Featured Articles:

   Clinical Trials:

Monika E. Hegi, Annie-Claire Diserens, Sophie Godard, Pierre-Yves Dietrich, Luca Regli, Sandrine Ostermann, Philippe Otten, Guy Van Melle, Nicolas de Tribolet, and Roger Stupp

Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide
Clin Cancer Res 2004 10: 1871-1874. [Abstract] [Full Text] [PDF]  

David Alberts, James Ranger-Moore, Janine Einspahr, Kathylynn Saboda, Paul Bozzo, Yun Liu, Xiao-chun Xu, Reuben Lotan, James Warneke, Stuart Salasche, Suzanne Stratton, Norman Levine, Rayna Goldman, Marcy Islas, Laura Duckett, Deborah Thompson, and Peter Bartels

Safety and Efficacy of Dose-Intensive Oral Vitamin A in Subjects with Sun-Damaged Skin
Clin Cancer Res 2004 10: 1875-1880. [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Marco Burroni, Rosamaria Corona, Giordana Dell’Eva, Francesco Sera, Riccardo Bono, Pietro Puddu, Roberto Perotti, Franco Nobile, Lucio Andreassi, and Pietro Rubegni

Melanoma Computer-Aided Diagnosis: Reliability and Feasibility Study
Clin Cancer Res 2004 10: 1881-1886. [Abstract] [Full Text] [PDF]  

Essel Dulaimi, Robert G. Uzzo, Richard E. Greenberg, Tahseen Al-Saleem, and Paul Cairns

Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel
Clin Cancer Res 2004 10: 1887-1893. [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Yong J. Lee, Christopher J. Froelich, Naoya Fujita, Takashi Tsuruo, and Jin H. Kim

Reconstitution of Caspase-3 Confers Low Glucose-Enhanced Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Cytotoxicity and Akt Cleavage
Clin Cancer Res 2004 10: 1894-1900. [Abstract] [Full Text] [PDF]  

Karin Jöhrer, Katrin Janke, Jens Krugmann, Michael Fiegl, and Richard Greil

Transendothelial Migration of Myeloma Cells Is Increased by Tumor Necrosis Factor (TNF)- via TNF Receptor 2 and Autocrine Up-Regulation of MCP-1
Clin Cancer Res 2004 10: 1901-1910. [Abstract] [Full Text] [PDF]  

Shouwei Han, Neil Sidell, Paul B. Fisher, and Jesse Roman

Up-regulation of p21 Gene Expression by Peroxisome Proliferator-Activated Receptor in Human Lung Carcinoma Cells
Clin Cancer Res 2004 10: 1911-1919. [Abstract] [Full Text] [PDF]  

Li-Zhen He, Venky Ramakrishna, John E. Connolly, Xi-Tao Wang, Patricia A. Smith, Charles L. Jones, Maria Valkova-Valchanova, Alahari Arunakumari, John F. Treml, Joel Goldstein, Paul K. Wallace, Tibor Keler, and Michael J. Endres

A Novel Human Cancer Vaccine Elicits Cellular Responses to the Tumor-Associated Antigen, Human Chorionic Gonadotropin ß
Clin Cancer Res 2004 10: 1920-1927. [Abstract] [Full Text] [PDF]  

Regular Articles:

   Clinical Trials:

Marco B. Polee, Alex Sparreboom, Ferry A. L. M. Eskens, Ronald Hoekstra, Jacqueline van de Schaaf, Jaap Verweij, Gerrit Stoter, and Ate van der Gaast

A Phase I and Pharmacokinetic Study of Weekly Paclitaxel and Carboplatin in Patients with Metastatic Esophageal Cancer
Clin Cancer Res 2004 10: 1928-1934. [Abstract] [Full Text] [PDF]  

David Pelloso, Katherine Cyran, Lynette Timmons, Brian T. Williams, and Michael J. Robertson

Immunological Consequences of Interleukin 12 Administration after Autologous Stem Cell Transplantation
Clin Cancer Res 2004 10: 1935-1942. [Abstract] [Full Text] [PDF]  

Edgardo Rivera, Vicente Valero, Deborah Francis, Aviva G. Asnis, Larry J. Schaaf, Barbara Duncan, and Gabriel N. Hortobagyi

Pilot Study Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of the Combination of Exemestane and Tamoxifen
Clin Cancer Res 2004 10: 1943-1948. [Abstract] [Full Text] [PDF]  

Lia van Zuylen, John Bridgewater, Alex Sparreboom, Ferry A. L. M. Eskens, Peter de Bruijn, Ivo Sklenar, Andre S. T. Planting, Les Choi, Douglas Bootle, Christian Mueller, Jonathan A. Ledermann, and Jaap Verweij

