Editorials:

Irrational Exuberance in Clinical Proteomics

Simon M. Lin and Warren Alden Kibbe
Clin Cancer Res 2005 11: 7963-7964. [Full Text] [PDF]  

The Biology Behind:

Phosphatidylinositol 3-Kinase Inhibitors Are a Triple Threat to Ovarian Cancer

Ramon Parsons
Clin Cancer Res 2005 11: 7965-7966. [Full Text] [PDF]  

Review:

The Progress and Promise of Molecular Imaging Probes in Oncologic Drug Development

Gary J. Kelloff, Kenneth A. Krohn, Steven M. Larson, Ralph Weissleder, David A. Mankoff, John M. Hoffman, Jeanne M. Link, Kathryn Z. Guyton, William C. Eckelman, Howard I. Scher, Joyce O'Shaughnessy, Bruce D. Cheson, Caroline C. Sigman, James L. Tatum, George Q. Mills, Daniel C. Sullivan, and Janet Woodcock
Clin Cancer Res 2005 11: 7967-7985. [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Clear Cell Sarcoma of the Kidney: Up-regulation of Neural Markers with Activation of the Sonic Hedgehog and Akt Pathways

Colleen Cutcliffe, Donna Kersey, Chiang-Ching Huang, Yong Zeng, David Walterhouse, Elizabeth J. Perlman for the Renal Tumor Committee of the Children's Oncology Group
Clin Cancer Res 2005 11: 7986-7994. [Abstract] [Full Text] [PDF]  

Heparanase Is Involved in Angiogenesis in Esophageal Cancer through Induction of Cyclooxygenase-2

Takaomi Okawa, Yoshio Naomoto, Tetsuji Nobuhisa, Munenori Takaoka, Takayuki Motoki, Yasuhiro Shirakawa, Tomoki Yamatsuji, Hiroyasu Inoue, Mamoru Ouchida, Mehmet Gunduz, Motowo Nakajima, and Noriaki Tanaka
Clin Cancer Res 2005 11: 7995-8005. [Abstract] [Full Text] [PDF]  

Changes in Cytoskeletal Protein Composition Indicative of an Epithelial-Mesenchymal Transition in Human Micrometastatic and Primary Breast Carcinoma Cells

Birthe Willipinski-Stapelfeldt, Sabine Riethdorf, Volker Assmann, Ute Woelfle, Thomas Rau, Guido Sauter, Jochen Heukeshoven, and Klaus Pantel
Clin Cancer Res 2005 11: 8006-8014. [Abstract] [Full Text] [PDF]  

Androgen Mediation of Thrombocytosis in Epithelial Ovarian Cancer Biology

Andrew John Li and Beth Young Karlan
Clin Cancer Res 2005 11: 8015-8018. [Abstract] [Full Text] [PDF]  

Overexpression of the Cytokine Osteopontin Identifies Aggressive Laryngeal Squamous Cell Carcinomas and Enhances Carcinoma Cell Proliferation and Invasiveness

Angela Celetti, Domenico Testa, Stefania Staibano, Francesco Merolla, Valentina Guarino, Maria Domenica Castellone, Renata Iovine, Gelsomina Mansueto, Pasquale Somma, Gaetano De Rosa, Vieri Galli, Rosa Marina Melillo, and Massimo Santoro
Clin Cancer Res 2005 11: 8019-8027. [Abstract] [Full Text] [PDF]  

Estrogen Signaling Is Active in Cartilaginous Tumors: Implications for Antiestrogen Therapy as Treatment Option of Metastasized or Irresectable Chondrosarcoma

Anne-Marie Cleton-Jansen, Hetty M. van Beerendonk, Hans J. Baelde, Judith V.G.M. Bovée, Marcel Karperien, and Pancras C.W. Hogendoorn
Clin Cancer Res 2005 11: 8028-8035. [Abstract] [Full Text] [PDF]  

Positive Correlation between Estradiol and Vascular Endothelial Growth Factor but not Fibroblast Growth Factor-2 in Normal Human Breast Tissue In vivo

Charlotta Dabrosin
Clin Cancer Res 2005 11: 8036-8041. [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Possible Prediction of Chemoradiosensitivity of Esophageal Cancer by Serum Protein Profiling

Yasuharu Hayashida, Kazufumi Honda, Yoshiaki Osaka, Tomohiko Hara, Tomoko Umaki, Akihiko Tsuchida, Tatsuya Aoki, Setsuo Hirohashi, and Tesshi Yamada
Clin Cancer Res 2005 11: 8042-8047. [Abstract] [Full Text] [PDF] Supplementary Data  

Specialized DNA Arrays for the Differentiation of Pancreatic Tumors

Malte Buchholz, Hans A. Kestler, Andrea Bauer, Wolfgang Böck, Bettina Rau, Gerhard Leder, Wolfgang Kratzer, Martin Bommer, Aldo Scarpa, Martin K. Schilling, Guido Adler, Jörg D. Hoheisel, and Thomas M. Gress
Clin Cancer Res 2005 11: 8048-8054. [Abstract] [Full Text] [PDF]  

