Kinase Inhibitor with Potent Antitumoral Activity

Chiara Soncini, Patrizia Carpinelli, Laura Gianellini, Daniele Fancelli, Paola Vianello, Luisa Rusconi, Paola Storici, Paola Zugnoni, Enrico Pesenti, Valter Croci, Roberta Ceruti, Maria Laura Giorgini, Paolo Cappella, Dario Ballinari, Francesco Sola, Mario Varasi, Rodrigo Bravo, and Jürgen Moll
Clin Cancer Res 2006 12: 4080-4089. [Abstract] [Full Text] [PDF]  

Effect of the Second-Generation Vascular Disrupting Agent OXi4503 on Tumor Vascularity

Howard W. Salmon and Dietmar W. Siemann
Clin Cancer Res 2006 12: 4090-4094. [Abstract] [Full Text] [PDF]  

Captopril, an Angiotensin-Converting Enzyme Inhibitor, Promotes Growth of Immunogenic Tumors in Mice

Piotr J. Wysocki, Eliza P. Kwiatkowska, Urszula Kazimierczak, Wiktoria Suchorska, Dariusz W. Kowalczyk, and Andrzej Mackiewicz
Clin Cancer Res 2006 12: 4095-4102. [Abstract] [Full Text] [PDF]  

Signaling via ErbB2 and ErbB3 Associates with Resistance and Epidermal Growth Factor Receptor (EGFR) Amplification with Sensitivity to EGFR Inhibitor Gefitinib in Head and Neck Squamous Cell Carcinoma Cells

Kaisa Erjala, Maria Sundvall, Teemu T. Junttila, Na Zhang, Mika Savisalo, Pekka Mali, Jarmo Kulmala, Jaakko Pulkkinen, Reidar Grenman, and Klaus Elenius
Clin Cancer Res 2006 12: 4103-4111. [Abstract] [Full Text] [PDF]  

Calcitonin Gene-Related Peptide and Substance P Regulate the Intestinal Radiation Response

Junru Wang, Xiaohua Qiu, Ashwini Kulkarni, and Martin Hauer-Jensen
Clin Cancer Res 2006 12: 4112-4118. [Abstract] [Full Text] [PDF]  

Blockage of Epidermal Growth Factor Receptor-Phosphatidylinositol 3-Kinase-AKT Signaling Increases Radiosensitivity of K-RAS Mutated Human Tumor Cells In vitro by Affecting DNA Repair

Mahmoud Toulany, Ulla Kasten-Pisula, Ingo Brammer, Shaomeng Wang, Jianyong Chen, Klaus Dittmann, Michael Baumann, Ekkehard Dikomey, and H. Peter Rodemann
Clin Cancer Res 2006 12: 4119-4126. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

ABCB1 2677G>T/A Genotype and Paclitaxel Pharmacogenetics in Ovarian Cancer

Sharon Marsh, Cristi R. King, Howard L. McLeod, Jim Paul, Gillian Gifford, Robert Brown, Henrik Gréen, Curt Peterson, Peter Söderkvist, Per Rosenberg, and György Horvath
Clin Cancer Res 2006 12: 4127-4129. [Full Text] [PDF]  

Corrections:

Article on Sex-Specific Survival Advantage with Parathyroid Hormone—Related Protein

Clin Cancer Res 2006 12: 4130. [Full Text] [PDF]  

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