Editor's Note:

Progress in Chemoprevention: AACR Task Force Report

Paul F. Engstrom
Clin Cancer Res 2006 12: 3645. [Full Text] [PDF]  

Editorials:

Cardiac Safety, Risk Management, and Oncology Drug Development

Howard J. Fingert and Mary L. Varterasian
Clin Cancer Res 2006 12: 3646-3647. [Full Text] [PDF]  

The Biology Behind:

FLIPping the Balance between Apoptosis and Proliferation in Thyroid Cancer

Robin Mathew and Eileen White
Clin Cancer Res 2006 12: 3648-3651. [Full Text] [PDF]  

CCR Practice of Translational Oncology:

Biological Markers for Non–Small Cell Lung Cancer Patient Selection for Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy

Paul A. Bunn, Jr., Rafal Dziadziuszko, Marileila Varella-Garcia, Wilbur A. Franklin, Samir E. Witta, Karen Kelly, and Fred R. Hirsch
Clin Cancer Res 2006 12: 3652-3656. [Full Text] [PDF]  

Molecular Pathways:

Targeting the c-Met Signaling Pathway in Cancer

Benedetta Peruzzi and Donald P. Bottaro
Clin Cancer Res 2006 12: 3657-3660. [Abstract] [Full Text] [PDF]  

AACR Task Force Report:

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

Gary J. Kelloff, Scott M. Lippman, Andrew J. Dannenberg, Caroline C. Sigman, Homer L. Pearce, Brian J. Reid, Eva Szabo, V. Craig Jordan, Margaret R. Spitz, Gordon B. Mills, Vali A. Papadimitrakopoulou, Reuben Lotan, Bharat B. Aggarwal, Robert S. Bresalier, Jeri Kim, Banu Arun, Karen H. Lu, Melanie E. Thomas, Helen E. Rhodes, Molly A. Brewer, Michele Follen, Dong M. Shin, Howard L. Parnes, Jill M. Siegfried, Alison A. Evans, William J. Blot, Wong-Ho Chow, Patricia L. Blount, Carlo C. Maley, Kenneth K. Wang, Stephen Lam, J. Jack Lee, Steven M. Dubinett, Paul F. Engstrom, Frank L. Meyskens, Jr., Joyce O'Shaughnessy, Ernest T. Hawk, Bernard Levin, William G. Nelson, Waun Ki Hong for the AACR Task Force on Cancer Prevention
Clin Cancer Res 2006 12: 3661-3697. [Abstract] [Full Text] [PDF]  

Review:

Current Concepts in Bronchioloalveolar Carcinoma Biology

Dan J. Raz, Biao He, Rafael Rosell, and David M. Jablons
Clin Cancer Res 2006 12: 3698-3704. [Full Text] [PDF]  

Human Cancer Biology:

Fas Signaling in Thyroid Carcinomas Is Diverted from Apoptosis to Proliferation

Constantine S. Mitsiades, Vassiliki Poulaki, Galinos Fanourakis, Elias Sozopoulos, Douglas McMillin, Zhaoqin Wen, Gerassimos Voutsinas, Sophia Tseleni-Balafouta, and Nicholas Mitsiades
Clin Cancer Res 2006 12: 3705-3712. [Abstract] [Full Text] [PDF]  

Genetic and Epigenetic Analysis of the Putative Tumor Suppressor km23 in Primary Ovarian, Breast, and Colorectal Cancers

Ian G. Campbell, Wayne A. Phillips, and David Y.H. Choong
Clin Cancer Res 2006 12: 3713-3715. [Abstract] [Full Text] [PDF]  

Aberrant Expression of Collagen Triple Helix Repeat Containing 1 in Human Solid Cancers

Liren Tang, Derek L. Dai, Mingwan Su, Magdalena Martinka, Gang Li, and Youwen Zhou
Clin Cancer Res 2006 12: 3716-3722. [Abstract] [Full Text] [PDF]  

Human In vivo Dose-Response to Controlled, Low-Dose Low Linear Energy Transfer Ionizing Radiation Exposure

Zelanna Goldberg, David M. Rocke, Chad Schwietert, Susanne R. Berglund, Alison Santana, Angela Jones, Jörg Lehmann, Robin Stern, Ruixiao Lu, and Christine Hartmann Siantar
Clin Cancer Res 2006 12: 3723-3729. [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Roles of KLF6 and KLF6-SV1 in Ovarian Cancer Progression and Intraperitoneal Dissemination

