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Contents: January 15 2005, Volume 11, Issue 2   [Index by Author] 
    Perspective
    Cooperative Group Bulletin Board
    Human Cancer Biology
    Imaging, Diagnosis, Prognosis
    Cancer Therapy: Clinical
    Cancer Therapy: Preclinical
    Letter to the Editor
    Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer
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Perspective:

Concepts for Banking Tissue in Urologic Oncology—The International Bladder Cancer Bank
Peter J. Goebell, Susan Groshen, Bernd J. Schmitz-Dräger, Richard Sylvester, Manolis Kogevinas, Núria Malats, Guido Sauter, H. Barton Grossman, Colin P.N. Dinney, Fred Waldman, and Richard J. Cote
Clin Cancer Res 2005 11: 413-415. [Full Text] [PDF]  

Differentiation and Definition of Vascular-Targeted Therapies
Dietmar W. Siemann, Michael C. Bibby, Graham G. Dark, Adam P. Dicker, Ferry A.L.M. Eskens, Michael R. Horsman, Dieter Marmé, and Patricia M. LoRusso
Clin Cancer Res 2005 11: 416-420. [Abstract] [Full Text] [PDF]  

Cooperative Group Bulletin Board:

New Frontiers in Translational Research in Neuro-oncology and the Blood-Brain Barrier: Report of the Tenth Annual Blood-Brain Barrier Disruption Consortium Meeting
Nancy D. Doolittle, Lauren E. Abrey, W. Archie Bleyer, Steven Brem, Thomas P. Davis, Paula Dore-Duffy, Lester R. Drewes, Walter A. Hall, John M. Hoffman, Agnieszka Korfel, Robert Martuza, Leslie L. Muldoon, David Peereboom, Darryl R. Peterson, Samuel D. Rabkin, Quentin Smith, Glen H.J. Stevens, and Edward A. Neuwelt
Clin Cancer Res 2005 11: 421-428. [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Geranylgeranylated Proteins are Involved in the Regulation of Myeloma Cell Growth
Niels W.C.J. van de Donk, Henk M. Lokhorst, Evert H.J. Nijhuis, Marloes M.J. Kamphuis, and Andries C. Bloem
Clin Cancer Res 2005 11: 429-439. [Abstract] [Full Text] [PDF]  

Overexpression of Tropomysin-Related Kinase B in Metastatic Human Pancreatic Cancer Cells
Guido M. Sclabas, Shuichi Fujioka, Christian Schmidt, Zhongkui Li, Wayne A.I. Frederick, Wentao Yang, Kenji Yokoi, Douglas B. Evans, James L. Abbruzzese, Kenneth R. Hess, Wei Zhang, Isaiah J. Fidler, and Paul J. Chiao
Clin Cancer Res 2005 11: 440-449. [Abstract] [Full Text] [PDF]  

Aberrant Expression of Human Achaete-Scute Homologue Gene 1 in the Gastrointestinal Neuroendocrine Carcinomas
Takashi Shida, Mitsuko Furuya, Takashi Nikaido, Takashi Kishimoto, Keiji Koda, Kenji Oda, Yukio Nakatani, Masaru Miyazaki, and Hiroshi Ishikura
Clin Cancer Res 2005 11: 450-458. [Abstract] [Full Text] [PDF]  

Fibroblast Growth Factor Receptor 3 Is Overexpressed in Urinary Tract Carcinomas and Modulates the Neoplastic Cell Growth
J. Javier Gómez-Román, Pilar Saenz, Jorge Cuevas González, Kepa Escuredo, Simon Santa Cruz, Corina Junquera, Laureano Simón, Antonio Martínez, J. Luis Gutiérrez Baños, Marta López-Brea, Clara Esparza, and J. Fernando Val-Bernal
Clin Cancer Res 2005 11: 459-465. [Abstract] [Full Text] [PDF]  

