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Contents: August 15 2005, Volume 11, Issue 16   [Index by Author] 
    Editorials
    The Biology Behind
    Report from the FDA
    Human Cancer Biology
    Imaging, Diagnosis, Prognosis
    Cancer Therapy: Clinical
    Cancer Therapy: Preclinical
    Cancer Prevention
    Letters to the Editor
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Editorials:

Phase II Oncology Trials: Let's Be Positive
Mark J. Ratain
Clin Cancer Res 2005 11: 5661-5662. [Full Text] [PDF]  

Personalized, Multivalent, and More Affordable: The Globalization of Vaccines
Waldemar Debinski
Clin Cancer Res 2005 11: 5663-5664. [Full Text] [PDF]  

The Biology Behind:

Cyclin D1 and Pancreatic Carcinoma: A Proliferative Agonist and Chemotherapeutic Antagonist
J. Alan Diehl and Sharon Benzeno
Clin Cancer Res 2005 11: 5665-5667. [Full Text] [PDF]  

Epidermal Growth Factor Receptor Mutations in Non–Small Cell Lung Cancer: Predicting Clinical Response to Kinase Inhibitors
Lecia V. Sequist, Daniel A. Haber, and Thomas J. Lynch
Clin Cancer Res 2005 11: 5668-5670. [Full Text] [PDF]  

Report from the FDA:

Letrozole in the Extended Adjuvant Treatment of Postmenopausal Women with History of Early-Stage Breast Cancer Who Have Completed 5 Years of Adjuvant Tamoxifen
Bhupinder S. Mann, John R. Johnson, Roswitha Kelly, Rajeshwari Sridhara, Grant Williams, and Richard Pazdur
Clin Cancer Res 2005 11: 5671-5677. [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy
Roman Rouzier, Charles M. Perou, W. Fraser Symmans, Nuhad Ibrahim, Massimo Cristofanilli, Keith Anderson, Kenneth R. Hess, James Stec, Mark Ayers, Peter Wagner, Paolo Morandi, Chang Fan, Islam Rabiul, Jeffrey S. Ross, Gabriel N. Hortobagyi, and Lajos Pusztai
Clin Cancer Res 2005 11: 5678-5685. [Abstract] [Full Text] [PDF] Supplementary Data  

CCR7 and CXCR4 as Novel Biomarkers Predicting Axillary Lymph Node Metastasis in T1 Breast Cancer
Neslihan Cabioglu, M. Sertac Yazici, Banu Arun, Kristine R. Broglio, Gabriel N. Hortobagyi, Janet E. Price, and Aysegul Sahin
Clin Cancer Res 2005 11: 5686-5693. [Abstract] [Full Text] [PDF]  

Tissue Distribution of Human Papillomavirus 16 DNA Integration in Patients with Tonsillar Carcinoma
Shahnaz Begum, Dengfeng Cao, Maura Gillison, Marianna Zahurak, and William H. Westra
Clin Cancer Res 2005 11: 5694-5699. [Abstract] [Full Text] [PDF]  

A Comparison Study of Different PCR Assays in Measuring Circulating Plasma Epstein-Barr Virus DNA Levels in Patients with Nasopharyngeal Carcinoma
Quynh-Thu Le, Carol D. Jones, Tsz-Kok Yau, Haider A. Shirazi, Priscilla H. Wong, Ella N. Thomas, Bruce K. Patterson, Anne W.M. Lee, and James L. Zehnder
Clin Cancer Res 2005 11: 5700-5707. [Abstract] [Full Text] [PDF]  

Expression of Functional B7-H2 and B7.2 Costimulatory Molecules and Their Prognostic Implications in De novo Acute Myeloid Leukemia
Hideto Tamura, Kazuo Dan, Koji Tamada, Kyoko Nakamura, Yumiko Shioi, Hideya Hyodo, Sheng-Dian Wang, Haidong Dong, Lieping Chen, and Kiyoyuki Ogata
Clin Cancer Res 2005 11: 5708-5717. [Abstract] [Full Text] [PDF]  

Interleukin-1 and Interleukin-6 Gene Polymorphisms and the Risk of Breast Cancer in Caucasian Women
Lukas A. Hefler, Christoph Grimm, Tilmann Lantzsch, Dieter Lampe, Sepp Leodolter, Heinz Koelbl, Georg Heinze, Alexander Reinthaller, Dan Tong-Cacsire, Clemens Tempfer, and Robert Zeillinger
Clin Cancer Res 2005 11: 5718-5721. [Abstract] [Full Text] [PDF]  