Phase I and Pharmacokinetic Study of the Polyamine Synthesis Inhibitor SAM486A in Combination with 5-Fluorouracil/ Leucovorin in Metastatic Colorectal Cancer
Clin Cancer Res 2004 10: 1949-1955. [Abstract] [Full Text] [PDF]  

Athanassios Argiris, Bruce E. Brockstein, Daniel J. Haraf, Kerstin M. Stenson, Bharat B. Mittal, Merrill S. Kies, Fred R. Rosen, Borko Jovanovic, and Everett E. Vokes

Competing Causes of Death and Second Primary Tumors in Patients with Locoregionally Advanced Head and Neck Cancer Treated with Chemoradiotherapy
Clin Cancer Res 2004 10: 1956-1962. [Abstract] [Full Text] [PDF]  

Naiyer A. Rizvi, Jeffrey S. Humphrey, Elizabeth A. Ness, Michael D. Johnson, Elora Gupta, Kathleen Williams, Diana J. Daly, Daryl Sonnichsen, Delina Conway, John Marshall, and Herbert Hurwitz

A Phase I Study of Oral BMS-275291, a Novel Nonhydroxamate Sheddase-Sparing Matrix Metalloproteinase Inhibitor, in Patients with Advanced or Metastatic Cancer
Clin Cancer Res 2004 10: 1963-1970. [Abstract] [Full Text] [PDF]  

Kathy D. Miller, Thomas J. Saphner, David M. Waterhouse, T.-T. Chen, Anita Rush-Taylor, Joseph A. Sparano, Antonio C. Wolff, Melody A. Cobleigh, Susan Galbraith, and George W. Sledge

A Randomized Phase II Feasibility Trial of BMS-275291 in Patients with Early Stage Breast Cancer
Clin Cancer Res 2004 10: 1971-1975. [Abstract] [Full Text] [PDF]  

Sharyn D. Baker, Ming Zhao, Carlton K. K. Lee, Jaap Verweij, Yelena Zabelina, Julie R. Brahmer, Antonio C. Wolff, Alex Sparreboom, and Michael A. Carducci

Comparative Pharmacokinetics of Weekly and Every-Three-Weeks Docetaxel
Clin Cancer Res 2004 10: 1976-1983. [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Chang Qi Zhu, Fiona H. Blackhall, Melania Pintilie, Pratibha Iyengar, Ni Liu, James Ho, Taylor Chomiak, Davina Lau, Timothy Winton, Frances A. Shepherd, and Ming-Sound Tsao

Skp2 Gene Copy Number Aberrations Are Common in Non-Small Cell Lung Carcinoma, and Its Overexpression in Tumors with ras Mutation Is a Poor Prognostic Marker
Clin Cancer Res 2004 10: 1984-1991. [Abstract] [Full Text] [PDF]  

Shahrokh F. Shariat, Michael W. Kattan, Erica Traxel, Ben Andrews, Kuichun Zhu, Thomas M. Wheeler, and Kevin M. Slawin

Association of Pre- and Postoperative Plasma Levels of Transforming Growth Factor ß₁ and Interleukin 6 and Its Soluble Receptor with Prostate Cancer Progression
Clin Cancer Res 2004 10: 1992-1999. [Abstract] [Full Text] [PDF]  

Katsuhiko Terasawa, Satoru Sagae, Minoru Toyota, Kuniko Tsukada, Kazuhiro Ogi, Ayumi Satoh, Hiroaki Mita, Kohzoh Imai, Takashi Tokino, and Ryuichi Kudo

Epigenetic Inactivation of TMS1/ASC in Ovarian Cancer
Clin Cancer Res 2004 10: 2000-2006. [Abstract] [Full Text] [PDF]  

Takeshi Tomonaga, Kazuyuki Matsushita, Seiko Yamaguchi, Masamichi Oh-Ishi, Yoshio Kodera, Tadakazu Maeda, Hideaki Shimada, Takenori Ochiai, and Fumio Nomura

Identification of Altered Protein Expression and Post-Translational Modifications in Primary Colorectal Cancer by Using Agarose Two-Dimensional Gel Electrophoresis
Clin Cancer Res 2004 10: 2007-2014. [Abstract] [Full Text] [PDF]  

Masahiro Sasaki, Yuichiro Tanaka, Steven T. Okino, Mitsuharu Nomoto, Suguru Yonezawa, Masayuki Nakagawa, Seiichiro Fujimoto, Noriaki Sakuragi, and Rajvir Dahiya