Plasma Adiponectin and Gastric Cancer
Makoto Ishikawa, Joji Kitayama, Shinsuke Kazama, Takeyuki Hiramatsu, Kenji Hatano, and Hirokazu Nagawa
Clin Cancer Res 2005 11: 466-472. [Abstract] [Full Text] [PDF]  

Identification of Gastric Cancer–Related Genes Using a cDNA Microarray Containing Novel Expressed Sequence Tags Expressed in Gastric Cancer Cells
Jeong-Min Kim, Ho-Yong Sohn, Sun Young Yoon, Jung-Hwa Oh, Jin Ok Yang, Joo Heon Kim, Kyu Sang Song, Seung-Moo Rho, Hyan Sook Yoo, Yong Sung Kim, Jong-Guk Kim, and Nam-Soon Kim
Clin Cancer Res 2005 11: 473-482. [Abstract] [Full Text] [PDF]  

Alternative mRNA Splicing of Liver Intestine-Cadherin in Hepatocellular Carcinoma
Xiao Qi Wang, John M. Luk, Pauline P. Leung, Bonnie W. Wong, Eric J. Stanbridge, and Sheung Tat Fan
Clin Cancer Res 2005 11: 483-489. [Abstract] [Full Text] [PDF]  

Involvement of Chemokine Receptor 4/Stromal Cell–Derived Factor 1 System during Osteosarcoma Tumor Progression
Eliana Perissinotto, Giuliana Cavalloni, Francesco Leone, Valentina Fonsato, Stefania Mitola, Giovanni Grignani, Nadia Surrenti, Dario Sangiolo, Federico Bussolino, Wanda Piacibello, and Massimo Aglietta
Clin Cancer Res 2005 11: 490-497. [Abstract] [Full Text] [PDF]  

Control of T-Cell–Mediated Immune Response by HLA Class I in Human Pancreatic Carcinoma
Eduard Ryschich, Tanja Nötzel, Ulf Hinz, Frank Autschbach, James Ferguson, Ioan Simon, Jürgen Weitz, Boris Fröhlich, Ernst Klar, Markus W. Büchler, and Jan Schmidt
Clin Cancer Res 2005 11: 498-504. [Abstract] [Full Text] [PDF]  

CD34+CD7+ Leukemic Progenitor Cells May Be Involved in Maintenance and Clonal Evolution of Chronic Myeloid Leukemia
Nobuharu Kosugi, Yasuhiro Ebihara, Tatsutoshi Nakahata, Hiromitsu Saisho, Shigetaka Asano, and Arinobu Tojo
Clin Cancer Res 2005 11: 505-511. [Abstract] [Full Text] [PDF]  

Mutations and Deletions of the CBP Gene in Human Lung Cancer
Masahiro Kishimoto, Takashi Kohno, Koji Okudela, Ayaka Otsuka, Hiroki Sasaki, Chikako Tanabe, Tokuki Sakiyama, Chie Hirama, Issay Kitabayashi, John D. Minna, Seiichi Takenoshita, and Jun Yokota
Clin Cancer Res 2005 11: 512-519. [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Expression and Signaling Activity of Wnt-5a/Discoidin Domain Receptor-1 and Syk Plays Distinct but Decisive Roles in Breast Cancer Patient Survival
Janna Dejmek, Karin Leandersson, Jonas Manjer, Anders Bjartell, Stefan O. Emdin, Wolfgang F. Vogel, Göran Landberg, and Tommy Andersson
Clin Cancer Res 2005 11: 520-528. [Abstract] [Full Text] [PDF]  

The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resonance Imaging
Bénédicte F. Jordan, Matthew Runquist, Natarajan Raghunand, Robert J. Gillies, Wendy R. Tate, Garth Powis, and Amanda F. Baker
Clin Cancer Res 2005 11: 529-536. [Abstract] [Full Text] [PDF]  