Identification of Two Molecular Groups of Seminomas by Using Expression and Tissue Microarrays
Matthias D. Hofer, Tara J. Browne, Le He, Rolf I. Skotheim, Ragnhild A. Lothe, and Mark A. Rubin
Clin Cancer Res 2005 11: 5722-5729. [Abstract] [Full Text] [PDF]  

Gene Signatures of Progression and Metastasis in Renal Cell Cancer
Jon Jones, Hasan Otu, Dimitrios Spentzos, Shakirahmed Kolia, Mehmet Inan, Wolf D. Beecken, Christian Fellbaum, Xuesong Gu, Marie Joseph, Allan J. Pantuck, Dietger Jonas, and Towia A. Libermann
Clin Cancer Res 2005 11: 5730-5739. [Abstract] [Full Text] [PDF]  

Comprehensive Analysis of CDKN2A Status in Microdissected Urothelial Cell Carcinoma Reveals Potential Haploinsufficiency, a High Frequency of Homozygous Co-deletion and Associations with Clinical Phenotype
Emma J. Chapman, Patricia Harnden, Philip Chambers, Colin Johnston, and Margaret A. Knowles
Clin Cancer Res 2005 11: 5740-5747. [Abstract] [Full Text] [PDF]  

Decreased T-Cell Receptor Excision Circles in Cutaneous T-Cell Lymphoma
Kei-ichi Yamanaka, Nikhil Yawalkar, David A. Jones, Daniel Hurwitz, Katalin Ferenczi, Sara Eapen, and Thomas S. Kupper
Clin Cancer Res 2005 11: 5748-5755. [Abstract] [Full Text] [PDF]  

The Fragile Histidine Triad Gene: A Molecular Link Between Cigarette Smoking and Cervical Cancer
Christine H. Holschneider, Rae Lynn Baldwin, Kiran Tumber, Chisa Aoyama, and Beth Y. Karlan
Clin Cancer Res 2005 11: 5756-5763. [Abstract] [Full Text] [PDF]  

The IgLON Family in Epithelial Ovarian Cancer: Expression Profiles and Clinicopathologic Correlates
Evangelos Ntougkos, Robert Rush, Diane Scott, Tobias Frankenberg, Hani Gabra, John F. Smyth, and Grant C. Sellar
Clin Cancer Res 2005 11: 5764-5768. [Abstract] [Full Text] [PDF]  

WOX1 Is Essential for UVB Irradiation–Induced Apoptosis and Down-Regulated via Translational Blockade in UVB-Induced Cutaneous Squamous Cell Carcinoma In vivo
Feng-Jie Lai, Ching-Li Cheng, Shur-Tzu Chen, Chin-Han Wu, Li-Jin Hsu, J. Yu-Yun Lee, Sheau-Chiou Chao, Maw-Chang Sheen, Ching-Liang Shen, Nan-Shan Chang, and Hamm-Ming Sheu
Clin Cancer Res 2005 11: 5769-5777. [Abstract] [Full Text] [PDF]  

Expression of Autocrine Motility Factor Correlates with the Angiogenic Phenotype of and Poor Prognosis for Human Gastric Cancer
Weida Gong, Yixing Jiang, Liwei Wang, Daoyan Wei, James Yao, Suyun Huang, Shengyun Fang, and Keping Xie
Clin Cancer Res 2005 11: 5778-5783. [Abstract] [Full Text] [PDF]  

Phosphorylation of the 6-Phosphofructo-2-Kinase/Fructose 2,6-Bisphosphatase/PFKFB3 Family of Glycolytic Regulators in Human Cancer
Hidenori Bando, Toshiya Atsumi, Taro Nishio, Hirokatsu Niwa, Shinya Mishima, Chikara Shimizu, Narihito Yoshioka, Richard Bucala, and Takao Koike
Clin Cancer Res 2005 11: 5784-5792. [Abstract] [Full Text] [PDF]  

Cytochrome P450 1B1 Is Overexpressed and Regulated by Hypomethylation in Prostate Cancer
Takashi Tokizane, Hiroaki Shiina, Mikio Igawa, Hideki Enokida, Shinji Urakami, Toshifumi Kawakami, Tatsuya Ogishima, Steven T. Okino, Long-Cheng Li, Yuichiro Tanaka, Norio Nonomura, Akihiko Okuyama, and Rajvir Dahiya
Clin Cancer Res 2005 11: 5793-5801. [Abstract] [Full Text] [PDF]  