Polymorphisms of the CYP1B1 Gene as Risk Factors for Human Renal Cell Cancer
Clin Cancer Res 2004 10: 2015-2019. [Abstract] [Full Text] [PDF]  

Katerina Dvorakova, Claire M. Payne, Lois Ramsey, Hana Holubec, Richard Sampliner, Jessica Dominguez, Bohuslav Dvorak, Harris Bernstein, Carol Bernstein, Anil Prasad, Ronnie Fass, Haiyan Cui, and Harinder Garewal

Increased Expression and Secretion of Interleukin-6 in Patients with Barrett’s Esophagus
Clin Cancer Res 2004 10: 2020-2028. [Abstract] [Full Text] [PDF]  

William D. Foulkes, Kelly Metcalfe, Ping Sun, Wedad M. Hanna, Henry T. Lynch, Parviz Ghadirian, Nadine Tung, Olufunmilayo I. Olopade, Barbara L. Weber, Jane McLennan, Ivo A. Olivotto, Louis R. Bégin, and Steven A. Narod

Estrogen Receptor Status in BRCA1- and BRCA2-Related Breast Cancer: The Influence of Age, Grade, and Histological Type
Clin Cancer Res 2004 10: 2029-2034. [Abstract] [Full Text] [PDF]  

Yukiko Yano, Naoya Uematsu, Tohru Yashiro, Hisato Hara, Ei Ueno, Masanao Miwa, Gozoh Tsujimoto, Yuji Aiyoshi, and Kazuhiko Uchida

Gene Expression Profiling Identifies Platelet-Derived Growth Factor as a Diagnostic Molecular Marker for Papillary Thyroid Carcinoma
Clin Cancer Res 2004 10: 2035-2043. [Abstract] [Full Text] [PDF]  

Jean-Philippe Coppe, Yoko Itahana, Dan H. Moore, James L. Bennington, and Pierre-Yves Desprez

Id-1 and Id-2 Proteins as Molecular Markers for Human Prostate Cancer Progression
Clin Cancer Res 2004 10: 2044-2051. [Abstract] [Full Text] [PDF]  

Jyoti Mehrotra, M. Michelle Ganpat, Yasmine Kanaan, Mary Jo Fackler, Megan McVeigh, Jaana Lahti-Domenici, Kornelia Polyak, Pedram Argani, Tammy Naab, Elizabeth Garrett, Giovanni Parmigiani, Carolyn Broome, and Saraswati Sukumar

Estrogen Receptor/Progesterone Receptor-Negative Breast Cancers of Young African-American Women Have a Higher Frequency of Methylation of Multiple Genes than Those of Caucasian Women¹
Clin Cancer Res 2004 10: 2052-2057. [Abstract] [Full Text] [PDF]  

Sylvaine Galiègue, Pierre Casellas, Andrew Kramar, Norbert Tinel, and Joelle Simony-Lafontaine

Immunohistochemical Assessment of the Peripheral Benzodiazepine Receptor in Breast Cancer and Its Relationship with Survival
Clin Cancer Res 2004 10: 2058-2064. [Abstract] [Full Text] [PDF]  

Yung-Ming Jeng, Shian-Yang Peng, Chiao-Ying Lin, and Hey-Chi Hsu

Overexpression and Amplification of Aurora-A in Hepatocellular Carcinoma
Clin Cancer Res 2004 10: 2065-2071. [Abstract] [Full Text] [PDF]  

Dong Xie, Dong Yin, He-Jing Wang, Gen-Tao Liu, Robert Elashoff, Keith Black, and H. Phillip Koeffler

Levels of Expression of CYR61 and CTGF Are Prognostic for Tumor Progression and Survival of Individuals with Gliomas
Clin Cancer Res 2004 10: 2072-2081. [Abstract] [Full Text] [PDF]  

Hideaki Dote, Shinichi Toyooka, Kazunori Tsukuda, Masaaki Yano, Mamoru Ouchida, Hiroyoshi Doihara, Makoto Suzuki, Hong Chen, Jer-Tsong Hsieh, Adi F. Gazdar, and Nobuyoshi Shimizu

Aberrant Promoter Methylation in Human DAB2 Interactive Protein (hDAB2IP) Gene in Breast Cancer
Clin Cancer Res 2004 10: 2082-2089. [Abstract] [Full Text] [PDF]  

Naoki Miyahara, Junichi Shoda, Toru Kawamoto, Masato Furukawa, Tetsuya Ueda, Takeshi Todoroki, Naomi Tanaka, Kenichi Matsuo, Yuji Yamada, Kimitoshi Kohno, and Tatsuro Irimura