The Natural Course of Preneoplastic Lesions in Bronchial Epithelium
Roderick H. Breuer, Arifa Pasic, Egbert F. Smit, Esther van Vliet, Anton Vonk Noordegraaf, Elle J. Risse, Pieter E. Postmus, and Thomas G. Sutedja
Clin Cancer Res 2005 11: 537-543. [Abstract] [Full Text] [PDF]  

Tartrate-Resistant Acid Phosphatase 5b is a Useful Serum Marker for Extensive Bone Metastasis in Breast Cancer Patients
Tsu-Yi Chao, Jyh-Cherng Yu, Chih-Hung Ku, Mary M. Chen, Su-Huei Lee, Anthony J. Janckila, and Lung T. Yam
Clin Cancer Res 2005 11: 544-550. [Abstract] [Full Text] [PDF]  

Claudin-10 Expression Level is Associated with Recurrence of Primary Hepatocellular Carcinoma
Siu Tim Cheung, Ka Ling Leung, Ying Chi Ip, Xin Chen, Daniel Y. Fong, Irene O. Ng, Sheung Tat Fan, and Samuel So
Clin Cancer Res 2005 11: 551-556. [Abstract] [Full Text] [PDF] Supplementary Data  

Methylation of the {gamma}-Catenin Gene Is Associated With Poor Prognosis of Renal Cell Carcinoma
Julia E. Breault, Hiroaki Shiina, Mikio Igawa, Leopoldo A. Ribeiro-Filho, Masao Deguchi, Hideki Enokida, Shinji Urakami, Masaharu Terashima, Masayuki Nakagawa, Christopher J. Kane, Peter R. Carroll, and Rajvir Dahiya
Clin Cancer Res 2005 11: 557-564. [Abstract] [Full Text] [PDF]  

Interlaboratory Comparability Study of Cancer Gene Expression Analysis Using Oligonucleotide Microarrays
Kevin K. Dobbin, David G. Beer, Matthew Meyerson, Timothy J. Yeatman, William L. Gerald, James W. Jacobson, Barbara Conley, Kenneth H. Buetow, Mervi Heiskanen, Richard M. Simon, John D. Minna, Luc Girard, David E. Misek, Jeremy M.G. Taylor, Samir Hanash, Katsuhiko Naoki, D. Neil Hayes, Christine Ladd-Acosta, Steven A. Enkemann, Agnes Viale, and Thomas J. Giordano
Clin Cancer Res 2005 11: 565-572. [Abstract] [Full Text] [PDF] Supplementary Data  

Age- and Disease-Related Methylation of Multiple Genes in Nonneoplastic Duodenum and in Duodenal Juice
Hiroyuki Matsubayashi, Norihiro Sato, Kieran Brune, Amanda Lapides Blackford, Ralph H. Hruban, Marcia Canto, Charles J. Yeo, and Michael Goggins
Clin Cancer Res 2005 11: 573-583. [Abstract] [Full Text] [PDF]  

Stage-Specific Characterization of the Vascular Endothelial Growth Factor Axis in Prostate Cancer: Expression of Lymphangiogenic Markers Is Associated with Advanced-Stage Disease
Varsha Kaushal, Perkins Mukunyadzi, Richard A. Dennis, Eric R. Siegel, Donald E. Johnson, and Manish Kohli
Clin Cancer Res 2005 11: 584-593. [Abstract] [Full Text] [PDF]  

Prognostic Significance of MMP-1 and MMP-3 Functional Promoter Polymorphisms in Colorectal Cancer
Franck Zinzindohoué, Thierry Lecomte, Jean-Marc Ferraz, Anne-Marie Houllier, Paul-Henri Cugnenc, Anne Berger, Hélène Blons, and Pierre Laurent-Puig
Clin Cancer Res 2005 11: 594-599. [Abstract] [Full Text] [PDF]  