Role of Mononuclear Cells and Inflammatory Cytokines in Pancreatic Cancer-Related Cachexia
Marc E. Martignoni, Phillipp Kunze, Wulf Hildebrandt, Beat Künzli, Pascal Berberat, Thomas Giese, Oliver Klöters, Jürgen Hammer, Markus W. Büchler, Nathalia A. Giese, and Helmut Friess
Clin Cancer Res 2005 11: 5802-5808. [Abstract] [Full Text] [PDF]  

Cyr61 Induces Gastric Cancer Cell Motility/Invasion via Activation of the Integrin/Nuclear Factor-{kappa}B/Cyclooxygenase-2 Signaling Pathway
Ming-Tsai Lin, Chung-Yaou Zuon, Cheng-Chi Chang, Szu-Ta Chen, Chih-Ping Chen, Been-Ren Lin, Ming-Yang Wang, Yung-Ming Jeng, King-Jen Chang, Po-Huang Lee, Wei-Jao Chen, and Min-Liang Kuo
Clin Cancer Res 2005 11: 5809-5820. [Abstract] [Full Text] [PDF]  

Alteration of Gene Expression in Human Hepatocellular Carcinoma with Integrated Hepatitis B Virus DNA
Akihiro Tamori, Yoshihiro Yamanishi, Shuichi Kawashima, Minoru Kanehisa, Masaru Enomoto, Hiromu Tanaka, Shoji Kubo, Susumu Shiomi, and Shuhei Nishiguchi
Clin Cancer Res 2005 11: 5821-5826. [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Early Antiangiogenic Activity of SU11248 Evaluated In vivo by Dynamic Contrast-Enhanced Magnetic Resonance Imaging in an Experimental Model of Colon Carcinoma
Pasquina Marzola, Anna Degrassi, Laura Calderan, Paolo Farace, Elena Nicolato, Caterina Crescimanno, Marco Sandri, Anna Giusti, Enrico Pesenti, Andrea Terron, Andrea Sbarbati, and Francesco Osculati
Clin Cancer Res 2005 11: 5827-5832. [Abstract] [Full Text] [PDF]  

Characterization of a New Antibody Raised against the NH2 Terminus of P-Glycoprotein
Prema S. Rao, Rajgopal Govindarajan, Kavita B. Mallya, William West, and U. Subrahmanyeswara Rao
Clin Cancer Res 2005 11: 5833-5839. [Abstract] [Full Text] [PDF]  

New Monoclonal Antibodies to Mesothelin Useful for Immunohistochemistry, Fluorescence-Activated Cell Sorting, Western Blotting, and ELISA
Masanori Onda, Mark Willingham, Satoshi Nagata, Tapan K. Bera, Richard Beers, Mitchell Ho, Raffit Hassan, Robert J. Kreitman, and Ira Pastan
Clin Cancer Res 2005 11: 5840-5846. [Abstract] [Full Text] [PDF]  

Proteomic Analysis of Apoptotic Pathways Reveals Prognostic Factors in Follicular Lymphoma
Christian Gulmann, Virginia Espina, Emanuel Petricoin, III, Dan L. Longo, Mariarita Santi, Turid Knutsen, Mark Raffeld, Elaine S. Jaffe, Lance A. Liotta, and Andrew L. Feldman
Clin Cancer Res 2005 11: 5847-5855. [Abstract] [Full Text] [PDF]  

Quantitative Determination of Nuclear and Cytoplasmic Epidermal Growth Factor Receptor Expression in Oropharyngeal Squamous Cell Cancer by Using Automated Quantitative Analysis
Amanda Psyrri, Ziwei Yu, Paul M. Weinberger, Clarence Sasaki, Bruce Haffty, Robert Camp, David Rimm, and Barbara Ann Burtness
Clin Cancer Res 2005 11: 5856-5862. [Abstract] [Full Text] [PDF]  

Activation of Signal Transducer and Activator of Transcription-5 in Prostate Cancer Predicts Early Recurrence
Hongzhen Li, Ying Zhang, Andrew Glass, Tobias Zellweger, Edmund Gehan, Lukas Bubendorf, Edward P. Gelmann, and Marja T. Nevalainen
Clin Cancer Res 2005 11: 5863-5868. [Abstract] [Full Text] [PDF]  

P-Cadherin Overexpression Is an Indicator of Clinical Outcome in Invasive Breast Carcinomas and Is Associated with CDH3 Promoter Hypomethylation
Joana Paredes, André Albergaria, João T. Oliveira, Carmen Jerónimo, Fernanda Milanezi, and Fernando C. Schmitt
Clin Cancer Res 2005 11: 5869-5877. [Abstract] [Full Text] [PDF]  