Expression of UDP-N-Acetyl--D-Galactosamine-Polypeptide N-Acetylgalactosaminyltransferase Isozyme 3 in the Subserosal Layer Correlates with Postsurgical Survival of Pathological Tumor Stage 2 Carcinoma of the Gallbladder
Clin Cancer Res 2004 10: 2090-2099. [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Peter Mullen, Fiona McPhillips, Kenneth MacLeod, Brett Monia, John F. Smyth, and Simon P. Langdon

Antisense Oligonucleotide Targeting of Raf-1: Importance of Raf-1 mRNA Expression Levels and Raf-1-Dependent Signaling in Determining Growth Response in Ovarian Cancer
Clin Cancer Res 2004 10: 2100-2108. [Abstract] [Full Text] [PDF]  

Christiane J. Bruns, Gudrun E. Koehl, Markus Guba, Maksim Yezhelyev, Markus Steinbauer, Hendrik Seeliger, Astrid Schwend, Anna Hoehn, Karl-Walter Jauch, and Edward K. Geissler

Rapamycin-Induced Endothelial Cell Death and Tumor Vessel Thrombosis Potentiate Cytotoxic Therapy against Pancreatic Cancer
Clin Cancer Res 2004 10: 2109-2119. [Abstract] [Full Text] [PDF]  

Keisuke Ito, Tomonori Nakazato, Akira Murakami, Kenji Yamato, Yoshitaka Miyakawa, Taketo Yamada, Nobumichi Hozumi, Hajime Ohigashi, Yasuo Ikeda, and Masahiro Kizaki

Induction of Apoptosis in Human Myeloid Leukemic Cells by 1'-Acetoxychavicol Acetate through a Mitochondrial- and Fas-Mediated Dual Mechanism
Clin Cancer Res 2004 10: 2120-2130. [Abstract] [Full Text] [PDF]  

Zhijian Yang, Junhua Wang, Takayuki Yoshioka, Baoqiu Li, Quan Lu, Shukuan Li, Xinghua Sun, Yuying Tan, Shigeo Yagi, Eugene P. Frenkel, and Robert M. Hoffman

Pharmacokinetics, Methionine Depletion, and Antigenicity of Recombinant Methioninase in Primates
Clin Cancer Res 2004 10: 2131-2138. [Abstract] [Full Text] [PDF]  

Kwong-Yok Tsang, Claudia Palena, James Gulley, Philip Arlen, and Jeffrey Schlom

A Human Cytotoxic T-Lymphocyte Epitope and Its Agonist Epitope from the Nonvariable Number of Tandem Repeat Sequence of MUC-1
Clin Cancer Res 2004 10: 2139-2149. [Abstract] [Full Text] [PDF]  

Carolina Armengol, Gemma Tarafa, Loreto Boix, Manel Solé, Rosa Queralt, Dolors Costa, Oriol Bachs, Jordi Bruix, and Gabriel Capellá

Orthotopic Implantation of Human Hepatocellular Carcinoma in Mice: Analysis of Tumor Progression and Establishment of the BCLC-9 Cell Line
Clin Cancer Res 2004 10: 2150-2157. [Abstract] [Full Text] [PDF]  

John Boyer, Estelle G. McLean, Somaiah Aroori, Peter Wilson, Andrea McCulla, P. Declan Carey, Daniel B. Longley, and Patrick G. Johnston

Characterization of p53 Wild-Type and Null Isogenic Colorectal Cancer Cell Lines Resistant to 5-Fluorouracil, Oxaliplatin, and Irinotecan
Clin Cancer Res 2004 10: 2158-2167. [Abstract] [Full Text] [PDF]  

Lars H. Lindner, Martin E. Eichhorn, Hansjoerg Eibl, Nicole Teichert, Marcus Schmitt-Sody, Rolf D. Issels, and Marc Dellian

Novel Temperature-Sensitive Liposomes with Prolonged Circulation Time
Clin Cancer Res 2004 10: 2168-2178. [Abstract] [Full Text] [PDF]  

Jennifer Walter-Yohrling, Sharon Morgenbesser, Cecile Rouleau, Rebecca Bagley, Michelle Callahan, William Weber, and Beverly A. Teicher

Murine Endothelial Cell Lines as Models of Tumor Endothelial Cells
Clin Cancer Res 2004 10: 2179-2189. [Abstract] [Full Text] [PDF]  

Sheng-Hong Tseng, Swei-Ming Lin, Jin-Cherng Chen, Yen-Hao Su, Hsin-Yi Huang, Chia-Kang Chen, Po-Yin Lin, and Yun Chen

Resveratrol Suppresses the Angiogenesis and Tumor Growth of Gliomas in Rats
Clin Cancer Res 2004 10: 2190-2202. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.