Epidermal Growth Factor Receptor Gene Polymorphisms Predict Pelvic Recurrence in Patients with Rectal Cancer Treated with Chemoradiation
Wu Zhang, David J. Park, Bo Lu, Dong Yun Yang, Michael Gordon, Susan Groshen, Jim Yun, Oliver A. Press, Daniel Vallböhmer, Katrin Rhodes, and Heinz-Josef Lenz
Clin Cancer Res 2005 11: 600-605. [Abstract] [Full Text] [PDF]  

Down-Regulation of S100C Is Associated with Bladder Cancer Progression and Poor Survival
Ashfaque Ahmed Memon, Boe Sandahl Sorensen, Peter Meldgaard, Lars Fokdal, Thomas Thykjaer, and Ebba Nexo
Clin Cancer Res 2005 11: 606-611. [Abstract] [Full Text] [PDF]  

Gene Copy Number Change Events at Chromosome 20 and Their Association with Recurrence in Gastric Cancer Patients
Sang Hwa Yang, Min Young Seo, Ha Jin Jeong, Hei-Cheul Jeung, Jihye Shin, Sang Chul Kim, Sung Hoon Noh, Hyun Cheol Chung, and Sun Young Rha
Clin Cancer Res 2005 11: 612-620. [Abstract] [Full Text] [PDF]  

Classic and Molecular Cytogenetic Analyses Reveal Chromosomal Gains and Losses Correlated with Survival in Head and Neck Cancer Patients
Nádia Aparecida Bérgamo, Luciana Caricati da Silva Veiga, Patricia Pintor dos Reis, Inês Nobuko Nishimoto, José Magrin, Luiz Paulo Kowalski, Jeremy A. Squire, and Sílvia Regina Rogatto
Clin Cancer Res 2005 11: 621-631. [Abstract] [Full Text] [PDF]  

Subcellular Localization of p27kip1 Expression Predicts Poor Prognosis in Human Ovarian Cancer
Daniel G. Rosen, Gong Yang, Kathy Qi Cai, Robert C. Bast, Jr., David M. Gershenson, Elvio G. Silva, and Jinsong Liu
Clin Cancer Res 2005 11: 632-637. [Abstract] [Full Text] [PDF]  

Loss of p16 Protein Defines High-Risk Patients with Gastrointestinal Stromal Tumors: A Tissue Microarray Study
Regine Schneider-Stock, Carsten Boltze, Jerzy Lasota, Brigitte Peters, Chris L. Corless, Petra Ruemmele, Luigi Terracciano, Matthias Pross, Luigi Insabato, Dolores Di Vizio, Igor Iesalnieks, Stefan Dirnhofer, Arndt Hartmann, Michel Heinrich, Markku Miettinen, Albert Roessner, and Luigi Tornillo
Clin Cancer Res 2005 11: 638-645. [Abstract] [Full Text] [PDF]  

Gene Expression in Kidney Cancer Is Associated with Cytogenetic Abnormalities, Metastasis Formation, and Patient Survival
Holger Sültmann, Anja von Heydebreck, Wolfgang Huber, Ruprecht Kuner, Andreas Buneß, Markus Vogt, Bastian Gunawan, Martin Vingron, Laszlo Füzesí, and Annemarie Poustka
Clin Cancer Res 2005 11: 646-655. [Abstract] [Full Text] [PDF] Supplementary Data  

Prognostic Significance of CpG Island Methylator Phenotype and Microsatellite Instability in Gastric Carcinoma
Changhyeok An, In-Seon Choi, James C. Yao, Samidha Worah, Keping Xie, Paul F. Mansfield, Jaffer A. Ajani, Asif Rashid, Stanley R. Hamilton, and Tsung-Teh Wu
Clin Cancer Res 2005 11: 656-663. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