Activating Mutations in the Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor Are Associated with Improved Survival in Gefitinib-Treated Chemorefractory Lung Adenocarcinomas
Miguel Taron, Yukito Ichinose, Rafael Rosell, Tony Mok, Bartomeu Massuti, Lurdes Zamora, Jose Luis Mate, Christian Manegold, Mayumi Ono, Cristina Queralt, Thierry Jahan, Jose Javier Sanchez, Maria Sanchez-Ronco, Victor Hsue, David Jablons, Jose Miguel Sanchez, and Teresa Moran
Clin Cancer Res 2005 11: 5878-5885. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Analysis of the DPYD Gene Implicated in 5-Fluorouracil Catabolism in a Cohort of Caucasian Individuals
Katharina Seck, Silvia Riemer, Ronald Kates, Tobias Ullrich, Verena Lutz, Nadia Harbeck, Manfred Schmitt, Marion Kiechle, Robert Diasio, and Eva Gross
Clin Cancer Res 2005 11: 5886-5892. [Abstract] [Full Text] [PDF]  

Pharmacokinetics of Dactinomycin in a Pediatric Patient Population: a United Kingdom Children's Cancer Study Group Study
Gareth J. Veal, Michael Cole, Julie Errington, Annie Parry, Juliet Hale, Andrew D.J. Pearson, Karen Howe, Julia C. Chisholm, Carol Beane, Bernadette Brennan, Fiona Waters, Adam Glaser, Sue Hemsworth, Heather McDowell, Yvonne Wright, Kathy Pritchard-Jones, Ross Pinkerton, Gail Jenner, James Nicholson, Ann M. Elsworth, Alan V. Boddy, and UKCCSG Pharmacology Working Group
Clin Cancer Res 2005 11: 5893-5899. [Abstract] [Full Text] [PDF]  

Immunologic Evaluation of Personalized Peptide Vaccination for Patients with Advanced Malignant Glioma
Naoki Yajima, Ryuya Yamanaka, Takashi Mine, Naoto Tsuchiya, Jumpei Homma, Masakazu Sano, Terukazu Kuramoto, Yayoi Obata, Nobukazu Komatsu, Yoshimi Arima, Akira Yamada, Minoru Shigemori, Kyogo Itoh, and Ryuichi Tanaka
Clin Cancer Res 2005 11: 5900-5911. [Abstract] [Full Text] [PDF]  

Phase I Study of Combined Pegylated Liposomal Doxorubicin with Protracted Daily Topotecan for Ovarian Cancer
Deepu Mirchandani, Howard Hochster, Anne Hamilton, Leonard Liebes, Herman Yee, John P. Curtin, Sang Lee, Joan Sorich, Cornelia Dellenbaugh, and Franco M. Muggia
Clin Cancer Res 2005 11: 5912-5919. [Abstract] [Full Text] [PDF]  

High-Dose Radioimmunotherapy Combined with Fixed, Low-Dose Paclitaxel in Metastatic Prostate and Breast Cancer by Using a MUC-1 Monoclonal Antibody, m170, Linked to Indium-111/Yttrium-90 via a Cathepsin Cleavable Linker with Cyclosporine to Prevent Human Anti-mouse Antibody
Carol M. Richman, Sally J. DeNardo, Robert T. O'Donnell, Aina Yuan, Sui Shen, Desiree S. Goldstein, Joseph M. Tuscano, Ted Wun, Helen K. Chew, Primo N. Lara, David L. Kukis, Arutselvan Natarajan, Claude F. Meares, Kathleen R. Lamborn, and Gerald L. DeNardo
Clin Cancer Res 2005 11: 5920-5927. [Abstract] [Full Text] [PDF]  

Objective Responses in Patients with Malignant Melanoma or Renal Cell Cancer in Early Clinical Studies Do Not Predict Regulatory Approval
John Goffin, Stefan Baral, Dongsheng Tu, Dora Nomikos, and Lesley Seymour
Clin Cancer Res 2005 11: 5928-5934. [Abstract] [Full Text] [PDF]  