Cancer-Testis Genes Are Coordinately Expressed and Are Markers of Poor Outcome in Non–Small Cell Lung Cancer

Ali O. Gure, Ramon Chua, Barbara Williamson, Mithat Gonen, Cathy A. Ferrera, Sacha Gnjatic, Gerd Ritter, Andrew J.G. Simpson, Yao-T. Chen, Lloyd J. Old, and Nasser K. Altorki
Clin Cancer Res 2005 11: 8055-8062. [Abstract] [Full Text] [PDF] Supplementary Data  

Increased Expression of Vascular Endothelial Growth Factor C in Papillary Thyroid Carcinoma Correlates with Cervical Lymph Node Metastases

Xiao-Min Yu, Chung-Yau Lo, Wai-Fan Chan, King-Yin Lam, Pauline Leung, and John M. Luk
Clin Cancer Res 2005 11: 8063-8069. [Abstract] [Full Text] [PDF]  

Transcription Repressor Slug Promotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma

Jin-Yuan Shih, Meng-Feng Tsai, Tzu-Hua Chang, Yih-Leong Chang, Ang Yuan, Chong-Jen Yu, Shin-Bey Lin, Geou-Yarh Liou, Meng-Larn Lee, Jeremy J.W. Chen, Tse-Ming Hong, Shuenn-Chen Yang, Jen-Liang Su, Yung-Chie Lee, and Pan-Chyr Yang
Clin Cancer Res 2005 11: 8070-8078. [Abstract] [Full Text] [PDF]  

Highly Sensitive Detection of Melanoma at an Early Stage Based on the Increased Serum Secreted Protein Acidic and Rich in Cysteine and Glypican-3 Levels

Yoshiaki Ikuta, Tetsuya Nakatsura, Toshiro Kageshita, Satoshi Fukushima, Shosuke Ito, Kazumasa Wakamatsu, Hideo Baba, and Yasuharu Nishimura
Clin Cancer Res 2005 11: 8079-8088. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Phase II Trial of Oral Aminopterin for Adults and Children with Refractory Acute Leukemia

Peter D. Cole, Richard A. Drachtman, Angela K. Smith, Sarah Cate, Richard A. Larson, Douglas S. Hawkins, John Holcenberg, Kara Kelly, and Barton A. Kamen
Clin Cancer Res 2005 11: 8089-8096. [Abstract] [Full Text] [PDF]  

Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 Polymorphisms with the Pharmacokinetics of Paclitaxel

Anja Henningsson, Sharon Marsh, Walter J. Loos, Mats O. Karlsson, Adam Garsa, Klaus Mross, Stephan Mielke, Lucia Viganò, Alberta Locatelli, Jaap Verweij, Alex Sparreboom, and Howard L. McLeod
Clin Cancer Res 2005 11: 8097-8104. [Abstract] [Full Text] [PDF]  

Response of Some Head and Neck Cancers to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors May Be Linked to Mutation of ERBB2 rather than EGFR

Ezra E.W. Cohen, Mark W. Lingen, Leslie E. Martin, Patricia L. Harris, Brian W. Brannigan, Sara M. Haserlat, Ross A. Okimoto, Dennis C. Sgroi, Sonika Dahiya, Beth Muir, John R. Clark, James W. Rocco, Everett E. Vokes, Daniel A. Haber, and Daphne W. Bell
Clin Cancer Res 2005 11: 8105-8108. [Abstract] [Full Text] [PDF]  

Predictors of Prostate Cancer Tissue Acquisition by an Undirected Core Bone Marrow Biopsy in Metastatic Castration-Resistant Prostate Cancer—A Cancer and Leukemia Group B Study

Robert W. Ross, Susan Halabi, San-San Ou, Barur R. Rajeshkumar, Bruce A. Woda, Nicholas J. Vogelzang, Eric J. Small, Mary-Ellen Taplin, and Philip W. Kantoff
Clin Cancer Res 2005 11: 8109-8113. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Comparison of Two Cancer Vaccines Targeting Tyrosinase: Plasmid DNA and Recombinant Alphavirus Replicon Particles

Stacie M. Goldberg, Shirley M. Bartido, Jason P. Gardner, José A. Guevara-Patiño, Stephanie C. Montgomery, Miguel-Angel Perales, Maureen F. Maughan, JoAnn Dempsey, Gerald P. Donovan, William C. Olson, Alan N. Houghton, and Jedd D. Wolchok
Clin Cancer Res 2005 11: 8114-8121. [Abstract] [Full Text] [PDF]  

Inhibition of the Met Receptor in Mesothelioma

Toru Mukohara, Gabriel Civiello, Ian J. Davis, Michele L. Taffaro, James Christensen, David E. Fisher, Bruce E. Johnson, and Pasi A. Jänne
Clin Cancer Res 2005 11: 8122-8130. [Abstract] [Full Text] [PDF]  