A Phase I and Pharmacokinetic Study of Short Infusions of UCN-01 in Patients with Refractory Solid Tumors
E. Claire Dees, Sharyn D. Baker, Seamus O'Reilly, Michelle A. Rudek, Susan B. Davidson, Cheryl Aylesworth, Kathy Elza-Brown, Michael A. Carducci, and Ross C. Donehower
Clin Cancer Res 2005 11: 664-671. [Abstract] [Full Text] [PDF]  

A Phase I and Pharmacokinetic Study of Ecteinascidin-743 (Yondelis) in Children with Refractory Solid Tumors. A Children's Oncology Group Study
Loretta Lau, Jeffery G. Supko, Susan Blaney, Linda Hershon, Nita Seibel, Mark Krailo, Wenchun Qu, David Malkin, Jose Jimeno, Mark Bernstein, Sylvain Baruchel for the Children's Oncology Group
Clin Cancer Res 2005 11: 672-677. [Abstract] [Full Text] [PDF]  

Pharmacodynamic Analysis of Target Inhibition and Endothelial Cell Death in Tumors Treated with the Vascular Endothelial Growth Factor Receptor Antagonists SU5416 or SU6668
Darren W. Davis, Ryan Takamori, Chandrajit P. Raut, Henry Q. Xiong, Roy S. Herbst, Walter M. Stadler, John V. Heymach, George D. Demetri, Asif Rashid, Yu Shen, Sijin Wen, James L. Abbruzzese, and David J. McConkey
Clin Cancer Res 2005 11: 678-689. [Abstract] [Full Text] [PDF]  

Pemetrexed Combined with Oxaliplatin or Carboplatin as First-Line Treatment in Advanced Non–Small Cell Lung Cancer: A Multicenter, Randomized, Phase II Trial
Giorgio V. Scagliotti, Cornelius Kortsik, Graham G. Dark, Allan Price, Christian Manegold, Rafael Rosell, Mary O'Brien, Patrick M. Peterson, Daniel Castellano, Giovanni Selvaggi, Silvia Novello, Johannes Blatter, Louis Kayitalire, Lucio Crino, and Luis Paz-Ares
Clin Cancer Res 2005 11: 690-696. [Abstract] [Full Text] [PDF]  

Phase I/II Study of the Rituximab-EPOCT Regimen in Combination with Granulocyte Colony-Stimulating Factor in Patients with Relapsed or Refractory Follicular Lymphoma Including Evaluation of Its Cardiotoxicity Using B-Type Natriuretic Peptide and Troponin T Levels
Nozomi Niitsu, Mika Khori, Miyuki Hayama, Koichi Kajiwara, Masaaki Higashihara, and Jun-ichi Tamaru
Clin Cancer Res 2005 11: 697-702. [Abstract] [Full Text] [PDF]  

Phase I and Pharmacokinetic Study of DE-310 in Patients with Advanced Solid Tumors
Otto Soepenberg, Maja J. A. de Jonge, Alex Sparreboom, Peter de Bruin, Ferry A. L. M. Eskens, Gerda de Heus, Jantien Wanders, Peter Cheverton, Murray P. Ducharme, and Jaap Verweij
Clin Cancer Res 2005 11: 703-711. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Targeting Cyclooxygenase-2 Reduces Overt Toxicity toward Low-Dose Vinblastine and Extends Survival of Juvenile Mice with Friend Disease
Dave Cervi, Giannoula Klement, Diana Stempak, Sylvain Baruchel, Alane Koki, and Yaacov Ben-David
Clin Cancer Res 2005 11: 712-719. [Abstract] [Full Text] [PDF]  

Effect of Tumor Host Microenvironment on Photodynamic Therapy in a Rat Prostate Tumor Model
Bin Chen, Brian W. Pogue, Xiaodong Zhou, Julia A. O'Hara, Nicolas Solban, Eugene Demidenko, P. Jack Hoopes, and Tayyaba Hasan
Clin Cancer Res 2005 11: 720-727. [Abstract] [Full Text] [PDF]  

Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer
Sandra Demaria, Noriko Kawashima, Anne Marie Yang, Mary Louise Devitt, James S. Babb, James P. Allison, and Silvia C. Formenti
Clin Cancer Res 2005 11: 728-734. [Abstract] [Full Text] [PDF]  

Sequential Immunogene Therapy with Interleukin-12– and Interleukin-15–Engineered Neuroblastoma Cells Cures Metastatic Disease in Syngeneic Mice
Michela Croce, Raffaella Meazza, Anna Maria Orengo, Luana Radic', Barbara De Giovanni, Claudio Gambini, Barbara Carlini, Vito Pistoia, Lorenzo Mortara, Roberto S. Accolla, Maria Valeria Corrias, and Silvano Ferrini
Clin Cancer Res 2005 11: 735-742. [Abstract] [Full Text] [PDF]  

Thalidomide Radiosensitizes Tumors through Early Changes in the Tumor Microenvironment
Réginald Ansiaux, Christine Baudelet, Bénédicte F. Jordan, Nelson Beghein, Pierre Sonveaux, Julie De Wever, Philippe Martinive, Vincent Grégoire, Olivier Feron, and Bernard Gallez
Clin Cancer Res 2005 11: 743-750. [Abstract] [Full Text] [PDF]  

Clinical Evaluation of BR96 sFv-PE40 Immunotoxin Therapy in Canine Models of Spontaneously Occurring Invasive Carcinoma
Carolyn J. Henry, Michael S. Buss, Ingegerd Hellström, Karl Erik Hellström, William G. Brewer, Jeffrey N. Bryan, and Clay B. Siegall
Clin Cancer Res 2005 11: 751-755. [Abstract] [Full Text] [PDF]  

Intracellular Localization and Trafficking of Fluorescein-Labeled Cisplatin in Human Ovarian Carcinoma Cells
Roohangiz Safaei, Kuniyuki Katano, Barrett J. Larson, Goli Samimi, Alison K. Holzer, Wiltrud Naerdemann, Mika Tomioka, Murray Goodman, and Stephen B. Howell
Clin Cancer Res 2005 11: 756-767. [Abstract] [Full Text] [PDF]  

Continuous Delivery of Endogenous Inhibitors from Poly(Lactic-Co-Glycolic Acid) Polymeric Microspheres Inhibits Glioma Tumor Growth
Ofra Benny, Maayan Duvshani-Eshet, Theresa Cargioli, Lorenzo Bello, Andreas Bikfalvi, Rona S. Carroll, and Marcelle Machluf
Clin Cancer Res 2005 11: 768-776. [Abstract] [Full Text] [PDF]  

Therapy of Small Subcutaneous B-Lymphoma Xenografts with Antibodies Conjugated to Radionuclides Emitting Low-Energy Electrons
Rosana B. Michel, Adriane V. Rosario, Philip M. Andrews, David M. Goldenberg, and M. Jules Mattes
Clin Cancer Res 2005 11: 777-786. [Abstract] [Full Text] [PDF]  

Biodistribution of Yttrium-90–Labeled Anti-CD45 Antibody in a Nonhuman Primate Model
Eneida R. Nemecek, Donald K. Hamlin, Darrell R. Fisher, Kenneth A. Krohn, John M. Pagel, Frederick R. Appelbaum, Oliver W. Press, and Dana C. Matthews
Clin Cancer Res 2005 11: 787-794. [Abstract] [Full Text] [PDF]  

The Effects of Cetuximab Alone and in Combination With Radiation and/or Chemotherapy in Lung Cancer
David Raben, Barb Helfrich, Daniel C. Chan, Fortunato Ciardiello, LiMin Zhao, Wilbur Franklin, Anna E. Barón, Chan Zeng, Tim K. Johnson, and Paul A. Bunn, Jr
Clin Cancer Res 2005 11: 795-805. [Abstract] [Full Text] [PDF]  