Analisa DiFeo, Goutham Narla, Jennifer Hirshfeld, Olga Camacho-Vanegas, Jyothsna Narla, Stephen L. Rose, Tamara Kalir, Shen Yao, Alice Levine, Michael J. Birrer, Tomas Bonome, Scott L. Friedman, Richard E. Buller, and John A. Martignetti
Clin Cancer Res 2006 12: 3730-3739. [Abstract] [Full Text] [PDF]  

Expression of p53R2 Is Related to Prognosis in Patients with Esophageal Squamous Cell Carcinoma

Hiroshi Okumura, Shoji Natsugoe, Naoya Yokomakura, Yoshiaki Kita, Masataka Matsumoto, Yasuto Uchikado, Tetsuro Setoyama, Tetsuhiro Owaki, Sumiya Ishigami, and Takashi Aikou
Clin Cancer Res 2006 12: 3740-3745. [Abstract] [Full Text] [PDF]  

Application of Intraoperative Ultrasound to Nonsentinel Node Assessment in Primary Breast Cancer

Giu-Cheng Hsu, Chih-Hung Ku, Jyh-Cherng Yu, Chung-Bo Hsieh, Cheng-Pin Yu, and Tsu-Yi Chao
Clin Cancer Res 2006 12: 3746-3753. [Abstract] [Full Text] [PDF]  

Lack of Methylthioadenosine Phosphorylase Expression in Mantle Cell Lymphoma Is Associated with Shorter Survival: Implications for a Potential Targeted Therapy

Silvia Marcé, Olga Balagué, Luis Colomo, Antonio Martinez, Sylvia Höller, Neus Villamor, Francesc Bosch, German Ott, Andreas Rosenwald, Lorenzo Leoni, Manel Esteller, Mario F. Fraga, Emili Montserrat, Dolors Colomer, and Elias Campo
Clin Cancer Res 2006 12: 3754-3761. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Cardiac Studies in Patients Treated with Depsipeptide, FK228, in a Phase II Trial for T-Cell Lymphoma

Richard L. Piekarz, A. Robin Frye, John J. Wright, Seth M. Steinberg, David J. Liewehr, Douglas R. Rosing, Vandana Sachdev, Tito Fojo, and Susan E. Bates
Clin Cancer Res 2006 12: 3762-3773. [Abstract] [Full Text] [PDF]  

Dose-Finding Phase I Clinical and Pharmacokinetic Study of Orally Administered Irinotecan in Patients with Advanced Solid Tumors

Isa E.L.M. Kuppens, Eric Dansin, Henk Boot, Celine Feger, Sylvia Assadourian, Maria-Edith Bonneterre, Jos H. Beijnen, Jan H.M. Schellens, and Jacques Bonneterre
Clin Cancer Res 2006 12: 3774-3781. [Abstract] [Full Text] [PDF]  

Phase 1 and Pharmacokinetic Study of Intravenous Irinotecan in Refractory Solid Tumor Patients with Hepatic Dysfunction

Larry J. Schaaf, Lisa A. Hammond, Stuart J. Tipping, Richard M. Goldberg, Rakesh Goel, John G. Kuhn, Langdon L. Miller, Linda D. Compton, Laura A. Cisar, Gary L. Elfring, Gabriela Gruia, J. Patrick McGovren, Nicoletta Pirotta, Donghua Yin, Amarnath Sharma, Barbara A. Duncan, and Mace L. Rothenberg
Clin Cancer Res 2006 12: 3782-3791. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Molecular Targeting and Treatment of EGFRvIII-Positive Gliomas Using Boronated Monoclonal Antibody L8A4

Weilian Yang, Rolf F. Barth, Gong Wu, Shinji Kawabata, Thomas J. Sferra, Achintya K. Bandyopadhyaya, Werner Tjarks, Amy K. Ferketich, Melvin L. Moeschberger, Peter J. Binns, Kent J. Riley, Jeffrey A. Coderre, Michael J. Ciesielski, Robert A. Fenstermaker, and Carol J. Wikstrand
Clin Cancer Res 2006 12: 3792-3802. [Abstract] [Full Text] [PDF]  

Carcinoembryonic Antigen–Targeted Selective Gene Therapy for Gastric Cancer through FZ33 Fiber-Modified Adenovirus Vectors

Toshihiro Tanaka, Jianhua Huang, Sachie Hirai, Motomu Kuroki, Masahide Kuroki, Naoki Watanabe, Kei Tomihara, Kazunori Kato, and Hirofumi Hamada
Clin Cancer Res 2006 12: 3803-3813. [Abstract] [Full Text] [PDF]  