Combination Bcl-2 Antisense and Radiation Therapy for Nasopharyngeal Cancer

Kenneth W. Yip, Joseph D. Mocanu, P.Y. Billie Au, Gillian T. Sleep, Dolly Huang, Pierre Busson, Wen-Chen Yeh, Ralph Gilbert, Brian O'Sullivan, Patrick Gullane, Carlo Bastianutto, and Fei-Fei Liu
Clin Cancer Res 2005 11: 8131-8144. [Abstract] [Full Text] [PDF]  

ZD6474, a Novel Tyrosine Kinase Inhibitor of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor, Inhibits Tumor Growth of Multiple Nervous System Tumors

Jeremy N. Rich, Sith Sathornsumetee, Stephen T. Keir, Mark W. Kieran, Andrea Laforme, Arja Kaipainen, Roger E. McLendon, Michael W. Graner, B.K. Ahmed Rasheed, Ling Wang, David A. Reardon, Anderson J. Ryan, Catherine Wheeler, Isaiah Dimery, Darell D. Bigner, and Henry S. Friedman
Clin Cancer Res 2005 11: 8145-8157. [Abstract] [Full Text] [PDF]  

Roscovitine Modulates DNA Repair and Senescence: Implications for Combination Chemotherapy

Elvira Crescenzi, Giuseppe Palumbo, and Hugh J.M. Brady
Clin Cancer Res 2005 11: 8158-8171. [Abstract] [Full Text] [PDF]  

Heparin Octasaccharides Inhibit Angiogenesis In vivo

Jurjees Hasan, Steven D. Shnyder, Andrew R. Clamp, Alan T. McGown, Roy Bicknell, Marco Presta, Michael Bibby, John Double, Steven Craig, David Leeming, Kenneth Stevenson, John T. Gallagher, and Gordon C. Jayson
Clin Cancer Res 2005 11: 8172-8179. [Abstract] [Full Text] [PDF]  

Intraperitoneal Pretarget Radioimmunotherapy with CC49 Fusion Protein

Donald J. Buchsbaum, M.B. Khazaeli, Donald B. Axworthy, Jody Schultz, Tandra R. Chaudhuri, Kurt R. Zinn, Mark Carpenter, and Albert F. LoBuglio
Clin Cancer Res 2005 11: 8180-8185. [Abstract] [Full Text] [PDF]  

Inhibition of Nuclear Translocation of Nuclear Factor-B Despite Lack of Functional IB Protein Overcomes Multiple Defects in Apoptosis Signaling in Human B-Cell Malignancies

Roman K. Thomas, Martin L. Sos, Thomas Zander, Özlem Mani, Alexey Popov, Daniel Berenbrinker, Sigrun Smola-Hess, Joachim L. Schultze, and Jürgen Wolf
Clin Cancer Res 2005 11: 8186-8194. [Abstract] [Full Text] [PDF]  

Effect of the Selective Estrogen Receptor Modulator Arzoxifene on Repopulation of Hormone-Responsive Breast Cancer Xenografts between Courses of Chemotherapy

Licun Wu and Ian F. Tannock
Clin Cancer Res 2005 11: 8195-8200. [Abstract] [Full Text] [PDF]  

Carbonic Anhydrase II Is a Tumor Vessel Endothelium–Associated Antigen Targeted by Dendritic Cell Therapy

Kenta Yoshiura, Takashi Nakaoka, Toshihide Nishishita, Katsuaki Sato, Akifumi Yamamoto, Shinji Shimada, Toshiaki Saida, Yutaka Kawakami, Tsuneo A. Takahashi, Hiroyuki Fukuda, Shinobu Imajoh-Ohmi, Naoki Oyaizu, and Naohide Yamashita
Clin Cancer Res 2005 11: 8201-8207. [Abstract] [Full Text] [PDF]  

Phosphatidylinostol 3-Kinase Mediates Angiogenesis and Vascular Permeability Associated with Ovarian Carcinoma

Limin Hu, Judith Hofmann, and Robert B. Jaffe
Clin Cancer Res 2005 11: 8208-8212. [Abstract] [Full Text] [PDF]  

Cancer Prevention:

In vitro and In vivo Effects and Mechanisms of Celecoxib-Induced Growth Inhibition of Human Hepatocellular Carcinoma Cells

Wei Cui, Chang-Hong Yu, and Ke-Qin Hu
Clin Cancer Res 2005 11: 8213-8221. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

The Estrogen Receptors , ß, and ßcx

Abeer M. Shaaban, Valerie Speirs, Henri Rochefort, and Majida Esslimani-Sahla
Clin Cancer Res 2005 11: 8222-8223. [Full Text] [PDF]  

Corrections:

Article on Sodium Channels and Breast Cancer Metastasis

Clin Cancer Res 2005 11: 8224. [Full Text] [PDF]  

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