Adenoviral Transduction of TESTIN Gene into Breast and Uterine Cancer Cell Lines Promotes Apoptosis and Tumor Reduction In vivo
Manuela Sarti, Cinzia Sevignani, George A. Calin, Rami Aqeilan, Masayoshi Shimizu, Francesca Pentimalli, Maria Cristina Picchio, Andrew Godwin, Anne Rosenberg, Alessandra Drusco, Massimo Negrini, and Carlo M. Croce
Clin Cancer Res 2005 11: 806-813. [Abstract] [Full Text] [PDF]  

Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy
Surinder K. Sharma, R. Barbara Pedley, Jeetendra Bhatia, Geoffrey M. Boxer, Ethaar El-Emir, Uzma Qureshi, Berend Tolner, Helen Lowe, N. Paul Michael, Nigel Minton, Richard H. J. Begent, and Kerry A. Chester
Clin Cancer Res 2005 11: 814-825. [Abstract] [Full Text] [PDF]  

Mathematical Modeling and Optimization of Drug Delivery from Intratumorally Injected Microspheres
Abraham Rami Tzafriri, Elyakum Itzhak Lerner, Moshe Flashner-Barak, Michael Hinchcliffe, Eli Ratner, and Hanna Parnas
Clin Cancer Res 2005 11: 826-834. [Abstract] [Full Text] [PDF] Supplementary Data  

Effect of the Tumor Vascular-Damaging Agent, ZD6126, on the Radioresponse of U87 Glioblastoma
Phyllis R. Wachsberger, Randy Burd, Nichol Marero, Constantine Daskalakis, Anderson Ryan, Peter McCue, and Adam P. Dicker
Clin Cancer Res 2005 11: 835-842. [Abstract] [Full Text] [PDF]  

In vivo Drug-Linker Stability of an Anti-CD30 Dipeptide-Linked Auristatin Immunoconjugate
Russell J. Sanderson, Michelle A. Hering, Stephanie F. James, Michael M.C. Sun, Svetlana O. Doronina, Anthony W. Siadak, Peter D. Senter, and Alan F. Wahl
Clin Cancer Res 2005 11: 843-852. [Abstract] [Full Text] [PDF]  

A Third-Generation Bisphosphonate, Minodronic Acid (YM529), Augments the Interferon {alpha}/ß-Mediated Inhibition of Renal Cell Cancer Cell Growth Both In vitro and In vivo
Takeshi Yuasa, Masaki Nogawa, Shinya Kimura, Asumi Yokota, Kiyoshi Sato, Hidekazu Segawa, Junya Kuroda, and Taira Maekawa
Clin Cancer Res 2005 11: 853-859. [Abstract] [Full Text] [PDF]  

Letter to the Editor:

Telomere Length Abnormalities and Human Cancer
Katharina Schroecksnadel, Florian Ueberall, and Dietmar Fuchs
Clin Cancer Res 2005 11: 860. [Full Text] [PDF]  

Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer:

Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: Conference Summary Statement
Steven E. Come, Aman U. Buzdar, James N. Ingle, Carlos L. Arteaga, Angela M. Brodie, Graham A. Colditz, Stephen R.D. Johnston, Vessela N. Kristensen, Per E. Lønning, Donald P. McDonnell, C. Kent Osborne, Jose Russo, Richard J. Santen, Douglas Yee, and Carol S. Hart
Clin Cancer Res 2005 11: 861S-864S. [Full Text] [PDF]  

Crosstalk between Estrogen Receptor and Growth Factor Receptor Pathways as a Cause for Endocrine Therapy Resistance in Breast Cancer
C. Kent Osborne, Jiang Shou, Suleiman Massarweh, and Rachel Schiff
Clin Cancer Res 2005 11: 865S-870S. [Abstract] [Full Text] [PDF]  

The Molecular Pharmacology of Estrogen Receptor Modulators: Implications for the Treatment of Breast Cancer
Donald P. McDonnell
Clin Cancer Res 2005 11: 871S-877S. [Abstract] [Full Text] [PDF]  