In vitro Peptide Immunization of Target Tax Protein Human T-Cell Leukemia Virus Type 1–Specific CD4⁺ Helper T Lymphocytes

Hiroya Kobayashi, Toshihiro Ngato, Keisuke Sato, Naoko Aoki, Shoji Kimura, Yuetsu Tanaka, Hitoshi Aizawa, Masatoshi Tateno, and Esteban Celis
Clin Cancer Res 2006 12: 3814-3822. [Abstract] [Full Text] [PDF]  

Distinct Effects of Ionizing Radiation on In vivo Murine Kidney and Brain Normal Tissue Gene Expression

Weiling Zhao, Eric Y. Chuang, Mark Mishra, Rania Awwad, Kheem Bisht, Lunching Sun, Phuongmai Nguyen, J. Daniel Pennington, Tony Jau Cheng Wang, C. Matthew Bradbury, Lei Huang, Zhijun Chen, Gil Bar-Sela, Michael E.C. Robbins, and David Gius
Clin Cancer Res 2006 12: 3823-3830. [Abstract] [Full Text] [PDF]  

R-253 Disrupts Microtubule Networks in Multiple Tumor Cell Lines

Tarikere L. Gururaja, Dane Goff, Taisei Kinoshita, Eileen Goldstein, Stephanie Yung, John McLaughlin, Erlina Pali, Jianing Huang, Rajinder Singh, Sarkiz Daniel-Issakani, Yasumichi Hitoshi, R.D.G. Cooper, and Donald G. Payan
Clin Cancer Res 2006 12: 3831-3842. [Abstract] [Full Text] [PDF]  

Local Targeting of Malignant Gliomas by the Diffusible Peptidic Vector 1,4,7,10-Tetraazacyclododecane-1-Glutaric Acid-4,7,10-Triacetic Acid-Substance P

Stefan Kneifel, Dominik Cordier, Stephan Good, Mihai C.S. Ionescu, Anthony Ghaffari, Silvia Hofer, Martin Kretzschmar, Markus Tolnay, Christos Apostolidis, Beatrice Waser, Marlene Arnold, Jan Mueller-Brand, Helmut R. Maecke, Jean Claude Reubi, and Adrian Merlo
Clin Cancer Res 2006 12: 3843-3850. [Abstract] [Full Text] [PDF]  

PIK3CA Mutations in Intraductal Papillary Mucinous Neoplasm/Carcinoma of the Pancreas

Frank Schönleben, Wanglong Qiu, Nancy T. Ciau, Daniel J. Ho, Xiaojun Li, John D. Allendorf, Helen E. Remotti, and Gloria H. Su
Clin Cancer Res 2006 12: 3851-3855. [Abstract] [Full Text] [PDF]  

Expression of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Receptors 1 and 2 in Melanoma

Mary M. McCarthy, Kyle A. DiVito, Mario Sznol, Daniela Kovacs, Ruth Halaban, Aaron J. Berger, Keith T. Flaherty, Robert L. Camp, Rossitza Lazova, David L. Rimm, and Harriet M. Kluger
Clin Cancer Res 2006 12: 3856-3863. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Methylation of the DPYD Promoter and Dihydropyrimidine Dehydrogenase Deficiency

Jinsheng Yu, Howard L. McLeod, Hany H. Ezzeldin, and Robert B. Diasio
Clin Cancer Res 2006 12: 3864. [Full Text] [PDF]  

Low Frequency of BRAF Mutations in Endometrial and in Cervical Carcinomas

Gema Moreno-Bueno, Carolina Sanchez-Estevez, José Palacios, David Hardisson, and Tanri Shiozawa
Clin Cancer Res 2006 12: 3865-3866. [Full Text] [PDF]  

Adjuvant Chemotherapy in Colorectal Cancer Patients with Microsatellite Instability

Toshiaki Watanabe, Takamitsu Kanazawa, Yoshihiro Kazama, Junichiro Tanaka, Toshiaki Tanaka, Soichiro Ishihara, Hirokazu Nagawa, Piero Benatti, Maurizio Ponz de Leon, Roberta Gafá, Giovanni Lanza, Daniela Barana, and Cristina Oliani
Clin Cancer Res 2006 12: 3866-3867. [Full Text] [PDF]  

Corrections:

Article on Microsatellite Instability and Colorectal Cancer Prognosis

Clin Cancer Res 2006 12: 3868-3869. [Full Text] [PDF]  

Article on Cremophor-Free,Albumin-Bound Paclitaxel

Clin Cancer Res 2006 12: 3869. [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.