Phase 1 Trial of Flavopiridol Combined with Cisplatin or Carboplatin in Patients with Advanced Malignancies with the Assessment of Pharmacokinetic and Pharmacodynamic End Points
Keith C. Bible, Janet L. Lensing, Sacha A. Nelson, Yean K. Lee, Joel M. Reid, Matthew M. Ames, Crescent R. Isham, Jill Piens, Stacie L. Rubin, Joseph Rubin, Scott H. Kaufmann, Pamela J. Atherton, Jeffrey A. Sloan, Michelle K. Daiss, Alex A. Adjei, and Charles Erlichman
Clin Cancer Res 2005 11: 5935-5941. [Abstract] [Full Text] [PDF]  

Phase I and Pharmacokinetic Study of Weekly Docetaxel, Cisplatin, and Daily Capecitabine in Patients with Advanced Solid Tumors
Marwan G. Fakih, Patrick J. Creaven, Nithya Ramnath, Donald Trump, Milind Javle, Sandra Strychor, Trisha V.W. Repinski, Beth A. Zamboni, James K. Schwarz, Renee A. French, and William C. Zamboni
Clin Cancer Res 2005 11: 5942-5949. [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

CpG Immunomer DNA Enhances Antisense Protein Kinase A RI{alpha} Inhibition of Multidrug-Resistant Colon Carcinoma Growth in Nude Mice: Molecular Basis for Combinatorial Therapy
Maria V. Nesterova, Natalie R. Johnson, Trina Stewart, Scott Abrams, and Yoon S. Cho-Chung
Clin Cancer Res 2005 11: 5950-5955. [Abstract] [Full Text] [PDF]  

Radiation and Transforming Growth Factor-ß Cooperate in Transcriptional Activation of the Profibrotic Plasminogen Activator Inhibitor-1 Gene
Jurre Hageman, Bart J. Eggen, Tom Rozema, Kevin Damman, Harm H. Kampinga, and Robert P. Coppes
Clin Cancer Res 2005 11: 5956-5964. [Abstract] [Full Text] [PDF]  

PEX-Producing Human Neural Stem Cells Inhibit Tumor Growth in a Mouse Glioma Model
Seung-Ki Kim, Theresa G. Cargioli, Marcelle Machluf, Wendy Yang, Yanping Sun, Ruqayyah Al-Hashem, Seung U. Kim, Peter M. Black, and Rona S. Carroll
Clin Cancer Res 2005 11: 5965-5970. [Abstract] [Full Text] [PDF]  

Generation of Rituximab Polymer May Cause Hyper-Cross-linking–Induced Apoptosis in Non-Hodgkin's Lymphomas
Nan Zhang, Leslie A. Khawli, Peisheng Hu, and Alan L. Epstein
Clin Cancer Res 2005 11: 5971-5980. [Abstract] [Full Text] [PDF]  

Plasma and Cerebrospinal Fluid Pharmacokinetics of Clofarabine in Nonhuman Primates
Stacey L. Berg, Peter L. Bonate, Jed G. Nuchtern, Robert Dauser, Leticia McGuffey, Bruce Bernacky, and Susan M. Blaney
Clin Cancer Res 2005 11: 5981-5983. [Abstract] [Full Text] [PDF]  

Immunomodulatory Drug CC-5013 or CC-4047 and Rituximab Enhance Antitumor Activity in a Severe Combined Immunodeficient Mouse Lymphoma Model
Francisco J. Hernandez-Ilizaliturri, Nishitha Reddy, Beata Holkova, Edris Ottman, and Myron S. Czuczman
Clin Cancer Res 2005 11: 5984-5992. [Abstract] [Full Text] [PDF]  

Phase I/II Combined Chemoimmunotherapy with Carcinoembryonic Antigen–Derived HLA-A2–Restricted CAP-1 Peptide and Irinotecan, 5-Fluorouracil, and Leucovorin in Patients with Primary Metastatic Colorectal Cancer
Martin R. Weihrauch, Sascha Ansén, Elke Jurkiewicz, Caroline Geisen, Zhinan Xia, Karen S. Anderson, Edith Gracien, Manuel Schmidt, Burghardt Wittig, Volker Diehl, Juergen Wolf, Heribert Bohlen, and Lee M. Nadler
Clin Cancer Res 2005 11: 5993-6001. [Abstract] [Full Text] [PDF]  

Pseudolaric Acid B, a Novel Microtubule-Destabilizing Agent That Circumvents Multidrug Resistance Phenotype and Exhibits Antitumor Activity In vivo
Vincent K.W. Wong, Pauline Chiu, Stephen S.M. Chung, Larry M.C. Chow, Yun-Zhe Zhao, Burton B. Yang, and Ben C.B. Ko
Clin Cancer Res 2005 11: 6002-6011. [Abstract] [Full Text] [PDF]  