Gene Expression Profiling of Breast Cancer in Relation to Estrogen Receptor Status and Estrogen-Metabolizing Enzymes: Clinical Implications
Vessela N. Kristensen, Therese Sørlie, Jurgen Geisler, Anita Langerød, Noriko Yoshimura, Rolf Kåresen, Nobuhiro Harada, P.E. Lønning, and Anne-Lise Børresen-Dale
Clin Cancer Res 2005 11: 878S-883S. [Abstract] [Full Text] [PDF]  

Therapeutic Observations in MCF-7 Aromatase Xenografts
Angela Brodie, Danijela Jelovac, Luciana Macedo, Gauri Sabnis, Syreeta Tilghman, and Olga Goloubeva
Clin Cancer Res 2005 11: 884S-888S. [Abstract] [Full Text] [PDF]  

Combinations of Endocrine and Biological Agents: Present Status of Therapeutic and Presurgical Investigations
Stephen RD Johnston
Clin Cancer Res 2005 11: 889S-899S. [Abstract] [Full Text] [PDF]  

Endocrine Therapy Trials of Aromatase Inhibitors for Breast Cancer in the Adjuvant and Prevention Settings
James N. Ingle
Clin Cancer Res 2005 11: 900S-905S. [Abstract] [Full Text] [PDF]  

TAS-108: A Novel Steroidal Antiestrogen
Aman U. Buzdar
Clin Cancer Res 2005 11: 906S-908S. [Abstract] [Full Text] [PDF]  

Estrogen, Estrogen Plus Progestin Therapy, and Risk of Breast Cancer
Graham A. Colditz
Clin Cancer Res 2005 11: 909S-917S. [Abstract] [Full Text] [PDF]  

Exemestane for Breast Cancer Prevention: A Feasible Strategy?
Per E. Lønning
Clin Cancer Res 2005 11: 918S-924S. [Abstract] [Full Text] [PDF]  

Tamoxifen versus Aromatase Inhibitors for Breast Cancer Prevention
Wei Yue, Ji-Ping Wang, Yuebai Li, Wayne P. Bocchinfuso, Kenneth S. Korach, Prabu D. Devanesan, Eleanor Rogan, Ercole Cavalieri, and Richard J. Santen
Clin Cancer Res 2005 11: 925S-930S. [Abstract] [Full Text] [PDF]  

Breast Differentiation and Its Implication in Cancer Prevention
Jose Russo, Daniel Mailo, Yun-Fu Hu, Gabriela Balogh, Fathima Sheriff, and Irma H. Russo
Clin Cancer Res 2005 11: 931S-936S. [Abstract] [Full Text] [PDF]  

Dual Role of Transforming Growth Factor ß in Mammary Tumorigenesis and Metastatic Progression
Rebecca S. Muraoka-Cook, Nancy Dumont, and Carlos L. Arteaga
Clin Cancer Res 2005 11: 937S-943S. [Abstract] [Full Text] [PDF]  

Insulin-Like Growth Factor-I and Breast Cancer Therapy
Yasir H. Ibrahim and Douglas Yee
Clin Cancer Res 2005 11: 944S-950S. [Abstract] [Full Text] [PDF]  

Short-Term Changes in Ki-67 during Neoadjuvant Treatment of Primary Breast Cancer with Anastrozole or Tamoxifen Alone or Combined Correlate with Recurrence-Free Survival
Mitch Dowsett, Ian E. Smith, Steve R. Ebbs, J. Michael Dixon, Anthony Skene, Clive Griffith, Irene Boeddinghaus, Janine Salter, Simone Detre, Margaret Hills, Susan Ashley, Stephen Francis, Geraldine Walsh on behalf of the IMPACT Trialists
Clin Cancer Res 2005 11: 951S-958S. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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Copyright © 2005 by the American Association for Cancer Research.