Targeting Matrilysin and Its Impact on Tumor Growth In vivo: The Potential Implications in Breast Cancer Therapy
Wen G. Jiang, Gaynor Davies, Tracey A. Martin, Christian Parr, Gareth Watkins, Malcolm D. Mason, Kefah Mokbel, and Robert E. Mansel
Clin Cancer Res 2005 11: 6012-6019. [Abstract] [Full Text] [PDF]  

Adeno-Associated Virus Vector-Mediated Systemic Delivery of IFN-ß Combined with Low-Dose Cyclophosphamide Affects Tumor Regression in Murine Neuroblastoma Models
Christian J. Streck, Paxton V. Dickson, Catherine Y.C. Ng, Junfang Zhou, John T. Gray, Amit C. Nathwani, and Andrew M. Davidoff
Clin Cancer Res 2005 11: 6020-6029. [Abstract] [Full Text] [PDF]  

Indoleamine 2,3-Dioxygenase Serves as a Marker of Poor Prognosis in Gene Expression Profiles of Serous Ovarian Cancer Cells
Aikou Okamoto, Takashi Nikaido, Kazunori Ochiai, Satoshi Takakura, Misato Saito, Yuko Aoki, Nobuya Ishii, Nozomu Yanaihara, Kyosuke Yamada, Osamu Takikawa, Rie Kawaguchi, Seiji Isonishi, Tadao Tanaka, and Mitsuyoshi Urashima
Clin Cancer Res 2005 11: 6030-6039. [Abstract] [Full Text] [PDF]  

Green Tea Component, Catechin, Induces Apoptosis of Human Malignant B Cells via Production of Reactive Oxygen Species
Tomonori Nakazato, Keisuke Ito, Yasuo Ikeda, and Masahiro Kizaki
Clin Cancer Res 2005 11: 6040-6049. [Abstract] [Full Text] [PDF]  

Genetic Variations in the Glucocorticoid Receptor Gene Are Not Related to Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia
Wim J.E. Tissing, Jules P.P. Meijerink, Monique L. den Boer, Bas Brinkhof, Elisabeth F.C. van Rossum, Elisabeth R. van Wering, Jan W. Koper, Pieter Sonneveld, and Rob Pieters
Clin Cancer Res 2005 11: 6050-6056. [Abstract] [Full Text] [PDF]  

Characterization of a R115777-Resistant Human Multiple Myeloma Cell Line with Cross-Resistance to PS-341
Robert Buzzeo, Steven Enkemann, Rama Nimmanapalli, Melissa Alsina, Mathias G. Lichtenheld, William S. Dalton, and Darrin M. Beaupre
Clin Cancer Res 2005 11: 6057-6064. [Abstract] [Full Text] [PDF]  

Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer
Ho-Young Lee, Seung-Hyun Oh, Young-Ah Suh, Jin Hyen Baek, Vali Papadimitrakopoulou, Suyun Huang, and Waun Ki Hong
Clin Cancer Res 2005 11: 6065-6074. [Abstract] [Full Text] [PDF]  

Overexpression of Cyclin D1 Promotes Tumor Cell Growth and Confers Resistance to Cisplatin-Mediated Apoptosis in an Elastase-myc Transgene–Expressing Pancreatic Tumor Cell Line
Hector Biliran, Jr., Yong Wang, Sanjeev Banerjee, Haiming Xu, Henry Heng, Archana Thakur, Aliccia Bollig, Fazlul H. Sarkar, and Joshua D. Liao
Clin Cancer Res 2005 11: 6075-6086. [Abstract] [Full Text] [PDF]  

Cancer Prevention:

Levels of Prostaglandin E Metabolite, the Major Urinary Metabolite of Prostaglandin E2, Are Increased in Smokers
Neil D. Gross, Jay O. Boyle, Jason D. Morrow, Myles K. Williams, Chaya S. Moskowitz, Kotha Subbaramaiah, Andrew J. Dannenberg, and Anna J. Duffield-Lillico
Clin Cancer Res 2005 11: 6087-6093. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

The Potential and Suitability of 2-Methoxyestradiol in Cancer Therapy
Carolyn Sidor, Robert D'Amato, Kathy D. Miller, Alastair Stewart, Tara E. Sutherland, Michael Schuliga, Trudi Harris, Lilly Quan, David McAllister, Brett Pool, Bedrich Eckhardt, and Robin Anderson
Clin Cancer Res 2005 11: 6094-6096. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation
Copyright © 2005 by the American Association for Cancer Research.